Results 51 to 60 of about 2,195 (192)

Human polyomaviruses in children undergoing transplantation, United States, 2008-2010 [PDF]

, 2012
Immunocompromised patients are at risk for disease caused by infection by some polyomaviruses. To define the prevalence of polyomaviruses in children undergoing transplantation, we collected samples from a longitudinal cohort and tested for the 9 known ...
Bauer, Irma, Canter, Charles, Hmiel, Paul, Holtz, Lori R, Lassa-Claxton, Sherry, Le, Binh-minh, Shenoy, Shalini, Shepherd, Ross, Siebrasse, Erica A, Sweet, Stuart, Turmelle, Yumirle, Wang, David   +11 more
core   +2 more sources

Multiplex detection in tonsillar tissue of all known human polyomaviruses [PDF]

, 2017
Background: In the past few years, eleven new human viruses have joined the two previously known members JCPyV and BKPyV of the Polyomaviridae family, by virtue of molecular methods. Serology data suggest that infections with human polyomaviruses (HPyVs)
Aaltonen, Leena-Maija, Hedman, Klaus, Pyöriä, Lari, Ramqvist, Torbjorn, Sadeghi, Mohammadreza, Soderlund-Venermo, Maria, Toppinen, Mari, Wang, Yilin   +7 more
core   +1 more source

Agnoprotein of polyomavirus BK interacts with proliferating cell nuclear antigen and inhibits DNA replication [PDF]

, 2015
License:Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)Background: The human polyomavirus BK expresses a 66 amino-acid peptide referred to as agnoprotein.
Barbara van Loon, Conny Tümmler, Elena Ferrari, Igor Snapkov, Mari Walquist, Mona Johannessen, Nancy Gerits, Sergiy Kostenko, Ugo Moens, Ulrich Hübscher   +9 more
core   +2 more sources

A Phase I Study Evaluating Safety and Tolerability of Viral-Specific T Cells Against BK-Virus in Adult Kidney Transplant Recipients. [PDF]

J Med Virol
ABSTRACT BK polyomavirus (BKPyV) poses a significant threat to kidney transplant recipients (KTR). Current management primarily involves reducing immunosuppression, which increases the risk of rejection. Cell‐based immunotherapy with virus‐specific T cells (VST) has emerged as an alternative approach for treating BKPyV in KTRs. This single‐center phase
Ptak L, Meyers RO, Radko-Ganz O, McDowell KA, Jorgenson M, Chilsen M, Mandelbrot D, Galipeau J, Parajuli S.   +8 more
europepmc   +2 more sources

Neurological Disease-Affected Patients, including Multiple Sclerosis, Are Poor Responders to BKPyV, a Human Polyomavirus

Journal of Immunology Research, 2022
Multiple sclerosis (MS) is a neurological disease characterized by immune dysregulations. Different viruses may act as MS triggering agents. MS patients respond differently to distinct viruses. The aim of our study is to verify the association between the polyomavirus BKPyV and MS, together with other neurological diseases, through the investigation of
Bononi, Ilaria, Mazzoni, Elisa, Pietrobon, Silvia, Iaquinta, Maria Rosa, Caselli, Andrea, Torreggiani, Elena, Pugliatti, Maura, Casetta, Ilaria, Castellazzi, Massimiliano, Granieri, Enrico, Martini, Fernanda, Tognon, Mauro   +11 more
openaire   +4 more sources

In Vitro Generation of BK polyomavirus-specific T cells for adoptive cell therapy in refractory cystitis hemorrhagic patients after hematopoietic stem cell transplantation

BMC Immunology, 2022
Introduction BKPyV associated hemorrhagic cystitis (BKPyV-HC) is a major and prevalent outcome of hematopoietic stem cell transplantation (HSCT) with no standard treatment option.
Maryam Mohammadi Najafabadi, Masoud Soleimani, Mohammad Ahmadvand, Mina Soufi Zomorrod, Seied Asadollah Mousavi   +4 more
doaj   +1 more source

Identification of a novel human polyomavirus in organs of the gastrointestinal tract [PDF]

, 2013
Peer reviewedPublisher ...
Calvignac-Spencer, Sebastien, Ehlers, Bernhard, Hofmann, Jorg, Korup, Sarah, Moens, Ugo, Rietscher, Janita, Sauer, Igor, Schmuck, Rosa, Trusch, Franziska, Voigt, Sebastian   +9 more
core   +4 more sources

Seroprevalence of polyomaviruses BK and JC in Finnish women and their spouses followed-up for three years

Scientific Reports, 2023
BK (BKPyV) and JC (JCPyV) polyomavirus infections are commonly subclinical and known infrequently to cause serious clinical diseases. Longitudinal follow-up studies regarding JCPyV and BKPyV serological outcomes are scanty.
Hanna K. Laine, Tim Waterboer, Kari Syrjänen, Seija Grenman, Karolina Louvanto, Stina Syrjänen   +5 more
doaj   +1 more source

Chk1 and the Host Cell DNA Damage Response as a Potential Antiviral Target in BK Polyomavirus Infection

Viruses, 2021
The human BK polyomavirus (BKPyV) is latent in the kidneys of most adults, but can be reactivated in immunosuppressed states, such as following renal transplantation.
Lydia E. Hainley, Martina S. Hughson, Amithi Narendran, Ralph Smith, Justin Arthur, Alida Hayner-Buchan, David J. Conti, John M. Lehman, Thomas D. Friedrich   +8 more
doaj   +1 more source

Review on the role of the human Polyomavirus JC in the development of tumors [PDF]

, 2017
Almost one fifth of human cancers worldwide are associated with infectious agents, either bacteria or viruses, and this makes the possible association between infections and tumors a relevant research issue.
Manola Comar, Pasquale Ferrante, Serena Delbue   +2 more
core   +1 more source