Results 11 to 20 of about 4,698 (199)
Age-Dependent Variation in Blood Biopterin Peaks Following Oral Tetrahydrobiopterin Administration in Phenylketonuria. [PDF]
J Inherit Metab DisABSTRACT The correct diagnosis of tetrahydrobiopterin (BH4, sapropterin dihydrochloride)‐responsive phenylketonuria (PKU) and treatment with BH4 are important for prognosis and quality of life. We examined whether age affects biopterin bioavailability following oral BH4 administration in PKU and whether this influences BH4 responsiveness.
Kitayama K +5 more
europepmc +2 more sources
A Single-Center Retrospective Cohort Study of Biopterin Metabolism Disorders in the United Arab Emirates. [PDF]
JIMD RepABSTRACT Background Tetrahydrobiopterin (BH4) deficiencies comprise a group of five neurometabolic disorders caused by five genetic defects responsible for BH4 biosynthesis and regeneration. Their global prevalence remains unknown, and variance exists among different countries.
Jarrah O, Nouri M, Al Shamsi A.
europepmc +2 more sources
Enhanced Monacolin K Production in Monascus purpureus Via Mutagenesis and Nitrogen Source Optimization. [PDF]
J Basic MicrobiolABSTRACT Monascus fungi are valued for their production of Monacolin K (MK), a bioactive compound with recognized lipid‐lowering and multifunctional properties. To enhance MK yield in solid‐state fermentation, this study combined atmospheric and room‐temperature plasma (ARTP) mutagenesis with L‐arginine supplementation.
Yang C, Yajing Y, Housheng H.
europepmc +2 more sources
Neopterin and biopterin levels and tryptophan degradation in patients with diabetes
Scientific Reports, 2020 This study aimed to evaluate the possible changes of neopterin, biopterin levels and tryptophan degradation in diabetes and to compare the results within diabetes groups and with healthy subjects.
Sinem Gürcü +5 more
semanticscholar +1 more source
The High Concentration of Biopterin In Breast Milk and It's Absorption During the Neonatal Period
Pteridines, 1995 Breast milk has been found to contain high levels of biopterin compounds, whose physiological roles have attracted attention through newly discovered functions, particularly. as a cofactor for biosynthesis of nitric oxide.
Iizuka Tadashi +7 more
doaj +1 more source
Pteridines, 1990 Enzymatic conversion of stereoisomers of biopterin (3a-d) to the 7-oxo-biopterin isomers (4a-d) was performed with a new pterin 7-oxidase extracted from carp skin.
Takikawa Shin Ichiro, Matsuura Sadao
doaj +1 more source
Biopterin responsive phenylalanine hydroxylase deficiency [PDF]
Genetics in Medicine, 2004 Phenylketonuria (PKU) is an autosomal recessive disorder caused by mutations in the phenylalanine hydroxylase (PAH) gene. There have been more than 400 mutations identified in the PAH gene leading to variable degrees of deficiency in PAH activity, and consequently a wide spectrum of clinical severity.
Reuben, Matalon +11 more
openaire +2 more sources
Pteridines, 1995 Treatment of L-biopterin (I) with N,N-dimethyformamide dimethyl- (or diethyl)acetal and then with acetic anhydride in pyridine gave 1',2'-di-O-acetyl-N'-(N,N-dimethylaminomethylene)-L-biopterin (4), which was converted by the Mitsunobu reaction into 3 ...
Hanaya Tadashi +5 more
doaj +1 more source
Metabolomic Analysis of Phytophthora parasitica Growth in the Presence of β-sitosterol Indicates Adaptive Mechanisms Modulated by Sterols. [PDF]
J Basic MicrobiolABSTRACT Phytophthora parasitica is a generalist phytopathogenic oomycete that infects a series of crops with great economic interest, including tomato, tobacco, and citrus species. Sterols are essential lipids in eukaryotic organisms, playing a fundamental role in the structure and function of the cell membrane.
Martins PP +7 more
europepmc +2 more sources
An Efficient Synthesis of 2'-O-(β-D-Ribofuranosyl)biopterin
Pteridines, 2008 N2-(N,N-Dimethylaminomethylene)-3-[2-(4-nitrophenyl)ethyl]-1',2'-di-O-(trimethylsilyl)biopterin (4) was prepared from biopterin (1a, 86% overall yield) in 5 steps.
Hanaya Tadashi +5 more
doaj +1 more source