Results 71 to 80 of about 1,592 (193)
Voacinol: a new bisindole alkaloid from Voacanga grandifolia (Miq) rolfe
, 1987 Voacinol, a new bisindole alkaloid from Voacanga grandifolia has been assigned a 14,14'-methylene-bis-18-hydroxytabersonine structure (1), on the basis of spectral ...
Govindachari, Tuticorin R. +3 more
core +1 more source
Cytotoxic Bisindole Alkaloids from a Marine Sponge Spongosorites sp.
, 2016 Three new bisindole alkaloids of the hamacanthin class (1−3) and one new bisindole alkaloid of the topsentin class (6) were isolated along with known bisindole alkaloids (4, 5, 7−11) from the MeOH extract of a marine sponge Spongosorites sp.
Qishi Sun (2681866) +7 more
core +1 more source
Molecules, 2019 Bisindolyl alkaloids represent a large family of natural and synthetic products that display various biological activities. Among the bisindole compounds, 6,7,12,13-tetrahydro-5H-cyclohepta[2,1-b:3,4-b’]diindoles have received little attention ...
Lei Peng, Xiaofei Zhang, Chunhao Yang
doaj +1 more source
From data to discovery: leveraging big data in plant natural products biosynthesis research
The Plant Journal, Volume 122, Issue 6, June 2025.SUMMARY Plant natural products or specialized metabolites play a vital role in drug discovery and development, with many clinically important derivatives such as the anticancer drugs topotecan (derived from the natural alkaloid camptothecin) and etoposide (derived from the natural polyphenol podophyllotoxin).
Matthew McConnachie +4 more
wiley +1 more source
Leucoridines A-D, cytotoxic strychnos-strychnos bisindole alkaloids from leuconotis
, 2010 Four new bisindole alkaloids of the Strychnos-Strychnos type, leucoridines A-D (1-4), were isolated from the stembark extract of Leuconotis griffithii.
Komiyama, K. +4 more
core +1 more source
, 2019 Examination of the EtOH extract of the leaves of the Malayan Tabernaemontana corymbosa resulted in the isolation of four new (1-4) and two known bisindole alkaloids (5, 6) of the Aspidosperma-Aspidosperma type.
Sim, Dawn Su Yin +6 more
core +1 more source
Advanced Synthesis &Catalysis, Volume 367, Issue 6, March 18, 2025.Abstract The synthesis of architecturally complex polyheterocyclic structures embedding the indole ring represents a growing field of interest. Carbolines and their partially dehydro derivatives, pyrazinoindoles, indoloindoles, azepinoindoles and other medium‐sized derivatives are only some examples of indole‐containing polycyclic compounds featured by
Alessandro Palmieri, Marino Petrini
wiley +1 more source
Reconstruction of Cladoniamide Biosynthesis Reveals Nonenzymatic Routes to Bisindole Diversity
, 2016 Indolotryptolines are bisindole natural products isolated from microbial and eDNA sources. Here, we report the sequence of transformations that convert an indolocarbazole to the indolotryptoline cladoniamide through reconstruction of the four-enzyme ...
Raymond J. Andersen (155984) +4 more
core +1 more source
Assessment of Mechanisms Involved in Antinociception Produced by the Alkaloid Caulerpine
Molecules, 2014 In previous works we showed that oral administration of caulerpine, a bisindole alkaloid isolated from algae of the genus Caulerpa, produced antinociception when assessed in chemical and thermal models of nociception.
Luiz Henrique Agra Cavalcante-Silva +11 more
doaj +1 more source
CNS Neuroscience &Therapeutics, Volume 31, Issue 2, February 2025.Neuroinflammation and blood–brain barrier disruption play key roles in the progression of vascular dementia, and necroptosis is closely associated with vascular dementia. This review guides the prevention and treatment of vascular dementia by discussing the tumor necrosis factor‐α signaling pathway, destruction of endothelial cells, glial cells, and ...
Yuemin Qiu +10 more
wiley +1 more source