On why cancer cells require a great amount of glucose
Quantitative Biology, Volume 14, Issue 2, June 2026.Abstract The traditional thinking has been that cancer cells require a great amount of glucose to support their rapid growth, but the reality may be different. We have previously demonstrated that all cancer cells in The Cancer Genome Atlas harbor persistent Fenton reactions in their cytosol, which generate OH− ${\text{OH}}^{-}$ and ultimately kill the
Xuechen Mu +6 more
wiley +1 more source
INTEGRATIVE ANALYSIS OF OMICS DATA IN ADULT GLIOMA AND OTHER TCGA CANCERS TO GUIDE PRECISION MEDICINE [PDF]
, 2017 Transcriptomic profiling and gene expression signatures have been widely applied as effective approaches for enhancing the molecular classification, diagnosis, prognosis or prediction of therapeutic response towards personalized therapy for cancer ...
hu, Xin, hu, xin
core +1 more source
The role of a new class of long noncoding RNAs transcribed from ultraconserved regions in cancer [PDF]
, 2017 Ultraconserved regions (UCRs) represent a relatively new class of non-coding genomic sequences highly conserved between human, rat and mouse genomes.
Calin, George A. +5 more
core +1 more source
A Simple and Fast Method for Derivation of Blastocyst-Like Cell Aggregates (BLCAs) from Murine Embryonic Stem Cells [PDF]
Journal of Biomaterials and Tissue Engineering, 2018 The study of blastocyst differentiation from stem cells is still at its stage of infancy. In this study, a simple and efficient method was developed to derive blastocyst-like cell aggregates (BLCAs) from murine embryonic stem cells (mESCs). This was achieved by culturing the mESCs in non-adherent dishes.0020BLCAs (13±2 per million mESCs) were obtained ...
Jung Kyu, Choi, Xiaoming, He
openaire +2 more sources
His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models
Advanced Science, Volume 13, Issue 19, 2 April 2026.His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li +13 more
wiley +1 more source
CXCL10 could be a prognostic and immunological biomarker in bladder cancer
Discover OncologyIntroduction As proteins that promote immune cell differentiation, chemokines have attracted great interest regarding their role in anti-tumor immune responses within the cancer environment.
Tao Yin +7 more
doaj +1 more source
Implementasi Blended Learning by the Constructive Approach (BLCA) untuk Meningkatkan Pemahaman Konsep dan Kemandirian Belajar Mahasiswa dalam Matakuliah Interaksi Manusia dan Komputer Prodi Teknologi Pendidikan FIP UNY [PDF]
, 2013 Penelitian ini bertujuan untuk: 1) mengetahui implementasi blended learning by the constructive approach (BLCA) dalam matakuliah Interaksi Manusia dan Komputer (IMK) Prodi Teknologi Pendidikan (TP) FIP UNY; 2) meningkatkan pemahaman konsep mahasiswa ...
Wahyuningsih, dian
core
Corruption of the Intra-Gene DNA Methylation Architecture Is a Hallmark of Cancer [PDF]
, 2013 Epigenetic processes - including DNA methylation - are increasingly seen as having a fundamental role in chronic diseases like cancer. It is well known that methylation levels at particular genes or loci differ between normal and diseased tissue. Here we
Bartlett, TE +5 more
core +3 more sources
The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases
MedComm, Volume 7, Issue 4, April 2026.Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi +5 more
wiley +1 more source
Transcriptome Analyses of Tumor-Adjacent Somatic Tissues Reveal Genes Co-Expressed with Transposable Elements [PDF]
, 2019 Background: Despite the long-held assumption that transposons are normally only expressed in the germ-line, recent evidence shows that transcripts of transposable element (TE) sequences are frequently found in the somatic cells.
Alberto, Adrian +9 more
core +2 more sources