Results 131 to 140 of about 1,055 (166)

Leucophyllinines A and B, bisindole alkaloids from Leuconotis eugeniifolia

Journal of Natural Medicines, 2019
Two new bisindole alkaloids, leucophyllinines A (1) and B (2) consisting of eburnane and quebrachamine-type skeletons were isolated from the bark of Leuconotis eugeniifolia, and their structures were elucidated on the basis of spectroscopic data. Leucophyllinines A and B showed antiplasmodial activities against Plasmodium falciparum 3D7.
Toshihiro Horii, Takahiro Tougan
exaly   +4 more sources

Alternative partial synthesis of bisindole alkaloids

Tetrahedron Letters, 1990
Abstract Indoline derivatives of the pericyclivine series are oxidized at position 6 with DDQ; the corresponding alcohols are coupled with nucleophilic indolines under acid conditions to yield dimers similar to undulatine.
G. Massiot, J.M. Nuzillard, B. Richard, L. Le Men-Olivier   +3 more
openaire   +1 more source

Development of novel telomerase inhibitors based on a Bisindole unit

Bioorganic & Medicinal Chemistry Letters, 2001
Telomerase is the enzyme that elongates telomere repeat at the ends of a chromosome. As high telomerase activity is observed in most cancer cells, inhibitors of human telomerase have been expected as new chemotherapeutic agents for cancer. We describe here the discovery of novel inhibitors with IC50 values in the submicromolar range.
S, Sasaki, T, Ehara, I, Sakata, Y, Fujino, N, Harada, J, Kimura, H, Nakamura, M, Maeda   +7 more
openaire   +2 more sources

Bisindoles

Chemistry of Heterocyclic Compounds, 1979
Sh. A. Samsoniya, M. V. Trapaidze, L. N. Kurkovskaya, L. G. Tret'yakova, T. K. Efimova, N. N. Suvorov   +5 more
openaire   +1 more source

Chapter 4 Bisindole Alkaloids

2006
Publisher Summary This chapter provides an overview on bisindole alkaloids. The indole–indole and tryptamine–tryptamine type, and related alkaloids are discussed. Tryptamine–tryptamine type with an additional monoterpene unit and related alkaloids are briefly discussed.
openaire   +1 more source

Bisindole

2020
Michio Sato, Shinji Kishimoto, Hiroshi Noguchi, Kenji Watanabe   +3 more
openaire   +1 more source

The bisindole alkaloid catharine

Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry, 1976
J. Guilhem, A. Ducruix, C. Riche, C. Pascard   +3 more
openaire   +1 more source

Synthetic strategies for the construction of C3–N1′ bisindoles

Organic & Biomolecular Chemistry
Natural products having a C3–N1′ bisindole framework are unique structures with potential axial chirality. This minireview summarizes the recent progress of the methodology for constructing C3–N1′ bisindoles along with the possible mechanism.
openaire   +3 more sources

Bisindole alkaloids

1971
J. E. Saxton, A. A. Gorman, M. Hesse, H. Schmid, P. G. Waser, W. H. Hopff   +5 more
openaire   +1 more source

Synthesis of a bisindole enyne with anticancer properties

Journal of the Indian Chemical Society, 2023
Ganesh Chandra Midya, Samir Mandal, Rakesh Paul, Jyotirmayee Dash   +3 more
openaire   +1 more source