Results 111 to 120 of about 1,723 (196)

Dissolution testing of modified release products with biorelevant media: An OrBiTo ring study using the USP apparatus III and IV

, 2020
During the OrBiTo project, our knowledge on the gastrointestinal environment has improved substantially and biorelevant media composition have been refined.
Williams, J., Tomaszewska, I., Karkossa, F., Vertzoni, M., Andreas, C.J., Rosenblatt, K., Winge, F., Klein, S., Karlsson, E., Dressman, J., Mistry, N., McAllister, M., Etherson, K., Smith, K.L., Hanley, S., Reppas, C., Vrettos, N.-N., Maier, G.-M., Schäfer, K.J., Miyaji, Y., Brown, J.   +20 more
core  

Development of a Discriminative and Biorelevant Dissolution Test Method for Atorvastatin/Fenofibrate Combination with Appliance of Derivative Spectrophotometry. [PDF]

Turk J Pharm Sci, 2019
Anumolu PD, Gurrala S, Venkata Satya SC, Polisetty SV, Ravindran A, Achanta R.   +5 more
europepmc   +1 more source

Biorelevant Dissolution Tests with the Flow-Through Apparatus?

Dissolution Technologies, 2000
Nicolaides, E., Hempenstall, J.M., Reppas, C.   +2 more
openaire   +2 more sources

Overcoming drug impurity challenges in amorphous solid dispersion with rational development of biorelevant dissolution-permeation method

Hot-melt extrusion is often used to prepare amorphous solid dispersion to overcome low drug solubility and enhance bio-performance of the formulation. Due to the uniqueness of each drug - polymer combination and its physico-chemical properties, setting ...
Janković, Biljana, Jeraj, Žiga, Zajc-Kreft, Katarina, Jakasanovski, Ognen, Puž, Vid, Berginc, Katja, Huzjak, Tilen   +6 more
core   +1 more source

Formulating abiraterone acetate-HPMCAS-based amorphous solid dispersions: insights into in vitro and biorelevant dissolution assessments and pharmacokinetic evaluations. [PDF]

RSC Adv
Choudhari M, Damle S, Saha RN, Dubey SK, Singhvi G.   +4 more
europepmc   +1 more source

Role of Biorelevant Dissolution Media in the Selection of Optimal Salt Forms of Oral Drugs: Maximizing the Gastrointestinal Solubility and in Vitro Activity of the Antimicrobial Molecule, Clofazimine. [PDF]

ACS Omega, 2017
Bannigan P, Durack E, Madden C, Lusi M, Hudson SP.   +4 more
europepmc   +1 more source

Development of a biorelevant methodology for drug release in the mouth [PDF]

The oral route is the most popular and convenient route for drug administration. There are a growing number of alternative solid oral dosage forms that have been developed for more specialised drug delivery compared to monolithic solid oral dosage forms.
Ali, Joseph
core  

Development of biorelevant simulated salivary fluids for application in dissolution testing

, 2017
Conventional adult dosage forms such as tablets and capsules are often not suitable for the paediatric and geriatric population due to either swallowing difficulties or a requirement for tailored dosing to meet individual needs. Alternative oral formulations such as orally disintegrating tablets (ODTs) are available; however these usually require the ...
openaire   +1 more source

Application of New Approach Methodologies to Improve Oral Biopharmaceutic Assessments. [PDF]

Pharmaceutics
García MA, Cabrera-Pérez MÁ, González PM, Aceituno A, Hachim D.   +4 more
europepmc   +1 more source

Development of in vitro-in vivo correlation for establishing patient-centric quality standards of dissolution for lamotrigine extended-release tablets. [PDF]

Eur J Pharm Biopharm
Zidan A, Siddique AB, Shaklah M, Anand O, O'Connor T, Ashraf M.   +5 more
europepmc   +1 more source