Results 1 to 10 of about 2,567 (114)

Exploring the mechanism of BK polyomavirus-associated nephropathy through consensus gene network approach. [PDF]

PLoS ONE, 2023
BK polyomavirus-associated nephropathy occurs in kidney transplant recipients under immunosuppressive treatment. BK polyomavirus is implicated in cancer development and invasion, and case reports of renal cell carcinoma and urothelial carcinoma possibly ...
Noriaki Sato, Keita P Mori, Kaoru Sakai, Hitomi Miyata, Shinya Yamamoto, Takashi Kobayashi, Hironori Haga, Motoko Yanagita, Yasushi Okuno   +8 more
doaj   +4 more sources

Clinical and immunological characteristics for BK polyomavirus‐associated nephropathy after kidney transplantation [PDF]

Immunity, Inflammation and Disease, 2023
Introduction BK polyomavirus (BKPyV)‐associated nephropathy (BKPyVAN) can cause a significant risk of allograft impairment after kidney transplantation (KT). Intact BKPyV‐specific immunity is associated with viral containment.
Tanaya Siripoon, Nopporn Apiwattanakul, Pannawat Mongkolrattanakul, Chutatip Tongsook, Nattawut Unwanatham, Suradej Hongeng, Surasak Kantachuvesiri, Jackrapong Bruminhent   +7 more
doaj   +5 more sources

High Incidence and Early Onset of Urinary Tract Cancers in Patients with BK Polyomavirus Associated Nephropathy [PDF]

Viruses, 2021
Over-immunosuppressed kidney transplant recipients are susceptible to malignancies and BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN). This study aimed to verify the association between BKPyV infection and urinary tract cancers (UTC).
Yi-Jung Li, Hsin-Hsu Wu, Cheng-Hsu Chen, Hsu-Han Wang, Yang-Jen Chiang, Hsiang-Hao Hsu, See-Tong Pang, Robert Y. L. Wang, Ya-Chung Tian   +8 more
doaj   +5 more sources

Endoplasmic Reticulum Stress Mediates Renal Tubular Vacuolation in BK Polyomavirus-Associated Nephropathy [PDF]

Frontiers in Endocrinology, 2022
ObjectiveThis study aimed to explore the molecular mechanism of cytoplasmic vacuolation caused by BK polyomavirus (BKPyV) and thus search for potential target for drug repurposing.MethodsMorphological features of BK polyomavirus-associated nephropathy ...
Guo-Dong Zhao, Rong Gao, Xiao-Tao Hou, Hui Zhang, Xu-Tao Chen, Jin-Quan Luo, Hui-Fei Yang, Tong Chen, Xue Shen, Shi-Cong Yang, Cheng-Lin Wu, Gang Huang   +11 more
doaj   +4 more sources

Development of BK polyomavirus-associated nephropathy risk prediction in kidney transplant recipients [PDF]

Renal Failure
Background With the development of potential prevention therapies for BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN), risk prediction models are needed to identify kidney transplant recipients at high risk for BKPyVAN.Methods This single-center
Junji Yamauchi, Katalin Fornadi, Divya Raghavan, Duha Jweehan, Suayp Oygen, Silviana Marineci, Michelle Buff, Michael Fenlon, Motaz Selim, Michael Zimmerman, Miklos Z. Molnar   +10 more
doaj   +3 more sources

BK Polyomavirus-specific T cell immune responses in kidney transplant recipients diagnosed with BK Polyomavirus-associated nephropathy [PDF]

BMC Infectious Diseases, 2019
Background Adjustment of immunosuppression is the main therapy for BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN) after kidney transplantation (KT). Studies of BKPyV-specific T cell immune response are scarce.
Jackrapong Bruminhent, Supranart Srisala, Chompunut Klinmalai, Subencha Pinsai, Siriorn P. Watcharananan, Surasak Kantachuvesiri, Suradej Hongeng, Nopporn Apiwattanakul   +7 more
doaj   +5 more sources

Clinical Efficacy of Intravenous Immunoglobulin for BK Polyomavirus-Associated Nephropathy After Living Kidney Transplantation [PDF]

Therapeutics and Clinical Risk Management, 2020
Soichi Matsumura,1 Taigo Kato,1,2 Ayumu Taniguchi,1 Masataka Kawamura,1 Shigeaki Nakazawa,1 Tomoko Namba-Hamano,3 Toyofumi Abe,1 Norio Nonomura,1 Ryoichi Imamura1 1Department of Urology, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan;
Matsumura S, Kato T, Taniguchi A, Kawamura M, Nakazawa S, Namba-Hamano T, Abe T, Nonomura N, Imamura R   +8 more
doaj   +4 more sources

Urine Donor–Derived Cell-Free DNA Helps Discriminate BK Polyomavirus-Associated Nephropathy in Kidney Transplant Recipients With BK Polyomavirus Infection [PDF]

Frontiers in Immunology, 2020
Background: Studies have shown that plasma donor–derived cell-free DNA (dd-cfDNA) can predict renal allograft antibody-mediated rejection. This study was performed to evaluate the value of urine dd-cfDNA concentration and dd-cfDNA fraction (%) for ...
Xu-Tao Chen, Xu-Tao Chen, Xu-Tao Chen, Wen-Fang Chen, Jun Li, Jun Li, Jun Li, Rong-Hai Deng, Rong-Hai Deng, Rong-Hai Deng, Yang Huang, Yang Huang, Yang Huang, Shi-Cong Yang, Pei-Song Chen, Ting-Ya Jiang, Hai-Tao Liu, Chang-Xi Wang, Chang-Xi Wang, Chang-Xi Wang, Li-Zhong Chen, Li-Zhong Chen, Li-Zhong Chen, Jiang Qiu, Jiang Qiu, Jiang Qiu, Gang Huang, Gang Huang, Gang Huang   +28 more
doaj   +5 more sources

BK polyomavirus-associated nephropathy [PDF]

Childhood Kidney Diseases, 2022
BK polyomavirus (BKPyV) is a ubiquitous virus residing in the kidney tubules and is clinically significant only in immunocompromised patients. In clinical practice, BKPyV is a causative pathogen of BKPyV-associated nephropathy (BKVAN) in kidney allograft
Yo Han Ahn, Hee Gyung Kang
doaj   +2 more sources

A delicate balance between rejection and BK polyomavirus associated nephropathy; A retrospective cohort study in renal transplant recipients. [PDF]

PLoS ONE, 2017
BackgroundThe immunosuppressive agents mycophenolate acid (MPA) and tacrolimus (Tac) are associated with a higher incidence of BK polyomavirus nephropathy (BKPyVAN).
Lilli Gard, Willem van Doesum, Hubert G M Niesters, Willem J van Son, Arjan Diepstra, Coen A Stegeman, Henk Groen, Annelies Riezebos-Brilman, Jan Stephan Sanders   +8 more
doaj   +5 more sources