Results 111 to 120 of about 224,448 (162)

Application of biorelevant dissolution tests to the prediction of in vivo performance of diclofenac sodium from an oral modified-release pellet dosage form

, 2009
In vitro biorelevant dissolution tests enabling the prediction of in vivo performance of an oral modified-release (MR) dosage form were developed in this study.
Ronda, E., Mattavelli, V., Vertzoni, M., Dressman, J.B., Jantratid, E., De Maio, V.   +5 more
core  

Improvement of XZP8257 Dissolution Properties Through Amorphous and Mixed-Phase Precipitate Formation in Biorelevant Media. [PDF]

Biopharm Drug Dispos
Zhang M, Zhang S, Wu B, Zhang Z, Hu Q, Wang L, Liu D.   +6 more
europepmc   +1 more source

Integrating Experimental Physicochemical Data with PBPK Modeling to Guide the Translational Development of the Antifungal 1,3,4-Oxadiazole Derivative LMM6. [PDF]

ACS Omega
Piai JMB, Lippa VNM, Caleffi-Marchesini ER, Borghi Pangoni FB, Felipe MS, Kioshima ES, Diniz A.   +6 more
europepmc   +1 more source

Role of Biorelevant Dissolution Media in the Selection of Optimal Salt Forms of Oral Drugs: Maximizing the Gastrointestinal Solubility and in Vitro Activity of the Antimicrobial Molecule, Clofazimine. [PDF]

ACS Omega, 2017
Bannigan P, Durack E, Madden C, Lusi M, Hudson SP.   +4 more
europepmc   +1 more source

Application of New Approach Methodologies to Improve Oral Biopharmaceutic Assessments. [PDF]

Pharmaceutics
García MA, Cabrera-Pérez MÁ, González PM, Aceituno A, Hachim D.   +4 more
europepmc   +1 more source

An Overview of In Vitro Release Methods for Long-Acting Injectable Products Based on PLGA. [PDF]

Methods Protoc
Lusina Kregar M, Krtalić I, Šagud I.
europepmc   +1 more source

A PBPK-VBE approach for bioequivalence extrapolation of senaparib capsule strengths in the context of nonlinear pharmacokinetics: bridging from the clinical starting dose to the linear pharmacokinetic range. [PDF]

Front Pharmacol
Wu X, Wang Z, He Y, Wu K, Liu B, Ma N, Cai S, Xu C, Xu Y, Zhao S, Wang H.   +10 more
europepmc   +1 more source

Chromatographic Characterization of Nasal and Inhalation Drug Products: A Review of Liquid Chromatography Strategies for Formulation Assessment, Particle Size Correlation, and In Vitro Performance Testing. [PDF]

Biomed Chromatogr
Madamsetti N, Aele M, Godishala V, Velidandi A.   +3 more
europepmc   +1 more source

Development of in vitro-in vivo correlation for establishing patient-centric quality standards of dissolution for lamotrigine extended-release tablets. [PDF]

Eur J Pharm Biopharm
Zidan A, Siddique AB, Shaklah M, Anand O, O'Connor T, Ashraf M.   +5 more
europepmc   +1 more source

Physiologically Based Biopharmaceutics Modelling-Best Scientific Practices to Define Drug Product Performance, Latest Regulatory and Industry Perspectives: Workshop Summary Report. [PDF]

Pharmaceutics
McAllister M, Mistry N, Pepin X, Cole S, Tannergren C, Stamatopoulos K, Engman H, Moir A, Litou C, Gavins F, Arora S, Malamatari M, Guimarães M, Ravi A, Fotaki N, Dodd L, Holte Ø, Butler J, Dickinson PA, Popkin M, Butler A, NiOgain O, Holmstock N, Mackie C.   +23 more
europepmc   +1 more source