Results 51 to 60 of about 2,606 (151)
BK virus‐associated urothelial carcinoma—A supra‐regional cohort of kidney transplant recipients
Abstract Objectives This study aims to study the clinical features, pathological findings, and outcomes of BK virus‐associated urothelial carcinoma (UC) in kidney transplant recipients (KTRs). Patients and Methods The study was conducted in a retrospective cohort of KTRs with histologically confirmed UC managed at a UK supra‐regional transplant urology
Noah Beetge +4 more
wiley +1 more source
BKTyper: Free Online Tool for Polyoma BK Virus VP1 and NCCR Typing
Human BK polyomavirus (BKPyV) prevalence has been increasing due to the introduction of more potent immunosuppressive agents in transplant recipients, and its clinical interest. BKPyV has been linked mostly to polyomavirus-associated hemorrhagic cystitis,
Joan Martí-Carreras +5 more
doaj +1 more source
Development of a droplet digital PCR assay for the detection of BK polyomavirus
The objective of this study was to establish a more sensitive and specific diagnostic method for detecting plasma BK polyomavirus (BKPyV) DNA load in patients after renal transplantation using droplet digital polymerase chain reaction (ddPCR) and to ...
Lu Ai +9 more
doaj +1 more source
ABSTRACT Kidney transplantation increases the survival rate of end‐stage renal disease patients; however, acute rejection and glomerulonephritis, such as the uncommon non‐lupus full‐house nephropathy (NLFHN), can lead to graft dysfunction. NLFHN exhibits a characteristic lupus immunofluorescence pattern in the absence of systemic lupus features, which ...
Tala Pourlak, Farahnoosh Farnood
wiley +1 more source
BK Virus Nephropathy: Prevalence, Impact and Management Strategies
Rajeev Sharma,1,2 Mareena Zachariah3 1School of Medicine, University of Nevada Las Vegas, Las Vegas, NV, USA; 2Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA; 3Department of Nephrology, Wayne State University ...
Sharma R, Zachariah M
doaj
Polyomavirus BK Nephropathy-Associated Transcriptomic Signatures: A Critical Reevaluation
Background. Recent work using DNA microarrays has suggested that genes related to DNA replication, RNA polymerase assembly, and pathogen recognition receptors can serve as surrogate tissue biomarkers for polyomavirus BK nephropathy (BKPyVN). Methods.
Ling Pan, MD +7 more
doaj +1 more source
Proteinuria After Kidney Transplantation
ABSTRACT Proteinuria is a relatively frequent complication in both adults and children after kidney transplantation (40%–80%). It is usually mild and predominantly of tubular origin and is caused mainly by rejection, mTOR inhibitors, or hypertension; however, proteinuria could also be in the nephrotic range and of glomerular origin if caused by the ...
Tomas Seeman +6 more
wiley +1 more source
Renal Allograft Biopsies with Polyomavirus BK Nephropathy: Turin Transplant Center, 2015–19
Background: In kidney transplant patients, polyomavirus-associated nephropathy (PVAN) represents a serious complication; the key factor for the development of PVAN is immunosuppression level and modulation of anti-rejection treatment represents the first
Elisa Zanotto +10 more
doaj +1 more source
Human Polyomavirus BK Genome Analysis in BKPyV Induced Rodent Cell Lines
In this study, we analyzed the BK polyomavirus (BKPyV) genome derived from three rodent cell lines established from BKPyV induced tumors. BKPyV derived one cell line had a large deletion. The noncoding control region (NCCR) of BKPyV derived from these cell lines had the same structure as viruses induced tumors.
Setsuko Shioda +6 more
wiley +1 more source
Frequency of Polyomavirus BK Infection in Kidney Transplant Patients Suspected to Nephropathy
Background: Polyomavirus BK is a major cause of nephropathy in immunosuppressed transplanted patients. Non-invasive diagnostic protocols such as molecular detection of polyomavirus BK replication are a useful strategy to predict BK virus-associated ...
M Pakfetrat +5 more
doaj

