Results 101 to 110 of about 1,592 (193)
MoleculesSynthetic efforts toward complex natural product (NP) scaffolds are useful ones, particularly those aimed at expanding their bioactive chemical space.
Darren C. Holland +3 more
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First De Novo Synthesis of the Bisindole Alkaloid Vinblastine.
ChemInform, 2002 AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire +4 more sources
Macroline–sarpagine and macroline–pleiocarpamine bisindole alkaloids from Alstonia angustifolia
, 2012 Nine bisindole alkaloids, comprising four belonging to the macroline–sarpagine group, and five belonging to the macroline–pleiocarpamine group, were isolated from the stem-bark extracts of Alstonia angustifolia(Apocynacea).
Lim, K.H. +3 more
core
The Raputindoles: Novel Cyclopentyl Bisindole Alkaloids from Raputia simulans
, 2016 A novel class of bisindole alkaloids is established by the isolation and structural determination of raputindoles A−D (1−4) from the Amazonian plant Raputia simulans Kallunki (Rutaceae).
Alexios-Leandros Skaltsounis (127086) +4 more
core +1 more source
Chapter 3 Noniridoid Bisindole Alkaloids
, 1995 This chapter discusses that indole is a reactive nucleus prone to dimerization when it is isolated or a part of tryptamine or tryptophan, which themselves are reactive toward many functionalities. For these reasons, bisindoles, the majority of which are of iridoid origin, are frequently isolated in nature. Besides these “dimers,” there exists a growing
Sapi, J., Massiot, G.
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, 2019 Catharanthus roseus contains a variety of monoterpenoid indole alkaloids (MIAs), among which bisindole alkaloids vinblastine and vincristine are well-known to have antitumor effects and widely used in clinical treatment.
Hang Wang (137566) +9 more
core +1 more source
Bis-Indole Derivatives as Dual Nuclear Receptor 4A1 (NR4A1) and NR4A2 Ligands
BiomoleculesBis-indole derived compounds such as 1,1-bis(3′-indolyl)-1-(3,5-disubstitutedphenyl) methane (DIM-3,5) and the corresponding 4-hydroxyl analogs (DIM8-3,5) are NR4A1 ligands that act as inverse NR4A1 agonists and are potent inhibitors of tumor growth. The
Srijana Upadhyay +10 more
doaj +1 more source
The first total synthesis of one out of four Kikai Island polybrominated C3′–N1 bisindole alkaloids from red alga Laurencia brongniartii is described.
Abe, Takumi, Tokushige, Keisuke
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Macroline–Sarpagine Bisindole Alkaloids with Antiproliferative Activity from Alstonia penangiana
, 2019 A methanol extract of the stem bark of the Malayan Alstonia penangiana provided seven new bisindole alkaloids, comprising six macroline–sarpagine alkaloids (angustilongines E–K, 1–6) and one macroline–pleiocarpamine bisindole alkaloid (angustilongine L ...
Yun-Yee Low +13 more
core +1 more source
, 2019 Catharanthus roseus contains a variety of monoterpenoid indole alkaloids (MIAs), among which bisindole alkaloids vinblastine and vincristine are well-known to have antitumor effects and widely used in clinical treatment.
Hang Wang (137566) +9 more
core +1 more source