Results 141 to 150 of about 1,797 (189)
Genomic and phenotypic characterization of indigenous violacein-producing Chromobacterium amazonense SAM215 from lake sediment in Bangladesh. [PDF]
Sci RepTarafdar MR +10 more
europepmc +1 more source
Parallel evolution of methyltransferases leads to vobasine biosynthesis in Tabernaemontana elegans and Catharanthus roseus. [PDF]
Front Plant SciFarzana M +6 more
europepmc +1 more source
Leucophyllinines A and B, bisindole alkaloids from Leuconotis eugeniifolia
Journal of Natural Medicines, 2019 Two new bisindole alkaloids, leucophyllinines A (1) and B (2) consisting of eburnane and quebrachamine-type skeletons were isolated from the bark of Leuconotis eugeniifolia, and their structures were elucidated on the basis of spectroscopic data. Leucophyllinines A and B showed antiplasmodial activities against Plasmodium falciparum 3D7.
Toshihiro Horii, Takahiro Tougan
exaly +5 more sources
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Archiv Der Pharmazie, 2020
AbstractThe bisindole moiety, as a versatile pharmacophore, is one of the widespread heterocycles in naturally occurring and synthetic bioactive compounds. The bisindole alkaloids derived from natural sources possess structural and mechanistic diversity, and they were found to be generally more active than monoindole alkaloids against various cancer ...
Yue Zhang, Chunhong Hu
exaly +3 more sources
AbstractThe bisindole moiety, as a versatile pharmacophore, is one of the widespread heterocycles in naturally occurring and synthetic bioactive compounds. The bisindole alkaloids derived from natural sources possess structural and mechanistic diversity, and they were found to be generally more active than monoindole alkaloids against various cancer ...
Yue Zhang, Chunhong Hu
exaly +3 more sources
Monoterpenoid Bisindole Alkaloids
The Alkaloids Chemistry and Biology, 2016This chapter covers the literature on bisindole alkaloids consisting of monoterpenoid indoles, published up to June 2015. Bisindole alkaloids isolated from plants belonging to the families Apocynaceae and Loganiaceae, including Iboga-vobasine type, Aspidosperma-Aspidosperma type, eburnan-Aspidosperma type, Strychnos-Strychnos type, macroline-macroline ...
Mariko Kitajima
exaly +3 more sources
Structure of a novel bisindole derivative
Acta Crystallographica Section C Crystal Structure Communications, 1991(3aR-[3a alpha,4 beta,5a beta,9[1R,3R(2S),5R,7aS,-12aS],10bR,13a alpha])-Methyl-4-(acetyloxy)-3a-ethyl-3a,4,5,5a,6,11,12,13a-oct ahy dro-9- [1,2,3,4,6,7,7a,- 12-octahydro-3-(2-hydroxy-2-hydroxymethylbutyl)- 1-(methoxycarbonyl)indolizino[1,2-b]indol-7a-yl]-5- hydroxy-8-methoxy-6-methyl-1H-indolizino[8,1-c,d]- carbazole-5-carboxylate methanol hydrate ...
V M, Lynch +3 more
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Catalytic repertoire of bacterial bisindole formation
Current Opinion in Chemical Biology, 2016Bacterial bisindole alkaloids that derive from the oxidative dimerization of l-tryptophan possess diversified biological activities and unique molecular structures. In recent years, the number of bisindoles and their gene clusters has greatly expanded, revealing a large genetic toolbox for the generation of unique structural modifications.
Yi-Ling, Du, Katherine S, Ryan
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Enantioselective Synthesis of N−N Bisindole Atropisomers
Angewandte Chemie, 2022AbstractN−N Atropisomers are a common motif in natural products and represent a significant dimension for exploration in modern pharmaceutical and medicinal chemistry. However, the catalytic atroposelective synthesis of such molecules remains challenging, hampering meaningful development.
Peng Zhang +6 more
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Bisindole alkaloids from Tabernaemontana corymbosa
Phytochemistry, 2018Continued study in bioactive monoterpenoid alkaloids led to the isolation of nine undescribed alkaloids, taberyunines A-I, together with 32 known ones from the aerial parts of Tabernaemontana corymbosa Roxb. ex Wall (Apocynaceae). Among the undescribed alkaloids, taberyunines A-G and H-I were assigned to Aspidosperma-Aspidosperma and Vobasinyl-Ibogan ...
Bing-Jie, Zhang +6 more
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New Synthetic Protocol for the Preparation of Unsymmetrical Bisindoles.
ChemInform, 2006AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Hanns Martin, Kaiser +5 more
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