ABSTRACT Komagataella phaffii, also known as Pichia pastoris, is a powerful host for recombinant protein production, in part due to its exceptionally strong and tightly controlled PAOX1 promoter. Most K. phaffii bioprocesses for recombinant protein production rely on PAOX1 to achieve dynamic control in two‐phase processes.
Shannon M. Hoffman+4 more
wiley +1 more source
Toxicity reduction in continuous, high productivity ethanol fermentation by Parageobacillus thermoglucosidasius using in situ microbubble gas stripping. [PDF]
Ibenegbu C+5 more
europepmc +1 more source
Mass Propagation of Multiple Shoots Using a Large Bioreactor.
Motomu Akita+3 more
openalex +2 more sources
Enrichment of Full AAV2 Using Multicolumn Countercurrent Solvent Gradient Purification (MCSGP)
The multicolumn countercurrent solvent gradient purification (MCSGP) method was evaluated as a method to enhance the separation of empty and full capsids during AAV2 purification. The results demonstrated an enrichment of full AAV2 particles using MCSGP.
Julia M. Müller+9 more
wiley +1 more source
Large-Scale Expansion of Suspension Cells in an Automated Hollow-Fiber Perfusion Bioreactor. [PDF]
Bräuchle E+7 more
europepmc +1 more source
Recovery Rate of Fermented Ethanol by a Stripping Bioreactor
Kazuo Sato+2 more
openalex +2 more sources
Evaluation of hollow fiber bioreactors as an alternative to murine ascites production for small scale monoclonal antibody production [PDF]
Lynn Jackson+3 more
openalex +1 more source
ABSTRACT There is increasing interest in the development of intensified processes that can provide significant reductions in manufacturing costs for monoclonal antibody (mAb) products. This study examines the performance of an integrated membrane process that combines single‐pass tangential flow filtration (SPTFF) with high‐performance countercurrent ...
Mirko Minervini+4 more
wiley +1 more source
Modeling and Feasibility Assessment of Mineral Carbonation Based on Biological pH Swing for Atmospheric CO<sub>2</sub> Removal. [PDF]
Zhang Y+5 more
europepmc +1 more source
Simulation study of the fermentation-process in a stripping bioreactor
Kazuo Sato+2 more
openalex +2 more sources