An Efficient Synthesis of 2'-O-(β-D-Ribofuranosyl)biopterin [PDF]
N2-(N,N-Dimethylaminomethylene)-3-[2-(4-nitrophenyl)ethyl]-1',2'-di-O-(trimethylsilyl)biopterin (4) was prepared from biopterin (1a, 86% overall yield) in 5 steps.
Hanaya Tadashi +5 more
doaj +4 more sources
The High Concentration of Biopterin In Breast Milk and It's Absorption During the Neonatal Period [PDF]
Breast milk has been found to contain high levels of biopterin compounds, whose physiological roles have attracted attention through newly discovered functions, particularly. as a cofactor for biosynthesis of nitric oxide.
Iizuka Tadashi +7 more
doaj +2 more sources
The urinary biopterin in autism spectrum disorder [PDF]
The aim of the study was to determine whether biopterin is present in significantly lower quantities in urine samples of patients with autism spectrum disorder (ASD) compared to healthy individuals.
Waligóra Aleksandra +4 more
doaj +2 more sources
Enzymatic Synthesis of Four Stereoisomers of 7-0xo-biopterin and Determination of the Absolute Structure of Ichthyopterin [PDF]
Enzymatic conversion of stereoisomers of biopterin (3a-d) to the 7-oxo-biopterin isomers (4a-d) was performed with a new pterin 7-oxidase extracted from carp skin.
Takikawa Shin Ichiro, Matsuura Sadao
doaj +2 more sources
Late-stage systemic immune effectors in Plasmodium berghei ANKA infection: biopterin and oxidative stress [PDF]
To investigate the involvement of systemic oxidative stress in the pathogenesis of murine cerebral malaria, mice were infected with the Plasmodium berghei (P. berghei) ANKA 6653 strain.
Dogruman-Al Funda +4 more
doaj +2 more sources
Effect of 7,8 -Dihydroneopterin, Biopterin and Isoxanthopterin on Cholesterol and Phospholipid Content and Phospholipid Biosynthesis in Vitro [PDF]
Incorporation of fatty acids into phospholipids has been investigated using samples of rat liver tissue homogenate (Krebs-Ringer-phosphate buffer, pH=7.4, containing 0.3% albumin, fatty acid mixture and glycerol). The addition of 7,8-dihydroneopterin and
Rudzite Vera +4 more
doaj +2 more sources
Serum Biopterin as a Marker of Immune Activation in the Spontaneously Diabetic BB Rat
Tetrahydrobiopterin (BH4), is a pteridine product which is released by rodent macrophages and fibroblasts upon activation by cytokines. It has previously been reported as a potentially useful marker for monitoring immune activation during the prediabetic
Galloway Tamara +4 more
doaj +2 more sources
A systematic review and meta-analysis of pteridines in mild cognitive impairment and Alzheimer’s disease [PDF]
Background Alterations in specific pteridine metabolites, particularly neopterin, biopterin, and tetrahydrobiopterin have been reported in mild cognitive impairment, Alzheimer’s disease, and other types of dementia.
Arduino A. Mangoni, Angelo Zinellu
doaj +2 more sources
Disorders of biopterin metabolism [PDF]
SummaryDefects in the metabolism or regeneration of tetrahydrobiopterin (BH4) were initially discovered in patients with hyperphenylalaninaemia who had progressive neurological deterioration despite optimal metabolic control (malignant hyperphenylalaninaemia).
Nicola Longo
openalex +4 more sources
Immune Stimulation of Interferon-Gamma- and Biopterin Synthesis with Endotoxin in Animal-Experimental Peritonitis [PDF]
As a result to a microhial stimulus different defence systems are activated. Bacterial lipopolysaccharids (endotoxins) can lead to activation of the immune system in which phagocytic cells like macrophages.
Kullich W. +3 more
doaj +2 more sources

