Results 51 to 60 of about 224,448 (162)
Pharmaceutics, 2022 A webinar series that was organised by the Academy of Pharmaceutical Sciences Biopharmaceutics focus group in 2021 focused on the challenges of developing clinically relevant dissolution specifications (CRDSs) for oral drug products.
Mark McAllister +20 more
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Biorelevant drug release of Metformin dosage forms using complementary in vitro tools
British Journal of Pharmacy, 2017 Drug release from immediate release (IR) and extended release (ER) metformin products was investigated using the Dow Chemical Company’s FloVitroTM biorelevant dissolution instrument.
Karl Box, Patrick O'Dwyer, Hayley Watson
doaj +1 more source
Journal of Pharmacy & Pharmaceutical Sciences, 2017 Purpose: A variety of fixed-dose combination products is used in the therapy of Parkinson Disease. However, to date a proper analytical method applicable for comparative screening of different antiparkinson products was not available.
Erik Wollmer, Sandra Klein
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Advanced Science, Volume 13, Issue 36, 29 June 2026.The action spectrum of a tailored azobenzene is shifted toward bio‐optical window through the chemical modification of its singlet and triplet energy levels. Consequently, the bidirectional photo‐switching of azobenzene in physiological conditions is achieved when excited by red and far‐red light, which offers greater tissue penetration.
Mila Miroshnichenko +11 more
wiley +1 more source
Development of biorelevant media and dissolution tests for gastrointestinal disease states
, 2022 Standard biorelevant media reflect the average gastrointestinal (GI) physiology in healthy volunteers. The use of biorelevant media in in vitro experiments has become an important strategy to predict drug behaviour in vivo and is often combined with in
Šegregur, Domagoj
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THE FEATURES OF THE PREDICTIVE DISSOLUTION TESTING (REVIEW)
Разработка и регистрация лекарственных средств, 2019 Dissolution test plays an important role at different levels of the development and manufacturing drugs as one of the major quality control tools and an integral part of In vitro tests in the study of drug release from the developed dosage forms. Article
R. I. Moustafine +2 more
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AAPS Open, 2017 Biorelevant dissolution is an indispensable tool utilized during formulation development and optimization for the prediction of in vivo bioavailability of pharmaceutical agents.
Michael M. Puppolo +6 more
doaj +1 more source
ChemMedChem, Volume 21, Issue 9, 14 May 2026.From modular COF design to biomedical translation, this Review maps how linkage chemistry, topology, pore environment, and particle engineering govern bioperformance, therapeutic and diagnostic function, safety, and clinical readiness. Covalent organic frameworks (COFs) are a versatile class of crystalline porous materials with growing potential in ...
Julia Kolodziejczyk +1 more
wiley +1 more source
Comparison Of Dissolution Profiles Of Commercially Available Lamivudine Tablets
, 2015 The aim of this study was to investigate the influence of dissolution medium on the in vitro release of lamivudine (100 mg) from four commercially available lamivudine tablets (one reference and three generic). Three different buffer solutions (pH 1.2, 4.
Ozturk, Naile +2 more
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BIORELEVANT DISSOLUTION MEDIA: ITS CURRENT STATUS AND FUTUTRE PERSPECTIVES [PDF]
The landscape of dissolution media has been dynamically evolving with newer drugs entering the market among which most of them are either BCS class II or BCS class IV drugs exhibiting poor solubility.
Mehta, Tejal +2 more
core +1 more source