Exploring the scope of DBU-promoted amidations of 7-carboxymethyl-pterin [PDF]
, 2020 Pteridines are an important heterocycle often used in the development of pharmaceutically relevant compounds, and in the field of supramolecular chemistry.
Bockman, Anna
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First Synthesis of a Representative, Natural Pterin Glycoside: 2’-O-(α-D-Glucopyranosyl)biopterin [PDF]
, 2009 Glycosylation of N(2)-(N,N-dimethylaminomethylene)-1’-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl) ethyl]biopterin (14) with the novel donor 4,6-di-O-acetyl-2,3-di-O-(4-methoxybenzyl)-α-D-glucopyranosyl bromide (19) in the presence of silver triflate and ...
Hanaya, Tadashi +2 more
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Electron paramagnetic resonance characterization of tetrahydrobiopterin radical formation in bacterial nitric oxide synthase compared to mammalian nitric oxide synthase. [PDF]
, 2012 International audienceH(4)B is an essential catalytic cofactor of the mNOSs. It acts as an electron donor and activates the ferrous heme-oxygen complex intermediate during Arg oxidation (first step) and NOHA oxidation (second step) leading to nitric ...
Brunel, Albane +2 more
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Assessment of Metabolic Parameters For Autism Spectrum Disorders [PDF]
, 2009 Autism is a brain development disorder that first appears during infancy or childhood, and generally follows a steady course without remission. Impairments result from maturation-related changes in various systems of the brain.
Ghosh, S +4 more
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Molecular analysis of PKU-associated PAH mutations: a fast and simple genotyping test [PDF]
, 2018 : Neonatal screening for phenylketonuria (PKU, OMIM: 261600) was introduced at the end of the 1960s. We developed a rapid and simple molecular test for the most frequent phenylalanine hydroxylase (PAH, Gene ID: 5053) mutations.
Antonio Angeloni +9 more
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The Leishmania donovani LD1 locus gene ORFG encodes a biopterin transporter (BT1) [PDF]
, 1999 We have previously described two genes, ORFF and ORFG, from the LD1 locus near one telomere of chromosome 35, which are frequently amplified in Leishmania isolates.
Beverley, Stephen M. +7 more
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Synthesis of 6β-N(5)-Methyl-5,6,7,8-tetrahydro-L-biopterin [PDF]
, 2017 Summary 6β-N(5)-methyl-5.6J,8-tetrahydro-L-biopterin·2 HC1. a new derivate of biological interest, was synthesized from 6β-5,6,7,8-tetrahydro-L-biopteril·2 HC1 and characterized.
Bosshard, Rene +2 more
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Disorders of biopterin metabolism [PDF]
Journal of Inherited Metabolic Disease, 2009 SummaryDefects in the metabolism or regeneration of tetrahydrobiopterin (BH4) were initially discovered in patients with hyperphenylalaninaemia who had progressive neurological deterioration despite optimal metabolic control (malignant hyperphenylalaninaemia).
openaire +4 more sources
Tetrahydrobiopterin Deficiency: From Phenotype to Genotype [PDF]
, 2017 As a result of the selective screening worldwide during the last 18 years, approximately 250 patients with tetrahydrobiopterin deficiency were discovered.
Blau, Nenad +3 more
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Isolation and culture of murine bone marrow-derived macrophages for nitric oxide and redox biology [PDF]
, 2020 Macrophages are mononuclear phagocytes derived from haematopoietic progenitors that are widely distributed throughout the body. These cells participate in both innate and adaptive immune responses and lie central to the processes of inflammation ...
Andrew Shaw +37 more
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