Results 101 to 110 of about 11,629 (239)
In‐Gel Generated Palladium Nanostructures as Bioorthogonal Uncaging Reactors
Advanced NanoBiomed ResearchIn the quest to alleviate the severe side effects of chemotherapy, a promising approach is through prodrugs, an inactivate form of the drug that is administered systemically but activated locally.
Aisling McGuigan +4 more
doaj +1 more source
Biochemistry and Biophysics Reports, 2019 Many biophysical techniques that are available to study the structure, function and dynamics of cellular constituents require modification of the target molecules.
Leonhard Jakob +2 more
doaj +1 more source
Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling
Angewandte Chemie International Edition, EarlyView.Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl +1 more
wiley +1 more source
Cycloadditions of cyclohexynes and cyclopentyne. [PDF]
, 2014 We report the strategic use of cyclohexyne and the more elusive intermediate, cyclopentyne, as a tool for the synthesis of new heterocyclic compounds. Experimental and computational studies of a 3-substituted cyclohexyne are also described.
Garg, Neil K +4 more
core +2 more sources
Bioorthogonal Janus microparticles for photothermal and chemo‐therapy
Smart MedicineBioorthogonal chemistry, recognized as a highly efficient tool in chemical biology, has shown significant value in cancer treatment. The primary objective is to develop efficient delivery strategies to achieve enhanced bioorthogonal drug treatment for ...
Qingfei Zhang +4 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2010 Sialic acids are located at the termini of mammalian cell-surface glycostructures, which participate in essential interaction processes including adhesion of pathogens prior to infection and immunogenicity. Here we present the synthesis and bioorthogonal
Arne Homann +4 more
doaj +1 more source
Teaching old NCATs new tricks: using non-canonical amino acid tagging to study neuronal plasticity [PDF]
, 2013 The non-canonical amino acid labeling techniques BONCAT (bioorthogonal non-canonical amino acid tagging) and FUNCAT (fluorescent non-canonical amino acid tagging) enable the specific identification and visualization of newly synthesized proteins ...
Dieterich, D .C. +2 more
core
Layer-by-layer biofabrication of coronary covered stents with clickable elastin-like recombinamers [PDF]
, 2019 Producción CientíficaCoronary artery disease is the leading cause of death around the world. Endovascular stenting is the preferred treatment option to restore blood flow in the coronary arteries due to the lower perioperative morbidity when compared ...
Fernández Colino, Alicia +7 more
core +2 more sources
Engineering cell surfaces by covalent grafting of synthetic polymers to metabolically-labeled glycans [PDF]
, 2018 Re-engineering mammalian cell surfaces enables modulation of their phenotype, function, and interactions with external markers and may find application in cell-based therapies.
Bailey, Trisha L. +3 more
core +2 more sources
Genetic code expansion for chemosensing and chemical actuation of biological functions
Bulletin of the Korean Chemical Society, EarlyView.Genetic code expansion (GCE) broadens the chemical repertoire for precise control of protein function in biological systems. This review highlights GCE‐based sensing and actuating systems that operate through selective interactions between noncanonical amino acids and chemical triggers.
Jieun Bae, Dong‐Hyun Kim, Minseob Koh
wiley +1 more source