Journal of Pharmacy & Pharmaceutical Sciences, 2008 - Purpose: Unlike orthodox medicines, specific guidelines for dissolution testing of complementary/alternate (CAMs) and traditional medicines (TMs) have not been developed nor is dissolution testing a requirement for the quality control of such products.
Vipin Devi Prasad Nair, Isadore Kanfer
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Analytical tools for the physicochemical profiling of drug candidates to predict absorption/distribution [PDF]
, 2018 The measurement of physicochemical properties at an early phase of drug discovery and development is crucial to reduce attrition rates due to poor biopharmaceutical properties.
Bard, Bruno +5 more
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Optimização de um método de avaliação simultânea da dissolução e permeabilidade de fármacos [PDF]
, 2008 Englobado na temática do desenvolvimento de métodos in vitro para avaliação da biodisponibilidade de fármacos, este trabalho de investigação teve como objectivo a optimização de um método para avaliar em simultâneo a dissolução e permeabilidade de ...
Ferreira, Pedro +4 more
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Antioxidant activity and cytotoxicity of solubilized C60 and its conjugates with butylated hydroxytoluene [PDF]
, 2011 It has been described that fullerenes (C60) present interesting properties with potential application in clinical conditions related to oxidative stress. One of the most prominent features of fullerenes is the ability to quench free radicals.
Caetano, Liliana Aranha +4 more
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Разработка и регистрация лекарственных средствThe use of biorelevant dissolution media makes it possible to reproduce conditions as in the human gastrointestinal tract. This expands the capabilities of laboratories involved in the analysis of solid dosage forms and allows obtaining physiologically ...
article Editorial
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A biorelevant test for tablets glycine sublingual in the «simulated saliva» dissolution medium
Разработка и регистрация лекарственных средствIntroduction. Biorelevant dissolution media reconstitute the composition of the contents of the gastrointestinal tract. They are used as dissolution media in the evaluation of dissolution profiles of different dosage forms.
S. D. Kulikova +5 more
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The interplay of poorly soluble drugs in dissolution from amorphous solid dispersions
International Journal of Pharmaceutics: XIn recent years, the application of fixed dose combinations of antiretroviral drugs in HIV therapy has been established. Despite numerous therapeutic benefits, this approach poses several challenges for the formulation development especially when poorly ...
Marcel Kokott +2 more
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Johanniskraut - von Inhaltsstoffen und anderen Unwägbarkeiten [PDF]
, 2009 Die Depression gehört zu den häufigsten Volkskrankheiten. Derzeit sind rund vier Millionen Deutsche an einer behandlungsbedürftigen Depression erkrankt.
Schubert-Zsilavecz, Manfred (Prof. Dr.) +1 more
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Use of PBPK Modeling To Evaluate the Performance of Dissolv It, a Biorelevant Dissolution Assay for Orally Inhaled Drug Products. [PDF]
Mol Pharm, 2019 Hassoun M +11 more
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Development of a Discriminative and Biorelevant Dissolution Test Method for Atorvastatin/Fenofibrate Combination with Appliance of Derivative Spectrophotometry. [PDF]
Turk J Pharm Sci, 2019 Anumolu PD +5 more
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