Results 21 to 30 of about 2,606 (151)

Innate Immunity Response to BK Virus Infection in Polyomavirus-Associated Nephropathy in Kidney Transplant Recipients [PDF]

Transplantology, 2022
BK polyomavirus (BKV) mainly causes infection in uroepithelial and renal tubular epithelial cells of either immunocompetent or immunocompromised hosts.
Wiwat Chancharoenthana, Asada Leelahavanichkul   +1 more
doaj   +2 more sources

BK Polyomavirus in Renal Transplantation: Virological Notes for Monitoring and Diagnosis [PDF]

Biomolecules
Polyomavirus-associated nephropathy was first reported over 50 years ago. However, it still represents a cause of renal injury in kidney transplant recipients, particularly in the first two years post-transplantation, with occurrence rates of 1–10%.
Cristina Costa, Francesca Sidoti, Alessandro Bondi, Antonio Curtoni   +3 more
doaj   +2 more sources

Cell-Free Mitochondrial DNA: An Upcoming Non-Invasive Tool for Diagnosis of BK Polyomavirus-Associated Nephropathy. [PDF]

Biomolecules
Mitochondria are essential organelles that possess their own DNA. Mitochondrial dysfunction has been revealed in many kidney diseases, including BK polyomavirus-associated nephropathy (BKPyVAN). In this study, we introduce an innovative approach for non-invasive monitoring of mitochondrial impairment through urinary donor-derived cell-free ...
Guo L, Luo S, Wang X, Zhang N, Cheng Y, Shen J, Chen J, Wang R.   +7 more
europepmc   +4 more sources

BK and JC polyomavirus co-infection resulting in polyomavirus nephropathy and progressive multifocal leukoencephalopathy at the same time, a case report [PDF]

Brazilian Journal of Infectious Diseases
John Cunningham Virus (JCV) and BK Virus (BKV) are the most extensively studied Human Polyomaviruses (HPyVs), primarily associated with Progressive Multifocal Leukoencephalopathy (PML) and BKV Nephropathy (BKVN), respectively.
Sébastien Briol, Laura Labriola, Arnaud Devresse, Benoit Kabamba, Valeria Onofrj, Leïla Belkhir   +5 more
doaj   +2 more sources

Single-cell chromatin accessibility landscape of T cell-mediated rejection and BK polyomavirus-associated nephropathy after kidney transplantation. [PDF]

Ren Fail
Both T cell-mediated rejection (TCMR) and BK polyomavirus-associated nephropathy (BKPyVAN) pose significant obstacles to successful kidney transplantation, emphasizing the importance of their accurate diagnosis for prompt medical intervention. Unfortunately, our current understanding of the molecular characteristics of these conditions is still limited,
Zhou J, Wu H, Zhou Q, Fu X, Chen J.
europepmc   +3 more sources

Low 25-Hydroxyvitamin D Post-Kidney Transplant Is Associated with Increased Risk of BK Polyomavirus-Associated Nephropathy. [PDF]

Microorganisms
BK viremia (BKPyV-DNAemia) and nephropathy (BKPyVAN) are significant causes of morbidity and mortality in kidney transplant recipients (KTRs). Vitamin D supports immune function, yet low 25-hydroxyvitamin D [25(OH)D] is common among KTRs. The association between serum 25(OH)D, measured 61 days to 2 years post-transplant, and subsequent incident BKPyV ...
Raj SA, Zhou AL, Fedorova E, Yuan Z, Mandelbrot DA, Astor BC, Parajuli S.   +6 more
europepmc   +4 more sources

Late BK Nephropathy 15 years post kidney transplant following chemotherapy: A case report [PDF]

IDCases
BK Polyomavirus (BKPyV) is an important risk factor for premature graft loss following kidney transplant. Current practice guidelines recommend screening for BK virus DNA for 2 years after kidney transplant as the risk of BK Polyomavirus associated ...
Anum Hamiduzzaman, Jean Hou, Tram Higgins, Pryce Gaynor, Abhirami Shankar, Erik L. Lum   +5 more
doaj   +2 more sources

Urothelial Carcinoma of the Bladder Following BK Virus Infection in a Pediatric Kidney Transplant Recipient. [PDF]

Pediatr Transplant
ABSTRACT Background Urothelial bladder carcinoma is extremely rare in children and its association with BK virus infection remains unclear. Methods We describe the case of an 11‐year‐old girl who developed a urothelial carcinoma of the bladder four years after receiving her first kidney transplant.
Ichas M, Allard L, Harper L, Yacoub M, Madden I, Vérité C, Godron-Dubrasquet A, Harambat J.   +7 more
europepmc   +2 more sources

Histologic versus Molecular Diagnosis of BK Polyomavirus–Associated Nephropathy [PDF]

Clinical Journal of the American Society of Nephrology, 2006
Although discovered in 1970 the BK virus infections had no significant clinical impact until the emergence of BK virus-associated allograft nephropathy (BKPVAN). Escalating clinical challenges required better diagnostic tools and delineation of uniform criteria for diagnosis.
Cinthia B, Drachenberg, John C, Papadimitriou, Emilio, Ramos   +2 more
openaire   +2 more sources

Native BK Polyomavirus Nephropathy in an Orthotopic Heart Transplant Patient

Journal of Investigative Medicine High Impact Case Reports, 2023
BK polyomavirus nephropathy (BKVN) is a common cause of nephropathy in kidney transplant patients and is typically seen within the first year after transplantation.
Zachary M. Thompson MD, George Ajene DO, Prathit A. Kulkarni MD, Nidhi Aggarwal MD, Savitri Fedson MD, Maulin K. Shah MD   +5 more
doaj   +1 more source