Results 21 to 30 of about 12,382 (217)

Production of PHB From CO2-Derived Acetate With Minimal Processing Assessed for Space Biomanufacturing

Frontiers in Microbiology, 2021
Providing life-support materials to crewed space exploration missions is pivotal for mission success. However, as missions become more distant and extensive, obtaining these materials from in situ resource utilization is paramount.
Stefano Cestellos-Blanco, Stefano Cestellos-Blanco, Skyler Friedline, Skyler Friedline, Kyle B. Sander, Kyle B. Sander, Anthony J. Abel, Anthony J. Abel, Ji Min Kim, Ji Min Kim, Douglas S. Clark, Douglas S. Clark, Douglas S. Clark, Adam P. Arkin, Adam P. Arkin, Adam P. Arkin, Peidong Yang, Peidong Yang, Peidong Yang, Peidong Yang, Peidong Yang   +20 more
doaj   +1 more source

Introducing Mobile Collaborative Robots into Bioprocessing Environments: Personalised Drug Manufacturing and Environmental Monitoring

Applied Sciences, 2022
Personalised therapeutic drugs are the future of the medical drug sector. For manufacturers, this will require the flexibility to produce many different unique batches within a given facility.
Robins Mathew, Robert McGee, Kevin Roche, Shada Warreth, Nikolaos Papakostas   +4 more
doaj   +1 more source

Mechanistic modeling explains the production dynamics of recombinant adeno-associated virus with the baculovirus expression vector system

Molecular Therapy: Methods & Clinical Development, 2023
Current manufacturing processes for recombinant adeno-associated viruses (rAAVs) have less-than-desired yields and produce significant amounts of empty capsids.
Francesco Destro, John Joseph, Prasanna Srinivasan, Joshua M. Kanter, Caleb Neufeld, Jacqueline M. Wolfrum, Paul W. Barone, Stacy L. Springs, Anthony J. Sinskey, Sylvain Cecchini, Robert M. Kotin, Richard D. Braatz   +11 more
doaj   +1 more source

Diatoms for Carbon Sequestration and Bio-Based Manufacturing

Biology, 2020
Carbon dioxide (CO2) is a major greenhouse gas responsible for climate change. Diatoms, a natural sink of atmospheric CO2, can be cultivated industrially in autotrophic and mixotrophic modes for the purpose of CO2 sequestration.
Deepak Sethi, Thomas O. Butler, Faqih Shuhaili, Seetharaman Vaidyanathan   +3 more
doaj   +1 more source

Biological Considerations in Scaling Up Therapeutic Cell Manufacturing

Frontiers in Pharmacology, 2020
Cell therapeutics — using cells as living drugs — have made advances in many areas of medicine. One of the most clinically studied cell-based therapy products is mesenchymal stromal cells (MSCs), which have shown promising results in promoting tissue ...
Darshana S. Cherian, Tejasvini Bhuvan, Laurence Meagher, Tracy S. P. Heng   +3 more
doaj   +1 more source

Bioproduction of Linalool From Paper Mill Waste

Frontiers in Bioengineering and Biotechnology, 2022
A key challenge in chemicals biomanufacturing is the maintenance of stable, highly productive microbial strains to enable cost-effective fermentation at scale.
Mauro A. Rinaldi, Mauro A. Rinaldi, Shirley Tait, Helen S. Toogood, Helen S. Toogood, Nigel S. Scrutton, Nigel S. Scrutton, Nigel S. Scrutton   +7 more
doaj   +1 more source

Streamlining Natural Products Biomanufacturing With Omics and Machine Learning Driven Microbial Engineering

Frontiers in Bioengineering and Biotechnology, 2020
Increasing demands for the supply of biopharmaceuticals have propelled the advancement of metabolic engineering and synthetic biology strategies for biomanufacturing of bioactive natural products.
Ahmad Bazli Ramzi, Syarul Nataqain Baharum, Hamidun Bunawan, Nigel S. Scrutton   +3 more
doaj   +1 more source

Ionic-liquid-based approaches to improve biopharmaceuticals downstream processing and formulation

Frontiers in Bioengineering and Biotechnology, 2023
The emergence of biopharmaceuticals, including proteins, nucleic acids, peptides, and vaccines, revolutionized the medical field, contributing to significant advances in the prophylaxis and treatment of chronic and life-threatening diseases.
Catarina Almeida, Augusto Q. Pedro, Ana P. M. Tavares, Márcia C. Neves, Mara G. Freire   +4 more
doaj   +1 more source

Improvement In Cranioplasty: Advanced Prosthesis Biomanufacturing [PDF]

, 2017
Additive manufacturing (AM) is a technology that enables the production of models and prosthesis directly from the 3D CAD model facilitating surgical procedures, implant quality and reducing risks. Furthermore, the additive manufacturing has been used to
Jardini, A. L.; Larosa, E.; Kharmandayan, M. A.; Macedo, C. S.; Zavaglia, L. F.; Lambert, R.; Calderoni, D. R.; Ghizoni, M. F.; Bernardes, C. A. C.; Maciel Filho, P.   +10 more
core   +1 more source

Biomanufacturing of Tomato-Derived Nanovesicles

Foods, 2020
Micro- and nano-sized vesicles (MVs and NVs, respectively) from edible plant resources are gaining increasing interest as green, sustainable, and biocompatible materials for the development of next-generation delivery vectors.
Ramesh Bokka, Anna Paulina Ramos, Immacolata Fiume, Mauro Manno, Samuele Raccosta, Lilla Turiák, Simon Sugár, Giorgia Adamo, Tamás Csizmadia, Gabriella Pocsfalvi   +9 more
doaj   +1 more source