Results 151 to 160 of about 1,797 (189)

Bisindole alkaloids.

The Alkaloids. Chemistry and biology, 2007
This chapter provides an overview on bisindole alkaloids. The indole–indole and tryptamine–tryptamine type, and related alkaloids are discussed. Tryptamine–tryptamine type with an additional monoterpene unit and related alkaloids are briefly discussed.
Kam, Toh Seok, Choo, Yeun Mun
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Synthesis of Marine Sponge Bisindole Alkaloids Dihydrohamacanthins

Organic Letters, 2002
[structure: see text] A convergent synthesis of the marine sponge bisindole alkaloids dihydrohamacanthins is described. The synthesis centers on the construction of 3,5- and 3,6-linked pyrazinones and their reduction to the requisite piperazinones with sodium cyanoborohydride.
Fumiko Y, Miyake, Kenichi, Yakushijin, David A, Horne   +2 more
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ChemInform Abstract: Bisindole Alkaloids

ChemInform, 2009
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Toh‐Seok Kam, Yeun‐Mun Choo
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Synthesis of a novel series of cytotoxic bisindole alkaloids

Bioorganic & Medicinal Chemistry Letters, 2001
Original cytotoxic bisindole alkaloids with a 1,2,3,4-tetrahydroquinoline bridge were synthesized by reductive amination with various anilines. The most cytotoxic compounds display a high and dose-dependent cell cycle effect with accumulation in the G1 phase.
M, Raoul, C, Schaeffer, S, Léonce, A, Pierré, G, Atassi, R, Hocquemiller, G, Lewin   +6 more
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Bisindoles. 30. Acid condensation of bisindoles with aromatic aldehydes and the synthesis of new endole-containing polyamines

Chemistry of Heterocyclic Compounds, 1993
Reaction of 2,2′-diethoxycarbonyl-bis(5-indolyl)sulfone with benzaldehyde gave an active dibromide — 2,2′diethoxycarbonyl-3,3′-di(bromobenzyl)bis(5-indolyl)sulfone; derivatives of di(bisindolyl)phenylmethane have been prepared by condensation of 2,2′-diethoxycarbonyl-bis (N-methyl-5-indolyl)sulfone with benzaldehyde and p-methoxybenzaldhyde.
N. N. Ovsyannikova, Sh. A. Samsoniya, N. N. Suvorov, N. A. Kogan   +3 more
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Development of novel telomerase inhibitors based on a Bisindole unit

Bioorganic & Medicinal Chemistry Letters, 2001
Telomerase is the enzyme that elongates telomere repeat at the ends of a chromosome. As high telomerase activity is observed in most cancer cells, inhibitors of human telomerase have been expected as new chemotherapeutic agents for cancer. We describe here the discovery of novel inhibitors with IC50 values in the submicromolar range.
S, Sasaki, T, Ehara, I, Sakata, Y, Fujino, N, Harada, J, Kimura, H, Nakamura, M, Maeda   +7 more
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Alternative partial synthesis of bisindole alkaloids

Tetrahedron Letters, 1990
Abstract Indoline derivatives of the pericyclivine series are oxidized at position 6 with DDQ; the corresponding alcohols are coupled with nucleophilic indolines under acid conditions to yield dimers similar to undulatine.
G. Massiot, J.M. Nuzillard, B. Richard, L. Le Men-Olivier   +3 more
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Bisindoles

Chemistry of Heterocyclic Compounds, 1979
Sh. A. Samsoniya, M. V. Trapaidze, L. N. Kurkovskaya, L. G. Tret'yakova, T. K. Efimova, N. N. Suvorov   +5 more
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Bisindole

2020
Michio Sato, Shinji Kishimoto, Hiroshi Noguchi, Kenji Watanabe   +3 more
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The bisindole alkaloid catharine

Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry, 1976
J. Guilhem, A. Ducruix, C. Riche, C. Pascard   +3 more
openaire   +1 more source