Results 51 to 60 of about 379,309 (342)

Complex regulation of the aflatoxin biosynthesis gene cluster of Aspergillus flavus in relation to various combinations of water activity and temperature [PDF]

open access: yes, 2009
A microarray analysis was performed to study the effect of varying combinations of water activity and temperature on the activation of aflatoxin biosynthesis genes in Aspergillus flavus grown on YES medium. Generally A.
Abdel-Hadi, Ahmed   +3 more
core   +1 more source

Characterization of the depsidone gene cluster reveals etherification, decarboxylation and multiple halogenations as tailoring steps in depsidone assembly

open access: yesActa Pharmaceutica Sinica B, 2023
Depsides and depsidones have attracted attention for biosynthetic studies due to their broad biological activities and structural diversity. Previous structure‒activity relationships indicated that triple halogenated depsidones display the best anti ...
Jiafan Yang   +4 more
doaj   +1 more source

Dithiolopyrrolone Natural Products : Isolation, Synthesis and Biosynthesis [PDF]

open access: yes, 2013
Peer reviewedPublisher ...
Deng, Hai   +3 more
core   +2 more sources

The ADEP Biosynthetic Gene Cluster in Streptomyces hawaiiensis NRRL 15010 Reveals an Accessory clpP Gene as a Novel Antibiotic Resistance Factor

open access: yesApplied and Environmental Microbiology, 2019
Antibiotic acyldepsipeptides (ADEPs) represent a promising new class of potent antibiotics and, at the same time, are valuable tools to study the molecular functioning of their target, ClpP, the proteolytic core of the bacterial caseinolytic protease ...
Dhana Thomy   +7 more
semanticscholar   +1 more source

Genetic and functional characterization of the gene cluster directing the biosynthesis of putisolvin I and II in Pseudomonas putida strain PCL1445 [PDF]

open access: yes, 2008
Pseudomonas putida PCL1445 secretes two cyclic lipopeptides, putisolvin I and putisolvin II, which possess a surface-tension-reducing ability, and are able to inhibit biofilm formation and to break down biofilms of Pseudomonas species including ...
Bloemberg, G.V.   +3 more
core   +2 more sources

Direct Pathway Cloning Combined with Sequence- and Ligation-Independent Cloning for Fast Biosynthetic Gene Cluster Refactoring and Heterologous Expression.

open access: yesACS Synthetic Biology, 2018
The need  for new pharmacological lead structures, especially against drug resistances, has led to a surge in natural product research and discovery. New biosynthetic gene cluster capturing methods to efficiently clone and heterologously express natural ...
P. D’Agostino, T. Gulder
semanticscholar   +1 more source

Survey of Biosynthetic Gene Clusters from Sequenced Myxobacteria Reveals Unexplored Biosynthetic Potential [PDF]

open access: yesMicroorganisms, 2019
Coinciding with the increase in sequenced bacteria, mining of bacterial genomes for biosynthetic gene clusters (BGCs) has become a critical component of natural product discovery. The order Myxococcales, a reputable source of biologically active secondary metabolites, spans three suborders which all include natural product producing representatives ...
Katherine Gregory   +4 more
openaire   +3 more sources

Deciphering the Anti-Aflatoxinogenic Properties of Eugenol Using a Large-Scale q-PCR Approach [PDF]

open access: yes, 2016
Produced by several species of Aspergillus, Aflatoxin B1 (AFB1) is a carcinogenic mycotoxin contaminating many crops worldwide. The utilization of fungicides is currently one of the most common methods; nevertheless, their use is not environmentally or ...
Atoui, Ali   +9 more
core   +3 more sources

Comparative Genomics among Closely Related Streptomyces Strains Revealed Specialized Metabolite Biosynthetic Gene Cluster Diversity

open access: yesAntibiotics, 2018
Specialized metabolites are of great interest due to their possible industrial and clinical applications. The increasing number of antimicrobial resistant infectious agents is a major health threat and therefore, the discovery of chemical diversity and ...
C. M. Vicente   +8 more
semanticscholar   +1 more source

Marine Microbial-Derived Resource Exploration: Uncovering the Hidden Potential of Marine Carotenoids

open access: yesMarine Drugs, 2022
Microbes in marine ecosystems are known to produce secondary metabolites. One of which are carotenoids, which have numerous industrial applications, hence their demand will continue to grow.
Ray Steven   +12 more
doaj   +1 more source

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