Results 91 to 100 of about 2,195 (192)

Allogeneic CD4 T Cells Sustain Effective BK Polyomavirus-Specific CD8 T Cell Response in Kidney Transplant Recipients

Kidney International Reports
Introduction: BK polyomavirus-associated nephropathy (BKPyVAN) is a significant complication in kidney transplant recipients (KTRs), associated with a higher level of plasmatic BK polyomavirus (BKPyV) replication and leading to poor graft survival ...
Manon Dekeyser, Marie-Ghislaine de Goër de Herve, Houria Hendel-Chavez, Romain Lhotte, Ivan Scriabine, Karen Bargiel, Emmanuelle Boutin, Florence Herr, Jean-Luc Taupin, Yassine Taoufik, Antoine Durrbach   +10 more
doaj   +1 more source

Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review

European Journal of Clinical Investigation, Volume 55, Issue 8, August 2025.
Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina, Fábio França Vieira e Silva, Rafael Antônio Velôso Caixeta, Bruna de Oliveira Rech, Alba Perez‐Jardón, María Elena Padín‐Iruegas, Mario Pérez‐Sayáns, Paulo Henrique Braz‐Silva, Karem L. Ortega   +8 more
wiley   +1 more source

BKTyper: Free Online Tool for Polyoma BK Virus VP1 and NCCR Typing

Viruses, 2020
Human BK polyomavirus (BKPyV) prevalence has been increasing due to the introduction of more potent immunosuppressive agents in transplant recipients, and its clinical interest. BKPyV has been linked mostly to polyomavirus-associated hemorrhagic cystitis,
Joan Martí-Carreras, Olga Mineeva-Sangwo, Dimitrios Topalis, Robert Snoeck, Graciela Andrei, Piet Maes   +5 more
doaj   +1 more source

Multiplex analysis of Human Polyomavirus diversity in kidney transplant recipients with BK virus replication [PDF]

, 2019
Background: While the pathogenicity of the two initially identified Human Polyomaviruses (HPyVs), BK Virus (BKPyV) and JC Virus (JCPyV) has been intensely studied, there is only limited data, on whether the occurrence of the recently discovered HPyVs ...
Aberle, Stephan W., Bond, Gregor, Hedman, Klaus, Helanterä, Ilkka, Strassl, Robert, Wang, Yilin, Weseslindtner, Lukas   +6 more
core   +1 more source

Caveolin- and clathrin-independent entry of BKPyV into primary human proximal tubule epithelial cells

Virology, 2016
BK polyomavirus (BKPyV) is a human pathogen that causes polyomavirus-associated nephropathy and hemorrhagic cystitis in transplant patients. Gangliosides and caveolin proteins have previously been reported to be required for BKPyV infection in animal cell models.
Linbo, Zhao, Anthony T, Marciano, Courtney R, Rivet, Michael J, Imperiale   +3 more
openaire   +2 more sources

Management of Trichodysplasia Spinulosa in a Pediatric Kidney Transplant Patient With Topical Cidofovir and Oral Leflunomide

Pediatric Transplantation, Volume 29, Issue 3, May 2025.
ABSTRACT Background This case report describes a 10‐year‐old male with a history of kidney transplantation who developed trichodysplasia spinulosa (TS), a rare skin disorder associated with immunosuppression. Methods The patient's condition, characterized by follicular papules and keratinous spines primarily on the face, was managed by a ...
Annika M. Hansen, Sonia Mehra, Anneli R. Bowen, Joseph Sherbotie, Sarah D. Cipriano   +4 more
wiley   +1 more source

Genetic polymorphisms in TLR3, IL10 and CD209 influence the risk of BK polyomavirus infection after kidney transplantation

Scientific Reports, 2022
Genetic determinants of BK polyomavirus infection after kidney transplantation remain poorly investigated. We assessed the potential impact of 13 different single nucleotide polymorphisms within genes mainly involved in innate immune responses on the ...
Natalia Redondo, Isabel Rodríguez-Goncer, Patricia Parra, Francisco López-Medrano, Esther González, Ana Hernández, Hernando Trujillo, Tamara Ruiz-Merlo, Rafael San Juan, María Dolores Folgueira, Amado Andrés, José María Aguado, Mario Fernández-Ruiz   +12 more
doaj   +1 more source

Human Polyomaviruses in the Cerebrospinal Fluid of Neurological Patients. [PDF]

, 2020
BACKGROUND: Central nervous system (CNS) infections by human polyomaviruses (HPyVs), with the exception of JC (JCPyV), have been poorly studied. METHODS: In total, 234 cerebrospinal fluid (CSF) samples were collected from patients affected with ...
Campisciano, G, Ciotti, M, Comar, M, D'Alessandro, S, Delbue, S, Dolci, M, Ferrante, P, Franciotta, D, Giannella, S, Signorini, L, Ticozzi, R   +10 more
core   +2 more sources

Humán papillomavírus és humán herpeszvírusok kóroki szerepének molekuláris vizsgálata = Molecular analysis of pathogenic role of human papilloma virus and human herpesviruses [PDF]

, 2013
Vesetranszplantáltak mintáiban a humán herpeszvírus 6A dominanciáját, és a humán cytomegalovírussal megegyező gyakoriságát találtuk. Az új KI és WU polyomavírusok jelenlétét mi írtuk le először vizeletből, a HPyV9-et légúti mintákból.
Csoma, Eszter, Gergely, Lajos, Murvai, Melinda, Szarka, Krisztina Zsuzsanna   +3 more
core  

Longitudinal assessment of the CXCL10 blood and urine concentration in kidney transplant recipients with BK polyomavirus replication—a retrospective study [PDF]

, 2020
In kidney transplant recipients (KTRs), BK polyomavirus (BKPyV) replication may progress to polyomavirus-associated nephropathy (PVAN). In this retrospective study, we assessed the chemokine CXCL10 in urine and blood samples consecutively acquired from ...
Aberle, Stephan W., Bond, Gregor, Hedman, Klaus, Hedman, Lea, Helanterä, Ilkka, Strassl, Robert, Wang, Yilin, Weseslindtner, Lukas   +7 more
core   +1 more source