Mechanistic study of physicochemical and biochemical processes affecting intestinal absorption of the sesquiterpene lactone nobilin from multi-component systems in the Caco-2 model [PDF]
, 2015 The overall aim of this work was to investigate the intestinal absorption of the sesquiterpene lactone nobilin from the flowers of Anthemis nobilis L.
Thormann, U.
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Concentration and Composition Dependent Aggregation of Pluronic- and Poly-(2-Oxazolin)-Efavirenz Formulations in Biorelevant Media [PDF]
, 2021 Interactions of intestinal fluids with polymer excipients, drugs and their formulations are not fully understood. Here, diffusion ordered spectroscopy (DOSY) and nuclear Overhauser effect spectroscopy (NOESY), complemented by cryo-TEM were employed to ...
Lorenz, Meinel +9 more
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In vitro simulation of distribution processes following intramuscular injection
Current Directions in Biomedical Engineering, 2016 There is an urgent need for in vitro dissolution test setups for intramuscularly applied dosage forms. Especially biorelevant methods are needed to predict the in vivo behavior of newly developed dosage forms in a realistic way.
Probst Mareike +3 more
doaj +1 more source
MPTHub: An Open-Source Software for Characterizing the Transport of Particles in Biorelevant Media
Nanomaterials, 2022 The study of particle transport in different environments plays an essential role in understanding interactions with humans and other living organisms.
Leandro Gabriel +4 more
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A REVIEW ON DEVELOPMENT OF BIORELEVANT DISSOLUTION MEDIUM [PDF]
, 2014 Dissolution testing is a valuable tool that provides key information about bioavailability or bioequivalency as well as batch to batch consistency of drug.
Bhagat, Nitin B
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Superiority of Mesoporous Silica-Based Amorphous Formulations over Spray-Dried Solid Dispersions
Pharmaceutics, 2022 The aim of this study was to compare the performance of two amorphous formulation strategies: mesoporous silica via solvent impregnation, and solid dispersions by spray drying. Poorly soluble fenofibrate was chosen as the model drug compound.
Hongwei Zhang +5 more
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, 2021 Biorelevant dissolution media are aqueous solutions or suspensions whose composition and physicochemical characteristics closely resemble human fluids found along the different portions of the gastrointestinal tract, developed to study the solubility and/
Ruiz, María Esperanza +3 more
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Angewandte Chemie, EarlyView.Catalytic strain‐release ring opening and functionalizations of 1‐azabicyclo[1.1.0]butanes (ABBs) represent a promising strategy for accessing diverse azetidine products. These transformations proceed via polar pathways, radical pathways, and hybrid mechanisms that combine both.
James Shao‐Jiun Yang +1 more
wiley +2 more sources
Organics, 2021 A convenient synthetic approach to previously unknown NH-iminophosphonates bearing 2-, 3-, and 4-pyridyldifluoromethyl groups at the imine carbon atom was developed.
Oksana M. Shavrina +4 more
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Numerical prediction of drug release from polyurethane samples combining kinetic model developed by experimental data [PDF]
E3S Web of Conferences, 2021 With the aim of optimizing Drug Eluting Stents (DES), particular attention has been laid on computational methods of controlling the drug release profile among researchers.
Song Jianfei +5 more
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