Results 231 to 240 of about 164,185 (363)

Transcriptional insights into aflatoxin B1 induced hepatotoxicity and comparative effects of medicinal herbs in pigs. [PDF]

BMC Vet Res
Nalpadan AA, Reyer H, Oster M, Trakooljul N, Ponsuksili S, Kozera W, Karpiesiuk K, Kępka-Borkowska K, Chałaśkiewicz K, Pierzchała M, Taniguchi H, Lepczyński A, Ślaska B, Asediya V, Pareek CS, Wimmers K.   +15 more
europepmc   +1 more source

Elevating Circulating L‐Kynurenine Promotes Frailty in Aging Mice

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background L‐Kynurenine (L‐Kyn), a product of tryptophan catabolism, increases with age and has been associated with reduced physical function and increased frailty in humans. Robustly expressed in skeletal muscle, kynurenine aminotransferases (KATs) degrade L‐Kyn into kynurenic acid and are regulated by the transcriptional co‐regulator ...
Mia Y. Kawaida, Abigail L. Tice, Samuel Alvarez, Jacob A. Lackey, Benjamin Izaguirre, Qingping Yang, Lan Wei‐LaPierre, Russell T. Hepple, Terence E. Ryan   +8 more
wiley   +1 more source

Deciphering the constraints of pure bacterial strains for the complete catabolism of sulfamethoxazole: A proteomic and kinetic study. [PDF]

Biodegradation
Lopez Gordillo AP, Trueba-Santiso A, Smith KEC, Schäffer A, Lema JM.   +4 more
europepmc   +1 more source

Biotransformation of Cobicistat: Metabolic Pathways and Enzymes

, 2016
Pengcheng Wang, Amina I. Shehu, Ke Liu, Jie Lu, Xiaochao Ma   +4 more
openalex   +2 more sources

Herbicide toxicity to Nitrospirillum amazonense: assessing bacterial survival and microbial functionality

Pest Management Science, Volume 82, Issue 2, Page 1842-1852, February 2026.
Herbicides elicit a spectrum of responses in Nitrospirillum amazonense, ranging from the stimulation of metabolic functions (biological nitrogen fixation, IAA production) to significant growth inhibition and acute toxicity. Abstract BACKGROUND Herbicides can exert significant toxicity on nontarget organisms, including plant growth‐promoting bacteria ...
Luana Carolina Gomes Jonck, Patrícia Andrea Monquero, Márcia Maria Rosa Magri, Carina de Fátima Felippe   +3 more
wiley   +1 more source

Biotransformation of Pesticides across Biological Systems: Molecular Mechanisms, Omics Insights, and Biotechnological Advances for Environmental Sustainability. [PDF]

ACS Omega
Basapuram G, Dutta A, Duttagupta S.
europepmc   +1 more source

Beyond the Michaelis–Menten: Evaluation of a tQSSA‐Based IVIVE Approach for Predicting In Vivo Intrinsic Clearance From Hepatocyte Assays

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT The classical Michaelis–Menten model, under the standard quasi‐steady‐state approximation (sQSSA), is widely used in in vitro‐in vivo extrapolation (IVIVE) studies using hepatocyte or human liver microsomal (HLM) assays to predict intrinsic hepatic clearance (Clint,vitro$$ {\mathrm{Cl}}_{\operatorname{int},\mathrm{vitro}} $$).
Ngoc‐Anh Thi Vu, Yun Min Song, Sang Kyum Kim, Hwi‐yeol Yun, Soyoung Lee, Jae Kyoung Kim, Jung‐woo Chae   +6 more
wiley   +1 more source

Toxicokinetics and tissue-specific biotransformation of modified mycotoxin zearalenone-14-glucoside (ZEN-14-G) in broilers following oral administration. [PDF]

Poult Sci
Hamada O, Sun H, Pan X, Suo D, Fan X, Song Z.   +5 more
europepmc   +1 more source

Anaerobic Biotransformation ofN-oxide Containing Aromatic Heterocycles by Bovine Ruminal Fluid

, 2013
Victoria Cerecetto, Florencia Diaz-Viraqué, Ignacio Irazoqui, Alfonso Rodríguez, Cecilia Cajarville, José Luis Repetto, María Laura Lavaggi, Mercedes González, Hugo Cerecetto   +8 more
openalex   +1 more source

Yeast‐Based Biotechnology for Civilian Security

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Yeasts constitute robust and versatile eukaryotic platforms for biotechnological applications relevant to civilian security. Both native and genetically engineered yeast systems enable sensitive detection of chemical and biological hazards, effective removal of metals and organic pollutants, and detoxification of mycotoxins.
Justyna Ruchała, Roksolana Vasylyshyn, Maciej Wnuk   +2 more
wiley   +1 more source