Results 41 to 50 of about 15,201 (184)

Comprehensive analysis of normal adjacent to tumor transcriptomes. [PDF]

open access: yes, 2017
Histologically normal tissue adjacent to the tumor (NAT) is commonly used as a control in cancer studies. However, little is known about the transcriptomic profile of NAT, how it is influenced by the tumor, and how the profile compares with non-tumor ...
Aran, Dvir   +8 more
core   +3 more sources

Pan-cancer classifications of tumor histological images using deep learning [PDF]

open access: yes, 2020
Histopathological images are essential for the diagnosis of cancer type and selection of optimal treatment. However, the current clinical process of manual inspection of images is time consuming and prone to intra- and inter-observer variability. Here we
Caruana, Dennis   +8 more
core   +1 more source

The role of the BLCA-4 nuclear matrix protein in bladder cancer

open access: yesPostępy Higieny i Medycyny Doświadczalnej, 2017
Bladder cancer (BC) affects usually older people. According to information provided by the National Cancer Registry in 2012. BC was the 4th, in terms of illness, cancer in men and 11th in women. Early diagnosis of bladder cancer is important because detected later has worse prognosis.Diagnosis of bladder cancer is not simple and it is still very ...
Beata, Szymańska, Anna, Długosz
openaire   +2 more sources

Immune-related long non-coding RNA signature identified prognosis and immunotherapeutic efficiency in bladder cancer (BLCA) [PDF]

open access: yesCancer Cell International, 2020
Abstract Background As bladder cancer was recognized to be immunogenic, dozens of studies have focused on immune biology of BLCA, but little is known about its relationship with the long non-coding RNAs (lncRNAs). Methods LASSO Cox regression model was used to establish ...
Rui Cao   +4 more
openaire   +3 more sources

CDCOCA: A statistical method to define complexity dependence of co-occuring chromosomal aberrations [PDF]

open access: yes, 2011
Background Copy number alterations (CNA) play a key role in cancer development and progression. Since more than one CNA can be detected in most tumors, frequently co-occurring genetic CNA may point to cooperating cancer related genes.
Baudis, Michael   +3 more
core   +1 more source

Role of anoikis-related gene RAC3 in prognosis, immune microenvironment, and contribution to malignant behavior in vitro and in vivo of bladder urothelial carcinoma

open access: yesFrontiers in Pharmacology
BackgroundAnoikis disrupts the normal apoptotic process in cells, leading to abnormal proliferation and migration, thereby promoting tumor formation and development.
Yusong Zhou   +5 more
doaj   +1 more source

Post-transcriptional knowledge in pathway analysis increases the accuracy of phenotypes classification [PDF]

open access: yes, 2016
Motivation: Prediction of phenotypes from high-dimensional data is a crucial task in precision biology and medicine. Many technologies employ genomic biomarkers to characterize phenotypes.
Acunzo, Mario   +5 more
core   +3 more sources

Apoptosis related genes mediated molecular subtypes depict the hallmarks of the tumor microenvironment and guide immunotherapy in bladder cancer

open access: yesBMC Medical Genomics, 2023
Apoptosis has been discovered as a mechanism of cell death. The purpose of this study is to identify the diagnostic signature factors related to bladder cancer (BLCA) through apoptosis related genes (ARGs).
Liquan Zhou   +5 more
doaj   +1 more source

New Cross-Talk Layer between Ultraconserved Non-Coding RNAs, MicroRNAs and Polycomb Protein YY1 in Bladder Cancer [PDF]

open access: yes, 2016
MicroRNAs (miRNAs) are highly conserved elements in mammals, and exert key regulatory functions. Growing evidence shows that miRNAs can interact with another class of non-coding RNAs, so-called transcribed ultraconserved regions (T-UCRs), which take part
Castaldo, Luigi   +10 more
core   +2 more sources

What killed Frame Lake? A precautionary tale for urban planners [PDF]

open access: yes, 2018
Frame Lake, located within the city of Yellowknife, Northwest Territories, Canada, has been identified as requiring significant remediation due to its steadily declining water quality and inability to support fish by the 1970s.
Cott, Peter A.   +7 more
core   +2 more sources

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