Protocol to analyze the transmigration efficiency of T. brucei using an in vitro model of the blood-cerebrospinal fluid barrier [PDF]
STAR Protocols, 2022 Summary: At present, the only approach to investigate the transmigration of Trypanosoma brucei, the causative agent of human African trypanosomiasis, from blood to cerebrospinal fluid is through animal experiments.
Alexander Herrmann +5 more
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Non-Invasive MRI of Blood–Cerebrospinal Fluid Barrier Function [PDF]
Nature Communications, 2020 The blood–cerebrospinal fluid barrier (BCSFB) is an important interface for brain homeostasis. Here the authors describe a non-invasive MRI technique for the quantitative assessment of BCSFB function.
P. G. Evans +10 more
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Simulated microgravity‐induced dysregulation of cerebrospinal fluid immune homeostasis by disrupting the blood–cerebrospinal fluid barrier [PDF]
Brain and BehaviorBackground The blood–cerebrospinal fluid barrier (BCSFB) comprises the choroid plexus epithelia. It is important for brain development, maintenance, function, and especially for maintaining immune homeostasis in the cerebrospinal fluid (CSF).
Jing Yang +11 more
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Choroid plexus and the blood–cerebrospinal fluid barrier in disease [PDF]
Fluids and Barriers of the CNS, 2020 The choroid plexus (CP) forming the blood–cerebrospinal fluid (B-CSF) barrier is among the least studied structures of the central nervous system (CNS) despite its clinical importance.
Peter Solár +4 more
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Linking peripheral low-grade inflammation and blood-cerebrospinal fluid barrier leakage in schizophrenia spectrum disorders – A retrospective analysis [PDF]
Brain, Behavior, & Immunity - HealthBackground: Social impairments and low-grade inflammation (LGI) are associated with psychotic disorders (e.g. schizophrenia spectrum disorders). Social impairments are important symptoms of the disease nonetheless a disturbed social interaction and ...
Timo Jendrik Faustmann +5 more
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Investigating changes in blood-cerebrospinal fluid barrier function in a rat model of chronic hypertension using non-invasive magnetic resonance imaging [PDF]
Frontiers in Molecular Neuroscience, 2022 Chronic hypertension is a major risk factor for the development of neurodegenerative disease, yet the etiology of hypertension-driven neurodegeneration remains poorly understood.
Charith Perera +10 more
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Gut microbiota regulates blood-cerebrospinal fluid barrier function and Aβ pathology. [PDF]
EMBO J, 2023 Xie J +7 more
europepmc +2 more sources
The Potential Roles of Blood-Brain Barrier and Blood-Cerebrospinal Fluid Barrier in Maintaining Brain Manganese Homeostasis. [PDF]
Nutrients, 2021 McCabe SM, Zhao N.
europepmc +2 more sources
Cerebrospinal Fluid–Basic Concepts Review
Biomedicines, 2023 Cerebrospinal fluid plays a crucial role in protecting the central nervous system (CNS) by providing mechanical support, acting as a shock absorber, and transporting nutrients and waste products.
Natalia Czarniak +3 more
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The blood brain barrier and Lina Solomonovna Stern (Shtern)
Advances in Clinical Neuroscience & Rehabilitation, 2022 The blood–brain barrier (BBB) regulates the transport of molecules between the central nervous system (CNS) and blood. It consists of two components: the vascular endothelial cells forming so–called tight junctions, and the blood–cerebrospinal fluid ...
JMS Pearce
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