Results 131 to 140 of about 1,723 (196)

Bioavailability Enhancement and Polymorphic Stabilization of One BCS Class IV Metastable Drug Through Novel Formulation Approach. [PDF]

Turk J Pharm Sci
Panda R, Lankalapalli S.
europepmc   +1 more source

Development, Optimization, and Evaluation of Nano Self-Emulsifying Drug Delivery System Formulation Platform for Oral Bioavailability Enhancement of Sulfasalazine and Disulfiram in Lung Cancer Chemoprevention. [PDF]

Pharm Res
Desai P, Bang K, Chowdhury MRH, Wang ZK, Wang J, Prabhu S, Liang X, Kassie F.   +7 more
europepmc   +1 more source

Advances in Physiologically Based Pharmacokinetic (PBPK) Modeling and its Regulatory Utility to Support Oral Drug Product Development and Harmonization. [PDF]

Pharm Res
Cheng YH, Thomas S, Tsang YC, Almeida S, Ashraf M, Fotaki N, Heimbach T, Patel N, Shah H, Jiang X, Kim MJ, Moody R, Rostami-Hodjegan A, Singh R, Zhao L, Babiskin A, Wu F.   +16 more
europepmc   +1 more source

Correlation Between Dissolution Profiles of Salt-Form Drugs in Biorelevant Bicarbonate Buffer and Oral Drug Absorption: Importance of Dose/ Fluid Volume Ratio. [PDF]

Pharm Res
Tarumi Y, Higashiguchi Y, Sugano K.
europepmc   +1 more source

Integrating In Vitro Dissolution and Physiologically Based Pharmacokinetic Modeling for Generic Drug Development: Evaluation of Amorphous Solid Dispersion Formulations for Tacrolimus. [PDF]

Pharmaceutics
Karakitsios E, Angelerou MF, Kapralos I, Tsakiridou G, Kalantzi L, Dokoumetzidis A.   +5 more
europepmc   +1 more source

Pre-Formulation Studies of Lipid-Based Formulation Approach for a Poorly Water-Soluble Biopharmaceutics Classification System Class II Model Drug: Bosentan. [PDF]

Turk J Pharm Sci
Yılmaz Usta D, Teksin ZŞ.
europepmc   +1 more source

Evaluation of USP 3 Apparatus to Develop Biopredictive Fasted and Fed Dissolution Methods for Extended-Release Desvenlafaxine Succinate Tablets. [PDF]

ACS Omega
Carapeto GV, Nunes BC, Duque MD, Issa MG, Ferraz HG.   +4 more
europepmc   +1 more source

Advancing the Harmonization of Biopredictive Methodologies through the Product Quality Research Institute (PQRI) Consortium: Biopredictive Dissolution of Dipyridamole Tablets. [PDF]

Mol Pharm
Tsume Y, Ashworth L, Bermejo Sanz M, Cicale V, Dressman J, Fushimi M, Gonzalez-Alvarez I, Haung PS, Jankovsky C, Liu X, Lu X, Matsui K, Patel S, Ruiz-Picazo A, Sun CC, Thakral N, Zöller L.   +16 more
europepmc   +1 more source

Unlocking the potential of alkaline polymethacrylates via ionic crosslinking in amorphous solid dispersions. [PDF]

Int J Pharm X
Mild L, Stakemeier A, Nguyen Thi MN, Wagner KG.   +3 more
europepmc   +1 more source

Key Factors for Improving Predictive Accuracy and Avoiding Overparameterization of the PBPK Absorption Model in Food Effect Studies of Weakly Basic Water-Insoluble Compounds in Immediate Release Formulations. [PDF]

Pharmaceutics
Zhang M, Zhang S, Wang L, Zhang Z, Hu Q, Liu D.   +5 more
europepmc   +1 more source