Results 91 to 100 of about 1,797 (189)

Angustifonines A and B, Cytotoxic Bisindole Alkaloids from Bousigonia angustifolia

, 2016
Two new bisindole alkaloids, angustifonines A (1) and B (2), comprising the union of a rearranged monoterpenoid quinoline and an aspidospermine alkaloid, as well as 27 known indole alkaloids were isolated from the twigs and leaves of Bousigonia ...
Yu Zhang (12946), Shun-lin Li (1854142), Xiao-jiang Hao (1854148), Yan-hui Fu (1854145), Ying-tong Di (1854151), Hong-ping He (1854139)   +5 more
core   +1 more source

Macroline–sarpagine and macroline–pleiocarpamine bisindole alkaloids from Alstonia angustifolia

, 2012
Nine bisindole alkaloids, comprising four belonging to the macroline–sarpagine group, and five belonging to the macroline–pleiocarpamine group, were isolated from the stem-bark extracts of Alstonia angustifolia(Apocynacea).
Lim, K.H., Kam, T.S., Tan, S.J., Subramaniam, G.   +3 more
core   +1 more source

Bis-Indole Derivatives as Dual Nuclear Receptor 4A1 (NR4A1) and NR4A2 Ligands

Biomolecules
Bis-indole derived compounds such as 1,1-bis(3′-indolyl)-1-(3,5-disubstitutedphenyl) methane (DIM-3,5) and the corresponding 4-hydroxyl analogs (DIM8-3,5) are NR4A1 ligands that act as inverse NR4A1 agonists and are potent inhibitors of tumor growth. The
Srijana Upadhyay, Amanuel Esayas Hailemariam, Fuada Mariyam, Zahin Hafiz, Gregory Martin, Jainish Kothari, Evan Farkas, Gargi Sivaram, Logan Bell, Ronald Tjalkens, Stephen Safe   +10 more
doaj   +1 more source

Structure of methyltransferase RedM that forms the dimethylpyrrolinium of the bisindole reductasporine

Journal of Biological Chemistry
Bisindoles are biologically active natural products that arise from the oxidative dimerization of two molecules of l-tryptophan. In bacterial bisindole pathways, a core set of transformations is followed by the action of diverse tailoring enzymes that catalyze reactions that lead to diverse bisindole products.
Phillip Daniel-Ivad, Katherine S. Ryan
openaire   +2 more sources

Bisleucocurine A, a novel bisindole alkaloid from Leuconotis griffithii

, 2010
A novel bisindole alkaloid, bisleucocurine A (1), consisting of two strychnan skeletons with an N-1-C-17' and a C-12-C-2' bridges, was isolated from the leaves of Leuconotis griffithii and the structure was elucidated on the basis of spectroscopic data ...
Hirasawa, Y., Morita, H., Awang, K., Nugroho, A.E., Hosoya, T., Hadi, A.H.A.   +5 more
core   +1 more source

Huncaniterine A, a New Bisindole Alkaloid from Hunteria zeylanica

, 2007
A new bisindole alkaloid, huncaniterine A (1) consisting of corynantheine-type and aspidospermane-type skeletons, has been isolated from the bark of Hunteria zeylanica (Apocynaceae) and the structure was elucidated on the basis of spectroscopic data ...
Hirasawa, Yusuke, Mukhtar, Mat Ropi, Baba, Yuki, A. Hadi, A. Hamid, Zaima, Kazumasa, Matsuno, Yosuke, Morita, Hiroshi, Mohamad, Khalit, Awang, Khalijah, Suzuki, Tomoko   +9 more
core  

First Total Synthesis of the Kikai Island Polybrominated C3′–N1 Bisindole Alkaloid by a Directed Metalation Strategy

The first total synthesis of one out of four Kikai Island polybrominated C3′–N1 bisindole alkaloids from red alga Laurencia brongniartii is described.
Abe, Takumi, Tokushige, Keisuke
core   +1 more source

Directed Heterodimerization: Total Synthesis of (-)-Folicangine, (-)-Voafolidine, (-)-Isovoafolidine, and (-)-Tabernaesine B. [PDF]

Org Lett
Raclea RC, Movassaghi M.
europepmc   +1 more source

Correction: Discovery of potent bisindole-based pyrazolopyridine derivatives as topoisomerase inhibitors: DNA damage induction and synergistic antileukemic activity. [PDF]

Front Pharmacol
Eldehna WM, Tawfik HO, Veselá D, Peřina M, Negmeldin AT, Elsayed ZM, Majrashi TA, Vojáčková V, Elbadawi MM, Shaldam MA, Kryštof V, Abdel-Aziz HA.   +11 more
europepmc   +1 more source

K⁺/Cu²⁺ Co-chelated diastereoselective Friedel-Crafts reaction with chiral <i>N</i>-sulfinyl ketimines for the facile synthesis of chiral bisindoles and their cytotoxicity. [PDF]

RSC Adv
Yan S, Xu M, Liu Y, Du Z, Zhang G, Liu Z, Xiao J, Guo X, Liao G, Min Q, Xie B, Qin S.   +11 more
europepmc   +1 more source