Results 41 to 50 of about 2,606 (151)

Fluoroquinolone prophylaxis in preventing BK polyomavirus infection after renal transplant: A systematic review and meta-analysis

Kaohsiung Journal of Medical Sciences, 2016
Previous studies regarding the prevention of BK viremia following renal transplantation with fluoroquinolone have yielded conflicting results. The purpose of this systematic review was to examine the evidence regarding the efficacy of fluoroquinolone in ...
Tu-Run Song, Zheng-Sheng Rao, Yang Qiu, Jin-Peng Liu, Zhong-Li Huang, Xian-Ding Wang, Tao Lin   +6 more
doaj   +1 more source

Intragraft Blood Dendritic Cell Antigen-1–Positive Myeloid Dendritic Cells Increase during BK Polyomavirus–Associated Nephropathy [PDF]

Journal of the American Society of Nephrology, 2015
Although both polyomavirus infection and T cell–mediated rejection (TCMR) are characterized by tubulointerstitial inflammation in the renal allograft, these conditions are treated with opposing therapeutic regimens. To gain more insight into the differences between antiviral and alloimmune responses, we performed a case-control study, in which we ...
Yapici, U., Kers, J., Slavujevic-Letic, I., Stokman, G., Roelofs, J.J., Aalderen, M.C. van, Groothoff, J.W., Boer, O.J. de, Pant, K.A. van der, Claessen, N., Hilbrands, L.B., Bemelman, F.J., Berge, I.J. Ten, Florquin, S.   +13 more
openaire   +4 more sources

Molecular Networks Involved in the Immune Control of BK Polyomavirus

Clinical and Developmental Immunology, 2012
BK polyomavirus infection is the important cause of virus-related nephropathy following kidney transplantation. BK virus reactivates in 30%–80% of kidney transplant recipients resulting in BK virus-related nephropathy in 1%–10% of cases.
Eva Girmanova, Irena Brabcova, Jiri Klema, Petra Hribova, Mariana Wohlfartova, Jelena Skibova, Ondrej Viklicky   +6 more
doaj   +1 more source

Comparison of Immunohistochemical Staining for Large T Antigen and Capsid Protein VP1 in BK Polyomavirus-Associated Nephropathy [PDF]

Nephron, 2020
Aim: Most transplant centres use SV40 large T antigen (TAg) staining for the diagnosis and assessment of BK polyomavirus-associated nephropathy (BKPyVAN). This study was performed to evaluate the significance of capsid protein VP1 expression in BKPyVAN. Methods: We performed immunohistochemical staining using anti-SV40 TAg and anti-BKPyV VP1 antibodies
Kosuke Masutani, Yuta Matsukuma, Akihiro Tsuchimoto, Yasuhiro Okabe, Atsushi Doi, Keizo Kaku, Masafumi Nakamura, Toshiaki Nakano, Kazuhiko Tsuruya, Takanari Kitazono   +9 more
openaire   +2 more sources

Complications post renal transplantation: literature focus on BK virus nephropathy and diagnostic tools actually available

Virology Journal, 2008
Clinical diagnosis of kidney transplants related illnesses is not a simple task. Several studies were conducted to define diseases and complications after renal transplantation, but there are no comprehensive guidelines about diagnostic tools for their ...
Miglio Umberto, Boldorini Renzo, Fioriti Daniela, Anzivino Elena, Bellizzi Anna, Mischitelli Monica, Chiarini Fernanda, Di Monaco Franco, Pietropaolo Valeria   +8 more
doaj   +1 more source

Role of BK Virus CTLs in the Treatment of BK Virus–Associated Nephropathy in Kidney‐Transplant and Hematopoietic Cell Transplant Recipients

Transplant Infectious Disease, EarlyView.
Third‐party, BK virus‐specific cytotoxic T lymphocytes (CTLs) were safe and effective in reducing viremia in kidney and stem cell transplant recipients with BK virus nephropathy. However, they did not improve kidney function. Earlier administration may be more beneficial before nephropathy and irreversible damage occur.
Amanda Olson, Ye Ethan Li, Rafet Basar, Pinaki Banerjee, Indresh Kaur, Glorette Abueg, Melihate Sylejmani, Nadima Uprety, Rejeena Shrestha, Francia Reyes Silva, Valda Page, Richard E. Champlin, Dimitrios P. Kontoyiannis, Roy F. Chemaly, Elizabeth J. Shpall, Linda Moore, Osama A. Gaber, Katayoun Rezvani, Ala Abudayyeh   +18 more
wiley   +1 more source

Evaluation of polyomavirus BK reactivation in lupus patients who underwent kidney transplantation

Microbiologia Medica, 2012
Background. A pathogenic role for polyomavirus BK in systemic lupus erythematosus (SLE) has been proposed, however no study evaluated the occurrence of BK replication in renal transplant recipients according to the underlying disease leading to ...
Cristina Costa, Giovanni Antonio Touscoz, Francesca Sidoti, Franca Sinesi, Daniela Re, Cinzia Balloco, Elsa Piasentin Alessio, Maria Messina, Giuseppe Paolo Segoloni, Rossana Cavallo   +9 more
doaj   +1 more source

A highly potent human antibody neutralizing all serotypes of BK polyomavirus.

PLoS Pathogens
BK polyomavirus infection poses a significant risk to kidney transplant recipients. Reactivation of dormant virus in the transplanted kidney, triggered by immunosuppression, can lead to BK polyomavirus-associated nephropathy in up to 10% of transplants ...
Marcel Weber, Simone Schmitt, Barbara Eicher, Jemima Seidenberg, Justina Rutkauskaite, Benedikt Stöckli, Catherine Townsend, Uyen Huynh-Do, Thomas Schachtner, Serena Delbue, Armin Mäder, Christoph Esslinger, Matthias Hillenbrand   +12 more
doaj   +1 more source

Genetic variability of the VP1 gene of BK and JC polyomaviruses in HIV-infected patients [PDF]

Medicinski Podmladak, 2015
Human polyomaviruses, BK virus (BKV) and JC virus (JCV), are world widely distributed in human population. After primary infection, BKV and JCV establish latency in kidneys and upper part of urinary tract. In seropositive healthy individuals asymptomatic
Karalić Danijela, Lazarević Ivana
doaj   +1 more source

BK polyomavirus: latency, reactivation, diseases and tumorigenesis

Frontiers in Cellular and Infection Microbiology, 2023
The identification of the first human polyomavirus BK (BKV) has been over half century, The previous epidemiological and phylogenetic studies suggest that BKV prevailed and co-evolved with humans, leading to high seroprevalence all over the world.
Xianfeng Zhou, Xianfeng Zhou, Xianfeng Zhou, Chunlong Zhu, Hui Li   +4 more
doaj   +1 more source