Results 11 to 20 of about 115,328 (341)
Journal of Orthopaedic Translation, 2020 Objective: The objective of this study was to assess the efficacy and safety of denosumab therapy in osteoporotic postmenopausal women who were previously treated with bisphosphonates. Methods: Meta-analyses of four available randomised controlled trials
Yilin Zhu +9 more
doaj +1 more source
Therapeutic Advances in Chronic Disease, 2022 Background: Bisphosphonates are a type of medication that prevents the loss of bone density. Secondary childhood osteoporosis reduces bone strength and results in an increased risk of fragility fracture.
Huawei Zhao +5 more
doaj +1 more source
Atypical femur fractures associated with chronic bisphosphonates use: A case series with 66 patients [PDF]
Revista Brasileira de Ortopedia, 2022 Objective The present study aims to describe outcomes from a series of surgically treated patients with atypical femoral fracture due to bisphosphonates use, in addition to correlate the time of previous medication use with fracture consolidation time ...
Guilherme Guadagnini Falotico +5 more
doaj +1 more source
Enhanced osteogenic differentiation in zoledronate-treated osteoporotic patients [PDF]
, 2017 Bisphosphonates are well known inhibitors of osteoclast activity and thus may be employed to influence osteoblast activity. The present study was designed to evaluate the in vivo effects of zoledronic acid (ZA) on the proliferation and osteoblastic ...
Carbonare, Luca Dalle +7 more
core +6 more sources
eJournal of Oral Maxillofacial Research, 2023 Objectives: The aim of this cross-sectional study is to evaluate Lithuanian fourth- and fifth-year dental students' knowledge about bisphosphonates and bisphosphonate-related osteonecrosis of the jaw. Material and Methods: The anonymous survey using a
Greta Sereikaite +4 more
doaj +1 more source
Journal of Bone and Mineral Research, 2020 Bisphosphonates are the first‐line treatment for preventing fractures in osteoporosis patients. However, their use is contraindicated or to be used with caution in chronic kidney disease (CKD) patients, primarily because of a lack of information about ...
D. Robinson +19 more
semanticscholar +1 more source
Incidence and Risk Factors of Bisphosphonate-Related Osteonecrosis of the Jaw in Multiple Myeloma Patients Having Undergone Autologous Stem Cell Transplantation [PDF]
, 2012 Background: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe complication of bisphosphonate therapy. Due to their long survival and subsequently high cumulative doses of bisphosphonates, multiple myeloma patients have the highest risk ...
Baumann, Philipp +9 more
core +1 more source
Decreased risk of breast cancer associated with oral bisphosphonate therapy [PDF]
, 2012 Preclinical studies and adjuvant trials using bisphosphonates have found them to have an antitumor effect. Although major advances have been made in chemoprevention strategies with selective estrogen receptor modulators and aromatase inhibitors, their ...
Brufsky, A, Mathew, A
core +2 more sources
Pain outcomes in patients with bone metastases from advanced cancer: assessment and management with bone-targeting agents [PDF]
, 2014 Bone metastases in advanced cancer frequently cause painful complications that impair patient physical activity and negatively affect quality of life. Pain is often underreported and poorly managed in these patients.
A Kretzschmar +69 more
core +1 more source
Bisphosphonates Target B Cells to Enhance Humoral Immune Responses
Cell Reports, 2013 Bisphosphonates are a class of drugs that are widely used to inhibit loss of bone mass in patients. We show here that the administration of clinically relevant doses of bisphosphonates in mice increases antibody responses to live and inactive viruses ...
Elena Tonti +14 more
doaj +1 more source