Results 1 to 10 of about 1,116 (94)

The Burden of BK Polyomavirus in Pediatric Renal Transplantation: A Belgian Experience [PDF]

Biomedicines
Background/Objectives: To evaluate the outcome of developing BKPyV-DNAemia and presumptive BKPyV-nephropathy (BKPyV-DNAemia ≥ 104 copies/mL for more than 2 weeks) within the first 2 years post-transplant in a Belgian population of renal transplanted ...
Pauline Guillaume-Gentil, Benedetta Chiodini, Brigitte Adams, Jean Herman, Maria Van Dyck, Khalid Ismaili   +5 more
doaj   +2 more sources

Transplant failure in relation to BK viremia status among kidney transplant recipients in Jordan [PDF]

Iranian Journal of Microbiology
Background and Objectives: BK polyomavirus (BKPyV) poses a significant threat to kidney transplant (KT) recipients due to immunosuppression, leading to BK-associated nephropathy (BKVN) and reduced transplant survival.
Rabaa Y. Athamneh, Reema Bani Saeed, Omaymah Abulannaz, Rawan Abudalo, Muna Oqal   +4 more
doaj   +2 more sources

Explorative Insights into Local Immune Response to BK Virus—A Cross-Sectional Study in Urine Samples Between Transplant Recipients and Non-Immunocompromised Hosts [PDF]

Medicina
Background and Objectives: BK virus (BKPyV) is a common latent pathogen in humans, but it becomes particularly insidious in kidney transplant recipients, where reactivation may contribute to allograft loss. The immune mechanisms controlling BKPyV latency
Agata Michnowska, Bartosz Wojciuk, Paulina Reus, Agata Filipowska, Magdalena Mnichowska-Polanowska, Bartłomiej Grygorcewicz, Kazimierz Ciechanowski, Karolina Kędzierska-Kapuza   +7 more
doaj   +2 more sources

Prolonged Prophylactic Ureteral Stent Placement and BK Polyomavirus Infection After Renal Transplantation—A Retrospective Case-control Study [PDF]

European Urology Open Science
Background and objective: BK polyomavirus (BKPyV) poses a significant challenge in kidney transplant (KTX) recipients, potentially leading to BKPyV-associated nephropathy.
Haris Omić, Simon Hoffmann, Michael Eder, Robert Strassl, Daniela Gerges, Shahrokh F. Shariat, Željko Kikić   +6 more
doaj   +2 more sources

ISG20 Restricts BK Polyomavirus Infection and Engages in Reciprocal Regulation with Viral Large T Antigen [PDF]

Microorganisms
BK polyomavirus (BKPyV) causes severe urinary tract diseases, including BKPyV-associated nephropathy (BKPyVN) and ureteric stenosis, in immunocompromised individuals such as renal transplant recipients.
Yumin Hou, Chunlan Hu, Yejing Shi, Xiaohui Zhou, Tongyu Zhu, Nannan Wu   +5 more
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Clinical Associations and Coexistence of Polyomavirus DNAemia with EBV and CMV in Pediatric Hematology/Oncology Patients, Including HCT Recipients—A Pilot Study [PDF]

Pathogens
Polyomaviruses (BKPyV and JCPyV) and herpesviruses (EBV, CMV) usually infect people during childhood, and may be associated, in some clinical states, with immunocompromised individuals.
Tomasz Bogiel, Mateusz Rzepka, Dagmara Depka-Radzikowska, Patrycja Zalas-Więcek, Krzysztof Czyżewski, Monika Richert-Przygońska, Jan Styczyński, Robert Dębski, Elżbieta Grześk, Grzegorz Grześk, Piotr Kanarek, Agnieszka Krawczyk   +11 more
doaj   +2 more sources

Pretransplantation seroreactivity in kidney donors and recipients as a predictive factor for posttransplant BKPyV-DNAemia

Frontiers in Immunology, 2022
BK polyomavirus (BKPyV) often reactivates after kidney transplantation, causing BKPyV-associated nephropathy (BKPyVAN) in 1%–10% of cases with a potential detrimental effect on allograft survival.
Martina Saláková, Viera Ludvíková, Eva Hamšíková, Marie Kolářová, Vojtěch Šroller, Ondřej Viklický, Mariana Wohlfahrtová   +6 more
doaj   +1 more source

BKPyV DNAemia in Kidney Transplant Recipients Undergoing Regular Screening: A Single-Centre Cohort Study

Microorganisms, 2023
Infection with BK polyomavirus (BKPyV) is a common opportunistic infection after kidney transplantation (KT) and may affect graft function. We aimed to determine the incidence, risk factors, and clinical outcomes of BKPyV DNAemia in a prospective cohort ...
Daniel B. Rasmussen, Dina L. Møller, Sebastian R. Hamm, Álvaro H. Borges, Alex C. Y. Nielsen, Nikolai S. Kirkby, Søren S. Sørensen, Susanne D. Nielsen   +7 more
doaj   +1 more source

Pretransplant BK Virus-Specific T-Cell-Mediated Immunity and Serotype Specific Antibodies May Have Utility in Identifying Patients at Risk of BK Virus-Associated Haemorrhagic Cystitis after Allogeneic HSCT

Vaccines, 2021
BK polyomavirus (BKPyV) persists lifelong in renal and urothelial cells with asymptomatic urinary shedding in healthy individuals. In some immunocompromised persons after transplantation of hematopoietic stem cells (HSCT), the BKPyV high-rate replication
Markéta Šťastná-Marková, Eva Hamšíková, Petr Hainz, Petr Hubáček, Marie Kroutilová, Jitka Kryštofová, Viera Ludvíková, Jan Musil, Pavla Pecherková, Martina Saláková, Vojtěch Šroller, Jan Vydra, Šárka Němečková   +12 more
doaj   +1 more source

A systematic review. Current understanding of the infection caused by Betapolyomavirus hominis

Журнал инфектологии, 2023
Reactivation of Betapolyomavirus hominis (BKPyV) in kidney and hematopoietic stem cell recipients can lead to serious complications such as BKPyV-associated nephropathy followed by transplant rejection and BKPyV-associated hemorrhagic cystitis.
D. R. Prilepskaya, E. A. Domonova
doaj   +1 more source