Results 21 to 30 of about 1,441,063 (301)
Heliyon, 2023 Improved biosynthesis of commercially and pharmacologically relevant phytometabolites through genetic and metabolic engineering is a lucrative strategy for crop improvement.
Sonia Gandhi +2 more
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Unusual free oligosaccharides in human bovine and caprine milk
Scientific Reports, 2022 Free oligosaccharides are abundant macronutrients in milk and involved in prebiotic functions and antiadhesive binding of viruses and pathogenic bacteria to colonocytes.
Wei-Chien Weng +8 more
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Microbiology Spectrum, 2023 Many bacterial surface proteins and carbohydrates are modified with phosphorylcholine (ChoP), which contributes to host mimicry and can also promote colonization and survival in the host. However, the ChoP biosynthetic pathways that are used in bacterial
Yuan Zhang +3 more
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A biosynthetic pathway for anandamide [PDF]
Proceedings of the National Academy of Sciences, 2006 The endocannabinoid arachidonoyl ethanolamine (anandamide) is a lipid transmitter synthesized and released “on demand” by neurons in the brain. Anandamide is also generated by macrophages where its endotoxin (LPS)-induced synthesis has been implicated in the hypotension of septic shock and advanced liver cirrhosis.
Jie, Liu +10 more
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Identification of novel high mannose N-glycan isomers undescribed by current multicellular eukaryotic biosynthetic pathways [PDF]
, 2022 N-linked glycosylation is one of the most important post-translational modifications of proteins. Current knowledge of multicellular eukaryote N-glycan biosynthesis suggests high mannose N-glycans are generated in the endoplasmic reticulum and Golgi ...
Charles Pin-Kuang, Lai +6 more
core +1 more source
Antibiotics ‐ cloning of biosynthetic pathways [PDF]
FEBS Letters, 1990 Biosynthetic pathways leading to antibiotics have often been found to be clustered, and new organizational forms of multifunctional enzymes have been discovered. Such polyenzymes accomplish the synthesis of complex metabolites such as peptides or polyketides by a sequence of enzymatic reactions.
Kleinkauf, Horst, von Döhren, Hans
openaire +2 more sources
Shared PKS Module in Biosynthesis of Synergistic Laxaphycins
Frontiers in Microbiology, 2020 Cyanobacteria produce a wide range of lipopeptides that exhibit potent membrane-disrupting activities. Laxaphycins consist of two families of structurally distinct macrocyclic lipopeptides that act in a synergistic manner to produce antifungal and ...
Lassi Matti Petteri Heinilä +5 more
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Using Gene Expression to Study Specialized Metabolism—A Practical Guide
Frontiers in Plant Science, 2021 Plants produce a vast array of chemical compounds that we use as medicines and flavors, but these compounds’ biosynthetic pathways are still poorly understood.
Riccardo Delli-Ponti +2 more
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Alternative sigma factor over-expression enables heterologous expression of a type II polyketide biosynthetic pathway in Escherichia coli. [PDF]
PLoS ONE, 2013 BACKGROUND: Heterologous expression of bacterial biosynthetic gene clusters is currently an indispensable tool for characterizing biosynthetic pathways.
David Cole Stevens +5 more
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Deep learning driven biosynthetic pathways navigation for natural products with BioNavi-NP
, 2022 The complete biosynthetic pathways are unknown for most natural products (NPs), it is thus valuable to make computer-aided bio-retrosynthesis predictions.
Zheng, Shuangjia +7 more
core +1 more source