A Simple and Fast Method for Derivation of Blastocyst-Like Cell Aggregates (BLCAs) from Murine Embryonic Stem Cells [PDF]
Journal of Biomaterials and Tissue Engineering, 2018 The study of blastocyst differentiation from stem cells is still at its stage of infancy. In this study, a simple and efficient method was developed to derive blastocyst-like cell aggregates (BLCAs) from murine embryonic stem cells (mESCs). This was achieved by culturing the mESCs in non-adherent dishes.0020BLCAs (13±2 per million mESCs) were obtained ...
Jung Kyu, Choi, Xiaoming, He
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Implementasi Blended Learning by the Constructive Approach (BLCA) untuk Meningkatkan Pemahaman Konsep dan Kemandirian Belajar Mahasiswa dalam Matakuliah Interaksi Manusia dan Komputer Prodi Teknologi Pendidikan FIP UNY [PDF]
, 2013 Penelitian ini bertujuan untuk: 1) mengetahui implementasi blended learning by the constructive approach (BLCA) dalam matakuliah Interaksi Manusia dan Komputer (IMK) Prodi Teknologi Pendidikan (TP) FIP UNY; 2) meningkatkan pemahaman konsep mahasiswa ...
Wahyuningsih, dian
core
The role of a new class of long noncoding RNAs transcribed from ultraconserved regions in cancer [PDF]
, 2017 Ultraconserved regions (UCRs) represent a relatively new class of non-coding genomic sequences highly conserved between human, rat and mouse genomes.
Calin, George A. +5 more
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CXCL10 could be a prognostic and immunological biomarker in bladder cancer
Discover OncologyIntroduction As proteins that promote immune cell differentiation, chemokines have attracted great interest regarding their role in anti-tumor immune responses within the cancer environment.
Tao Yin +7 more
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Corruption of the Intra-Gene DNA Methylation Architecture Is a Hallmark of Cancer [PDF]
, 2013 Epigenetic processes - including DNA methylation - are increasingly seen as having a fundamental role in chronic diseases like cancer. It is well known that methylation levels at particular genes or loci differ between normal and diseased tissue. Here we
Bartlett, TE +5 more
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BMC Cancer, 2021 Background Bladder cancer (BLCA) typically has a poor prognosis due to high relapse and metastasis rates. A growing body of evidence indicates that N6-methyladenosine (m6A) and long non-coding RNAs (lncRNAs) play crucial roles in the progression of BLCA ...
Tianming Ma +7 more
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Transcriptome Analyses of Tumor-Adjacent Somatic Tissues Reveal Genes Co-Expressed with Transposable Elements [PDF]
, 2019 Background: Despite the long-held assumption that transposons are normally only expressed in the germ-line, recent evidence shows that transcripts of transposable element (TE) sequences are frequently found in the somatic cells.
Alberto, Adrian +9 more
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Network-based stratification analysis of 13 major cancer types using mutations in panels of cancer genes. [PDF]
, 2015 BACKGROUND: Cancers are complex diseases with heterogeneous genetic causes and clinical outcomes. It is critical to classify patients into subtypes and associate the subtypes with clinical outcomes for better prognosis and treatment.
Li, Bingshan +4 more
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A metabolic reprogramming-related gene signature correlates with prognosis and proliferation of BLCA
Discover OncologyBladder cancer (BLCA) is one of the most frequent urothelium carcinoma, but with poor prognosis due to lack of reliable predictive biomarkers. Metabolic reprogramming involving in various nutrients, and is reported to be closely associated with malignant progression in BLCA.
Yaoxin Wu, Yi Luo, Tinghao Li
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Mitochondrial DNA copy number variation across human cancers. [PDF]
, 2016 Mutations, deletions, and changes in copy number of mitochondrial DNA (mtDNA), are observed throughout cancers. Here, we survey mtDNA copy number variation across 22 tumor types profiled by The Cancer Genome Atlas project.
Al-Ahmadie, Hikmat A +10 more
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