Results 161 to 170 of about 2,460 (195)
Marine Streptomyces-Derived Novel Alkaloids Discovered in the Past Decade. [PDF]
Mar DrugsLiu Z, Sun W, Hu Z, Wang W, Zhang H.
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Biomimetic total synthesis of ten <i>Securinega</i> alkaloids.
Org Chem FrontWaddell LJN +4 more
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Archiv der Pharmazie, 2020
AbstractThe bisindole moiety, as a versatile pharmacophore, is one of the widespread heterocycles in naturally occurring and synthetic bioactive compounds. The bisindole alkaloids derived from natural sources possess structural and mechanistic diversity, and they were found to be generally more active than monoindole alkaloids against various cancer ...
Yue Zhang, Chunhong Hu
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AbstractThe bisindole moiety, as a versatile pharmacophore, is one of the widespread heterocycles in naturally occurring and synthetic bioactive compounds. The bisindole alkaloids derived from natural sources possess structural and mechanistic diversity, and they were found to be generally more active than monoindole alkaloids against various cancer ...
Yue Zhang, Chunhong Hu
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Enantioselective Synthesis of N−N Bisindole Atropisomers
Angewandte Chemie, 2022AbstractN−N Atropisomers are a common motif in natural products and represent a significant dimension for exploration in modern pharmaceutical and medicinal chemistry. However, the catalytic atroposelective synthesis of such molecules remains challenging, hampering meaningful development.
Peng Zhang +6 more
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Bisindole alkaloids from Tabernaemontana corymbosa
Phytochemistry, 2018Continued study in bioactive monoterpenoid alkaloids led to the isolation of nine undescribed alkaloids, taberyunines A-I, together with 32 known ones from the aerial parts of Tabernaemontana corymbosa Roxb. ex Wall (Apocynaceae). Among the undescribed alkaloids, taberyunines A-G and H-I were assigned to Aspidosperma-Aspidosperma and Vobasinyl-Ibogan ...
Bing-Jie, Zhang +6 more
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Monoterpenoid Bisindole Alkaloids
2016This chapter covers the literature on bisindole alkaloids consisting of monoterpenoid indoles, published up to June 2015. Bisindole alkaloids isolated from plants belonging to the families Apocynaceae and Loganiaceae, including Iboga-vobasine type, Aspidosperma-Aspidosperma type, eburnan-Aspidosperma type, Strychnos-Strychnos type, macroline-macroline ...
Mariko, Kitajima, Hiromitsu, Takayama
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Catalytic repertoire of bacterial bisindole formation
Current Opinion in Chemical Biology, 2016Bacterial bisindole alkaloids that derive from the oxidative dimerization of l-tryptophan possess diversified biological activities and unique molecular structures. In recent years, the number of bisindoles and their gene clusters has greatly expanded, revealing a large genetic toolbox for the generation of unique structural modifications.
Yi-Ling, Du, Katherine S, Ryan
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Structure of a novel bisindole derivative
Acta Crystallographica Section C Crystal Structure Communications, 1991(3aR-[3a alpha,4 beta,5a beta,9[1R,3R(2S),5R,7aS,-12aS],10bR,13a alpha])-Methyl-4-(acetyloxy)-3a-ethyl-3a,4,5,5a,6,11,12,13a-oct ahy dro-9- [1,2,3,4,6,7,7a,- 12-octahydro-3-(2-hydroxy-2-hydroxymethylbutyl)- 1-(methoxycarbonyl)indolizino[1,2-b]indol-7a-yl]-5- hydroxy-8-methoxy-6-methyl-1H-indolizino[8,1-c,d]- carbazole-5-carboxylate methanol hydrate ...
V M, Lynch +3 more
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ChemInform Abstract: Bisindole Alkaloids
ChemInform, 2009AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Toh‐Seok Kam, Yeun‐Mun Choo
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Synthesis of Marine Sponge Bisindole Alkaloids Dihydrohamacanthins
Organic Letters, 2002[structure: see text] A convergent synthesis of the marine sponge bisindole alkaloids dihydrohamacanthins is described. The synthesis centers on the construction of 3,5- and 3,6-linked pyrazinones and their reduction to the requisite piperazinones with sodium cyanoborohydride.
Fumiko Y, Miyake +2 more
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