Results 141 to 150 of about 1,592 (193)

Rational design and synthesis of non-competitive transcription inhibitors targeting a conserved RNA polymerase-σ ^<i>A</i> interface. [PDF]

RSC Adv
Tandi M, Hati N, Kore M, Behera D, Patel T, Eeba, Agarwal N, Gopal B, Sundriyal S.   +8 more
europepmc   +1 more source

Total Synthesis of the Spirocyclic Bis-Indole Alkaloid (-)-Owerreine via a [4+2] Annulation. [PDF]

Angew Chem Int Ed Engl
Coll E, Gandon V, Kouklovsky C, Evanno L, Vincent G.   +4 more
europepmc   +1 more source

FeCl₃/SiO₂-catalyzed bis-indolylation of acetals and ketals: a highly atom-economical approach to the selective deprotection of protected carbohydrates. [PDF]

RSC Adv
Das B, Das K, De UC, Majumdar S.
europepmc   +1 more source

Conofolidine: A Natural Plant Alkaloid That Causes Apoptosis and Senescence in Cancer Cells. [PDF]

Molecules
Al-Hayali MZ, Nge CE, Lim KH, Collins HM, Kam TS, Bradshaw TD.   +5 more
europepmc   +1 more source

Globospiramine from Voacanga globosa Exerts Robust Cytotoxic and Antiproliferative Activities on Cancer Cells by Inducing Caspase-Dependent Apoptosis in A549 Cells and Inhibiting MAPK14 (p38α): In Vitro and Computational Investigations. [PDF]

Cells
Manzano JAH, Abellanosa EA, Aguilar JP, Brogi S, Yen CH, Macabeo APG, Austriaco N.   +6 more
europepmc   +1 more source

Discovery of Antimicrobial Oligoindoles from a Cold-Seep-Derived <i>Halomonas</i> Strain. [PDF]

Mar Drugs
Yan Y, Li Z, Li H, Sun J, Li W, Xiao F.
europepmc   +1 more source

The toxic components, toxicological mechanism and effective antidote for <i>Gelsemium elegans</i> poisoning. [PDF]

Acta Pharm Sin B
Li N, Yang Y, Zhang S, Jiang B, Zhang W, Wang H, Chen L, Wang L, Li Y, Shi L, Ye W, Wang L.   +11 more
europepmc   +1 more source

Leucophyllinines A and B, bisindole alkaloids from Leuconotis eugeniifolia

Journal of Natural Medicines, 2019
Two new bisindole alkaloids, leucophyllinines A (1) and B (2) consisting of eburnane and quebrachamine-type skeletons were isolated from the bark of Leuconotis eugeniifolia, and their structures were elucidated on the basis of spectroscopic data. Leucophyllinines A and B showed antiplasmodial activities against Plasmodium falciparum 3D7.
Alfarius Eko Nugroho, Yusuke Hirasawa, Takahiro Tougan   +2 more
exaly   +5 more sources

Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis

Phytochemistry, 2010
Leucofoline and leuconoline, representing the first members of the aspidospermatan–aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii.
Yun-Yee Low, Toh-Seok Kam
exaly   +3 more sources

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Anticancer activity of bisindole alkaloids derived from natural sources and synthetic bisindole hybrids

Archiv Der Pharmazie, 2020
AbstractThe bisindole moiety, as a versatile pharmacophore, is one of the widespread heterocycles in naturally occurring and synthetic bioactive compounds. The bisindole alkaloids derived from natural sources possess structural and mechanistic diversity, and they were found to be generally more active than monoindole alkaloids against various cancer ...
Yue Zhang, Chengping Hu
exaly   +3 more sources