Results 31 to 40 of about 2,606 (151)
Background Some studies have suggested mizoribine (MZR) could inhibit the replication of BK polyomavirus (BKPyV). The purpose of this study was to explore whether conversion from mycophenolate mofetil (MMF) to MZR in the early stages of BKPyV infection ...
Ping Li +6 more
doaj +1 more source
BK virus nephropathy in a heart transplant recipient
BK virus nephropathy in kidney transplantation is widely recognized as an important cause of graft dysfunction and loss. In the case of transplants of organs other than kidney, BK virus nephropathy in native kidneys has been recognized as a cause of ...
John Fredy Nieto-Ríos +6 more
doaj +2 more sources
Background BK polyomavirus-associated nephropathy is an important cause of post-transplantation renal failure. We present two cases of BK polyomavirus-associated nephropathy who were submitted to contrasting strategies of clinical follow-up to BK ...
Ana Luisa Figueira Gouvêa +10 more
doaj +1 more source
Simultaneous pancreas/kidney transplant recipients present with late-onset BK polyomavirus-associated nephropathy [PDF]
Infections have increased in simultaneous pancreas/kidney transplant recipients (SPKTRs) with BK polyomavirus (BKV)-associated nephropathy (BKVN) being the most important infectious cause of allograft loss. Comparisons of BKVN with kidney transplant recipients (KTRs), however, are lacking.We studied all SPKTRs and KTRs at our transplant centre between ...
Thomas, Schachtner +3 more
openaire +2 more sources
Polyomavirus-associated nephropathy is an important cause of allograft dysfunction and graft loss after kidney transplantation. Even if histological evaluation is the gold standard for graft study and diagnosis of polyomavirus-associated nephropathy, K ...
Antonio Curtoni +8 more
doaj +1 more source
Renal dysfunction frequently occurs in liver transplant recipients and is associated with increased morbidity and mortality. BK virus is a human polyoma virus that reactivates during immunocompromised states and is a known cause of renal allograft ...
Yangmin Zeng +6 more
doaj +1 more source
HLA-B Leader Dimorphism Predicts BK Polyomavirus Replication After Kidney Transplant. [PDF]
ABSTRACT BK polyomavirus (BKPyV) and Cytomegalovirus (CMV) often replicate after kidney transplantation, with management limited to reducing immunosuppression and risking rejection. Among genetic factors that may modulate the antiviral response, HLA evolutionary divergence (HED, allowing a greater diversity of antigen presentation) and the HLA‐B leader
Aubry A +7 more
europepmc +2 more sources
BK polyomavirus microRNA expression and sequence variation in polyomavirus-associated nephropathy
BK polyomavirus (BKPyV) infection is a common asymptomatic viral infection in the general population. Severe complications are seen in immunocompromised individuals, such as polyomavirus-associated nephropathy (PyVAN) in renal transplant recipients. Information on BKPyV microRNA expressions is scarce, although polyomavirus-encoded microRNAs have been ...
Virtanen, Elina +8 more
openaire +3 more sources
In renal transplantation, BK-virus-associated nephropathy has emerged as a major complication, with a prevalence of 5–10% and graft loss in >50% of cases. BK-virus is a member of the Polyomavirus family and rarely induces apparent clinical disease in the
manon edekeyser +3 more
doaj +1 more source
Surveillance of polyomavirus BK in relation to immunosuppressive therapy in kidney transplantation
Introduction. Reactivation of polyomavirus BK in kidney transplant recipients has been associated to the development of nephropathy (polyomavirus-associated nephropathy, PVAN), possibly leading to the loss of the transplanted organ.
Cristina Costa +8 more
doaj +1 more source

