Results 71 to 80 of about 6,100 (218)
Synthesis and diverse biological activity profile of triethylammonium isatin-3-hydrazones
ADMET and DMPK, 2022 A series of biorelevant triethylammonium isatin hydrazones containing various substituents in the aromatic fragment have been synthesized. Their structure and composition were confirmed by NMR- and IR-spectroscopies, mass-spectrometry and elemental ...
Andrei Bogdanov +8 more
doaj +1 more source
ChemistryEurope, Volume 4, Issue 4, April 2026.Ni(0)‐catalyzed [2 + 2 + 2] cycloadditions of linked bisdiynes with diarylacetylenes generate highly fluorescent D‐π‐A‐π‐D bis(arylethynyl)indane dyes. They bind strongly to ds‐DNA and ‐RNA leading to significant fluorescence quenching, are nontoxic toward human cell lines, and have potential as multimodal fluorescence, CD, and Raman probes for ...
Robert Ricker +15 more
wiley +1 more source
Study of the impact of different salts on the intrinsic dissolution rate of pharmaceutical compounds [PDF]
, 2017 The intrinsic dissolution rate (IDR) of a free base and its four salts were investigated with the aim of selecting the salt with the best dissolution performance.
Box, Karl +3 more
core +1 more source
A Unified Mechanism on the Formation of Acenes, Helicenes, and Phenacenes in the Gas Phase. [PDF]
, 2020 A unified low-temperature reaction mechanism on the formation of acenes, phenacenes, and helicenes-polycyclic aromatic hydrocarbons (PAHs) that are distinct via the linear, zigzag, and ortho-condensed arrangements of fused benzene rings-is revealed. This
Ablikim, Utuq +8 more
core +1 more source
Food Science &Nutrition, Volume 14, Issue 4, April 2026.Medium‐chain diacylglycerols were incorporated into fully hydrogenated palm kernel oil stearin (FHPKS) to regulate crystallization behavior and melt–dispersion performance. Low DAG levels (5%–10%) promoted β′‐rich crystal networks and improved thermal responsiveness, establishing a structure–property framework for designing functional lipid bases ...
Jun Jin, Mingxuan Fang, Siyu Zhang
wiley +1 more source
Pharmaceutics, 2019 Nifedipine (NIF) is a 1,4-dihydropyridine-based calcium channel blocker with poor solubility, whose bioavailability is highly dependent on the type of formulation.
Athanasios Mantas, Albert Mihranyan
doaj +1 more source
The Coordination Chemistry of Bio-Relevant Ligands and Their Magnesium Complexes
Molecules, 2020 The coordination chemistry of magnesium (Mg2+) was extensively explored. More recently; magnesium; which plays a role in over 80% of metabolic functions and governs over 350 enzymatic processes; is becoming increasingly linked to chronic disease ...
Derek R. Case +2 more
doaj +1 more source
Organic and Metallacages for Chemical Sensing: Progress in Water‐Compatible Systems
Advanced Sensor Research, Volume 5, Issue 3, March 2026.Supramolecular cages function as three‐dimensional receptors for selective molecular recognition and sensing, and this review outlines design principles for water‐stable architectures, key analyte‐ and medium‐dependent challenges, recent water‐compatible examples (including polymer‐integrated systems), and future opportunities for cage‐based ...
Rabia Zahid +4 more
wiley +1 more source
ADMET and DMPKBackground and purpose: The evaluation of micellization parameters of surfactants that aggregate gradually, such as bile salts, is not trivial. In this work, different probes and data treatment models are tested to set up an analytical method based on ...
Susana Amézqueta +3 more
doaj +1 more source
Design of a Reconfigurable Microfluidic System Enabled by Magnetic Miniature Robots
Advanced Intelligent Systems, Volume 8, Issue 3, March 2026.Magnetic miniature robots are integrated into microfluidic chips to achieve real‐time reconfiguration. By external magnetic actuation, the robots perform sorting, mixing, flow regulation, and bubble removal on demand. This versatile platform eliminates the need for complex on‐chip hardware and enables adaptive control for biological and chemical ...
Yuanhe Chen +3 more
wiley +1 more source