Tiludronate and clodronate do not affect bone structure or remodeling kinetics over a 60 day randomized trial [PDF]
, 2018 Background Tiludronate and clodronate are FDA-approved bisphosphonate drug therapies for navicular disease in horses. Although clinical studies have determined their ability to reduce lameness associated with skeletal disorders in horses, data regarding
Gillett, Ashley N. +3 more
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Long Term Bisphosphonate Use in Osteoporotic Patients; A Step Forward, Two Steps Back
Journal of Pharmacy & Pharmaceutical Sciences, 2012 Purpose. Bisphosphonates are the main class of drugs widely used in prevention and treatment of osteoporosis. Along with the beneficial effects, recent studies point to the harms of long-term treatment with bisphosphonates. Methods.
Pooneh Salari, Mohammad Abdollahi
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Effect of bisphosphonates on bone giant cell tumor recurrence: a meta-analysis
Beni-Suef University Journal of Basic and Applied Sciences, 2022 Background We examined the impact of bisphosphonates as adjuvant therapy on the recurrence of giant cell bone tumors and the impact of various tumor stages and surgical techniques on this effect.
Marwa Mohsen +4 more
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Therapeutic Advances in Medical Oncology, 2019 Background: Adjuvant bisphosphonates reduce the rate of breast cancer recurrence in the bone and improve breast cancer survival. However, the risk of adverse events associated with bisphosphonate therapy for breast cancer remains poorly defined. Methods:
Yan-Li Yang +4 more
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Oral Mucosal Ulcer Associated with Improper Usage of Bisphosphonate: A Case Report
Türk Osteoporoz Dergisi, 2023 Bisphosphonates are widely used agents for osteoporosis. Although bisphosphonates are generally well-tolerated drugs, especially oral forms may have gastrointestinal system side effects.
Şeyma Nur Bayındır +2 more
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Dynamics of Bone Trap-5b Level in Patients with Bone Metastases of Renal Cell Cancer at Combined Treatment [PDF]
, 2017 The objective of this study was to determine the sensitivity of tartrate-resistant acid phosphatase (Bone TRAP-5b) for early detection of bone metastases (BM) and to investigate the efficacy of bisphosphonates (BF) (zolendronic acid-ZA) in prevention of ...
Boichuk, S. (Serhiy) +3 more
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Osteonecrose da mandíbula associada a bifosfonatos intravenosos em doentes oncológicos.
Acta Médica Portuguesa, 2008 Bisphosphonates are synthetic analogs of inorganic pyrophosphate, which are not only potent inhibitors of osteoclast-mediated bone resorption, but also present an important inhibitory activity of angiogenesis.
Ana Carvalho +3 more
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Use of bisphosphonates in bone pathology – benefits and risks [PDF]
Romanian Journal of Rheumatology, 2023 This article aims to establish, on the basis of medical literature and of the authors’ experience, whether bisphosphonates still have a role in treating skeletal diseases, with increased bone resorption. The effects of bisphosphonates on the bone tissue,
Dinu Antonescu, Cristian Ioan Stoica
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Effects of the anti-RANKL antibody denosumab on joint structural damage in patients with rheumatoid arthritis treated with conventional synthetic disease-modifying antirheumatic drugs (DESIRABLE study): a randomised, double-blind, placebo-controlled phase 3 trial. [PDF]
, 2019 ObjectiveTo evaluate the efficacy of denosumab in suppressing joint destruction when added to conventional synthetic disease-modifying antirheumatic drug (csDMARD) therapy in patients with rheumatoid arthritis (RA).MethodsThis was a multi-centre ...
Genant, Harry K +9 more
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BISPHOSPHONATE INDUCED OSTEONECROSIS OF THE JAWS AND CURRENT THERAPIES
Cumhuriyet Dental Journal, 2017 Bisphosphonates are pharmacological agents which are the potent inhibitors of osteoclastic activity. Nowadays, bisphosphonates are used to treat a variety of bone disease or related complications such as metastatic or osteolytic bone disease ...
Damla Torul, Mehmet Cihan Bereket
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