Results 141 to 150 of about 2,045 (191)
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Design and Synthesis of Novel β‐Carboline‐Bisindole Hybrids as Potential Anticancer Agents
ChemMedChemWe are reporting a short and convenient pathway for the synthesis of novel β‐carboline‐bisindole hybrid compounds from relatively cheap and commercially available chemicals such as tryptamine, dialdehydes and indoles.
Nguyen Thi Thanh Huyen +9 more
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Insecticidal bisindole alkaloids from leaves of Tabernaemontana divaricata 'Dwaft'.
PhytochemistrySix undescribed bisindole alkaloids, namely taberdisines A-F (1-6), were isolated from the leaves of Tabernaemontana divaricata 'Dwaft'. Among them, alkaloids 1 and 2 were the first examples of strychnos-iboga type alkaloid with both C-C linkage patterns.
Jing Chen +2 more
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Phytochemistry, 2021
The Melodinus species have been proved to be good resources of bisindole alkaloids. Six bisindole alkaloids were isolated from the leaves and stems of Melodinus cochinchinensis (Lour.) Merr. guided by HRESIMS data analysis.
Fang-Ru Li +8 more
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The Melodinus species have been proved to be good resources of bisindole alkaloids. Six bisindole alkaloids were isolated from the leaves and stems of Melodinus cochinchinensis (Lour.) Merr. guided by HRESIMS data analysis.
Fang-Ru Li +8 more
semanticscholar +1 more source
The Alkaloids. Chemistry and biology, 2007
This chapter provides an overview on bisindole alkaloids. The indole–indole and tryptamine–tryptamine type, and related alkaloids are discussed. Tryptamine–tryptamine type with an additional monoterpene unit and related alkaloids are briefly discussed.
Kam, Toh Seok, Choo, Yeun Mun
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This chapter provides an overview on bisindole alkaloids. The indole–indole and tryptamine–tryptamine type, and related alkaloids are discussed. Tryptamine–tryptamine type with an additional monoterpene unit and related alkaloids are briefly discussed.
Kam, Toh Seok, Choo, Yeun Mun
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ACS Infectious Diseases
About 100,000 deaths are attributed annually to infections with methicillin-resistant Staphylococcus aureus (MRSA) despite concerted efforts toward vaccine development and clinical trials involving several preclinically efficacious drug candidates.
E. T. Adeniyi +9 more
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About 100,000 deaths are attributed annually to infections with methicillin-resistant Staphylococcus aureus (MRSA) despite concerted efforts toward vaccine development and clinical trials involving several preclinically efficacious drug candidates.
E. T. Adeniyi +9 more
semanticscholar +1 more source
European journal of medicinal chemistry, 2021
This study presents the design, synthesis, and characterization of bisindole molecules as anti-cancer agents against Tousled-like kinases (TLKs). We show that compound 2 composed of an indirubin-3'-oxime group linked with a (N-methylpiperidin-2-yl)ethyl ...
Sung-Bau Lee +5 more
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This study presents the design, synthesis, and characterization of bisindole molecules as anti-cancer agents against Tousled-like kinases (TLKs). We show that compound 2 composed of an indirubin-3'-oxime group linked with a (N-methylpiperidin-2-yl)ethyl ...
Sung-Bau Lee +5 more
semanticscholar +1 more source
Chemistry and Biodiversity
Bisindole alkaloids constitute a significant class of natural compounds distinguished by their characteristic bisindole structure and renowned for their anticancer properties. Over the last six decades, researchers have isolated 425 microorganism‐derived
Zi-long Zhang +7 more
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Bisindole alkaloids constitute a significant class of natural compounds distinguished by their characteristic bisindole structure and renowned for their anticancer properties. Over the last six decades, researchers have isolated 425 microorganism‐derived
Zi-long Zhang +7 more
semanticscholar +1 more source
Bisindole alkaloid artifacts from Gonioma malagasy
Tetrahedron Letters, 2013Abstract Three new bisindole alkaloids ( 1 – 3 ), possessing a rare carbon skeleton formed by two indole moieties fused via a dihydropyran unit, were isolated from the alkaloid extract of the stem bark of Gonioma malagasy . Their structure and absolute configuration were assigned thanks to a combination of one and two dimensional NMR spectroscopy ...
Beniddir, Mehdi A +5 more
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New Bisindole Alkaloids from Petchia Ceylanica
HETEROCYCLES, 1988Two new bisindole alkaloids, ceylanine and ceylanicine, habe been isolated from Petchia ceylanica and their structures have been established on the basis of spectroscopic ...
_ Atta-ur-Rahman +4 more
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Bioorganic chemistry (Print)
Eleven undescribed monoterpenoid bisindole alkaloids, alstomaphyines A-K (1-11), along with three known analogues were isolated from the leaves and stem bark of the Alstonia macrophylla.
Zi-wei Li +8 more
semanticscholar +1 more source
Eleven undescribed monoterpenoid bisindole alkaloids, alstomaphyines A-K (1-11), along with three known analogues were isolated from the leaves and stem bark of the Alstonia macrophylla.
Zi-wei Li +8 more
semanticscholar +1 more source