Blood–brain and blood–cerebrospinal fluid barrier permeability in spontaneously hypertensive rats
Background Hypertension is an important risk factor for cerebrovascular disease, including stroke and dementia. Both in humans and animal models of hypertension, neuropathological features such as brain atrophy and oedema have been reported.
Daphne M. P. Naessens +3 more
doaj +2 more sources
Review of "The Blood-Cerebrospinal Fluid Barrier" by Wei Zheng and Adam Chodobski (editors)
This multi-author volume on the blood-cerebrospinal fluid barrier summarizes past and current research in the areas of choroid plexus and cerebrospinal fluid in health and disease.
Jones Hazel C
doaj +2 more sources
Embryonic Blood-Cerebrospinal Fluid Barrier Formation and Function [PDF]
During embryonic development and adult life, brain cavities and ventricles are filled with cerebrospinal fluid (CSF). CSF has attracted interest as an active signaling medium that regulates brain development, homeostasis and disease.
David eBueno +3 more
doaj +3 more sources
High Blood Pressure Effects on the Blood to Cerebrospinal Fluid Barrier and Cerebrospinal Fluid Protein Composition: A Two-Dimensional Electrophoresis Study in Spontaneously Hypertensive Rats [PDF]
The aim of the present work is to analyze the cerebrospinal fluid proteomic profile, trying to find possible biomarkers of the effects of hypertension of the blood to CSF barrier disruption in the brain and their participation in the cholesterol and β ...
Ibrahim González-Marrero +8 more
doaj +2 more sources
Drug transport in brain
The human brain has no lymphatic system, but produces over a half-liter each day of cerebrospinal fluid. The cerebrospinal fluid is secreted at the choroid plexus and occupies the cavities of the four ventricles, as well as the cranial and spinal sub ...
Pardridge William M
doaj +2 more sources
SARS-CoV-2 infects epithelial cells of the blood-cerebrospinal fluid barrier rather than endothelial cells or pericytes of the blood-brain barrier. [PDF]
BACKGROUND As a consequence of SARS-CoV-2 infection various neurocognitive and neuropsychiatric symptoms can appear, which may persist for several months post infection.
Stüdle C +12 more
europepmc +2 more sources
The blood brain barrier and Lina Solomonovna Stern (Shtern)
The blood–brain barrier (BBB) regulates the transport of molecules between the central nervous system (CNS) and blood. It consists of two components: the vascular endothelial cells forming so–called tight junctions, and the blood–cerebrospinal fluid ...
JMS Pearce
doaj +1 more source
Astroglia support, regulate and reinforce brain barriers
Nervous system is segregated from the body by the complex system of barriers. The CNS is protected by (i) the blood–brain and blood-spinal cord barrier between the intracerebral and intraspinal blood vessels and the brain parenchyma; (ii) the arachnoid ...
Alexei Verkhratsky, Augustas Pivoriūnas
doaj +1 more source
Advances in the Mechanism of Enriched Environment Improving Chronic Cerebral Hypoperfusion-induced Cognitive Impairment [PDF]
Chronic cerebral hypoperfusion-induced cognitive impairment (CCHCI) is a cognitive deficit caused by cerebral cortex or subcortical infarction, white matter degeneration, blood-cerebrospinal fluid barrier, and hippocampal injury due to long-term ...
Huanhuan LIU, Jing GAO, Kaiqi SU, Xiaodong FENG
doaj +1 more source
Expansion of neopterin and beta2-microglobulin in cerebrospinal fluid reaches maximum levels early and late in the course of human immunodeficiency virus infection [PDF]
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Bogner, Johannes R. +5 more
core +1 more source

