Results 121 to 130 of about 71,391 (320)
Electrokinetic Flow Modeling Through Bone Scaffold [PDF]
Fluid flow and mass transfer inside a bioreactor play a pivotal role in growing bone grafts, as cell proliferation is limited by the transport of nutrients and oxygen, as well as the removal of by-products from cells within the scaffold. Traditionally, perfusion bioreactors are used for tissue-engineered bone grafts.
arxiv
Micro-Bioreactor Mimicking a Cellular Environment [PDF]
We report that a cell-sized water droplet (CWD) with a diameter of several tens of microns can serve as a micro-biochemical reactor. Since the droplet inner surface is covered by a phospholipid layer, it provides an environment similar to that in living cells. The CWD is manipulated with laser tweezers and we monitor the time-development of biochemical
arxiv
Fighting Antibiotic Resistance: Insights Into Human Barriers and New Opportunities
Antibiotic resistance is a public health issue leading to the emergence of multi‐resistant bacteria. Human‐dependent factors are now driving the increase of resistance, notably through antibiotic misuse in human and animal health and environmental pollution.
Aubin Pitiot+3 more
wiley +1 more source
Artificial microbial consortia for bioproduction processes
Abstract The application of artificial microbial consortia for biotechnological production processes is an emerging field in research as it offers great potential for the improvement of established as well as the development of novel processes. In this review, we summarize recent highlights in the usage of various microbial consortia for the production
Fabian Mittermeier+6 more
wiley +1 more source
A chemostat model with variable dilution rate due to biofilm growth [PDF]
In many real life applications, a continuous culture bioreactor may cease to function properly due to bioclogging which is typically caused by the microbial overgrowth. This is a problem that has been largely overlooked in the chemostat modeling literature, despite the fact that a number of models explicitly accounted for biofilm development inside the
arxiv
"Oenodynamic": Hydrodynamic of wine swirling [PDF]
A crucial step in wine tasting is the so called swirling, necessary to release the bouquet of the wine: a gentle circular movement of the glass generates a wave propagating along the glass walls, enhancing oxygenation and mixing. Although being used in a large variety of other applications (e.g. cells cultures in orbital shaken bioreactors) this motion
arxiv
Abstract Rationally designed synthetic microbial consortia carry a vast potential for biotechnological applications. The application of such a consortium in a bioprocess, however, requires tight and individual controllability of the involved microbes.
Franziska Kratzl+2 more
wiley +1 more source
Sigma Factors as Potential Targets to Enhance Recombinant Protein Expression
ABSTRACT The transcriptional factors control the expression of many genes and represent an important layer of complexity in cell factories. However, the effect of individual sigma factor deletions from a biomanufacturing perspective has not been addressed. In this contribution, growth, green fluorescence protein (GFP) expression, and oxygen consumption
Laura Pohlen+6 more
wiley +1 more source
Assessing the growth kinetics and stoichiometry of Escherichia coli at the single‐cell level
Abstract Microfluidic cultivation and single‐cell analysis are inherent parts of modern microbial biotechnology and microbiology. However, implementing biochemical engineering principles based on the kinetics and stoichiometry of growth in microscopic spaces remained unattained.
Katharina Smaluch+5 more
wiley +1 more source
Airlift Bioreactors - Bioreactors Design
Producción ...
Guieysse, Benoit+2 more
openaire +1 more source