Results 131 to 140 of about 34,526 (257)
Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle
Advanced Functional Materials, EarlyView.This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang +18 more
wiley +1 more source
The End-lock Rule for Exact Extraction of Odd Roots
A familiar cube-root puzzle recovers a two-digit root from the leading three-digit block and the final digit of a perfect cube. We place that observation in a general framework.
Rogen A. Doronila
core +1 more source
Laminated Dough, the Lock in 3 Process, Stage #1 Pastry Making
, 2020 Locking a pre-prepared block of butter between two or more sheets of dough is known as the Lock-in stage in laminated pastry making. James Griffin, Masterbaker explains the process known as a Lock-in 3, the first stage of laminated pastry production ...
Griffin, James A.
core
“Cell Disk” DNA Storage System Capable of Random Reading and Rewriting
Advanced ScienceDNA has emerged as an appealing material for information storage due to its great storage density and durability. Random reading and rewriting are essential tasks for practical large‐scale data storage.
Zhaohua Hou +12 more
doaj +1 more source
Advanced Functional Materials, EarlyView.An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal +21 more
wiley +1 more source
Targeting and Reversing HIV Latency Using Novel 'Block and Lock' Strategies: A Comprehensive Review
The establishment of latent HIV reservoirs remains the principal barrier to achieving a cure for HIV infection. While antiretroviral therapy (ART) effectively suppresses viral replication, it cannot eliminate integrated proviral DNA that persists in a transcriptionally silent state within long-lived memory CD4+ T cells.
openaire +1 more source
Electrically Induced Phase Transition and Synaptic Functionality in MoTe2/Graphene Memristors
Advanced Functional Materials, EarlyView.An electrically induced reversible 2H ↔ 1T′ phase transition is demonstrated in a vertical Au/Ti/MoTe2/graphene memristor with a laterally contacted graphene electrode. Resistive switching proceeds through a compositionally invariant amorphous/2H ↔ amorphous/1T′ transformation, in which a self‐formed amorphous MoTe2 interfacial region is proposed to ...
Chien‐Hua Wang +7 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Inspired by metal‐free carbonic anhydrases (CAs) that achieve efficient catalysis without metal cofactors, we herein report a sequence‐defined supramolecular peptoid platform that mimics metal‐free CAs and exhibits hydrolytic activity via a supramolecular assembly‐mediated proton‐transfer mechanism.
Progyateg Chakma +8 more
wiley +1 more source
Lessee's Plaque, Rebuilding, Lock 11, Lockville
One black and white photographic print mounted to card of a white stone block in a lock wall, probably Lock 11 or Lock 13 on the Ohio and Erie Canal in Lockville in Fairfield County, Ohio that contains writing identified as a ""Lessee's Plaque."
Canal Society of Ohio
core
Advanced Functional Materials, EarlyView.This work presents a closed‐loop optimization workflow integrating CatBot, an automated synthesis and testing system, to discover NiMo hydrogen‐evolution catalysts. CatBot synthesised and evaluated 228 unique samples, identifying the best performing catalysts for transfer to nickel‐foam electrodes. The best candidate is highly active, reaching 1 Acm−2${
Paolo Vincenzo Freiesleben de Blasio +7 more
wiley +1 more source