Results 21 to 30 of about 3,850,623 (241)

Advances in the Mechanism of Enriched Environment Improving Chronic Cerebral Hypoperfusion-induced Cognitive Impairment [PDF]

open access: yesZhongguo quanke yixue, 2022
Chronic cerebral hypoperfusion-induced cognitive impairment (CCHCI) is a cognitive deficit caused by cerebral cortex or subcortical infarction, white matter degeneration, blood-cerebrospinal fluid barrier, and hippocampal injury due to long-term ...
Huanhuan LIU, Jing GAO, Kaiqi SU, Xiaodong FENG
doaj   +1 more source

Increased blood-cerebrospinal fluid transfer of albumin in advanced Parkinson’s disease

open access: yesJournal of Neuroinflammation, 2012
Background Alterations in blood–brain barrier permeability have been proposed to represent a relevant factor contributing to Parkinson’s disease progression.
Pisani Valerio   +6 more
doaj   +1 more source

The embryonic blood-CSF barrier has molecular elements for specific glucose transport and for the general transport of molecules via transcellular routes. [PDF]

open access: yes, 2010
In vertebrates, early brain development takes place at the expanded anterior end of the neural tube, which is filled with embryonic cerebrospinal fluid (E-CSF).
Bueno i Torrens, David, 1965-   +3 more
core   +1 more source

"Compensated hyperosmolarity" of cerebrospinal fluid and the development of hydrocephalus [PDF]

open access: yes, 2013
Acute osmolar loading of cerebrospinal fluid within one lateral ventricle of dogs was examined as a cause of water extraction from the bloodstream and an increase in intracranial pressure.
Vladić, Anton   +4 more
core   +1 more source

Expansion of neopterin and beta2-microglobulin in cerebrospinal fluid reaches maximum levels early and late in the course of human immunodeficiency virus infection [PDF]

open access: yes, 1992
Inhaltsverzeichnis ...
Bogner, Johannes R.   +5 more
core   +1 more source

Importance of CSF-based Aβ clearance with age in humans increases with declining efficacy of blood-brain barrier/proteolytic pathways

open access: yesCommunications Biology, 2022
To understand if brain interstitial fluid/cerebrospinal fluid (ISF/CSF) exchange, CSF turnover, blood-brain barrier function or proteolysis were affected by aging or the presence of β amyloid plaques, Elbert et al.
Donald L. Elbert   +4 more
doaj   +1 more source

The Connected Steady State Model and the Interdependence of the CSF Proteome and CSF Flow Characteristics

open access: yesFrontiers in Neuroscience, 2017
Here we show that the hydrodynamic radii-dependent entry of blood proteins into cerebrospinal fluid (CSF) can best be modeled with a diffusional system of consecutive interdependent steady states between barrier-restricted molecular flux and bulk flow of
Fabian Metzger   +2 more
doaj   +1 more source

Case Report: Reduced CSF Orexin Levels in a Patient With Sepsis

open access: yesFrontiers in Neuroscience, 2021
Sepsis is a potentially lethal condition characterized by systemic inflammation and multiple organ failure, and sepsis-associated encephalopathy (SAE) is an independent risk factor for mortality in patients with sepsis. We previously reported that orexin
Yasuhiro Ogawa   +3 more
doaj   +1 more source

Prion protein in the cerebrospinal fluid of healthy and naturally scrapie-affected sheep [PDF]

open access: yes, 2006
The aim of this study was to characterize the cerebrospinal fluid (CSF) prion protein (PrP) of healthy and naturally scrapie-affected sheep. The soluble form of CSF PrPC immunoblotted with an anti-octarepeat and an anti-C terminus mAb showed two isoforms
Vé Ronique Gayrard   +13 more
core   +1 more source

Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier [PDF]

open access: yes, 2015
To clarify the significance of immunoglobulin G autoantibody specific for the astrocyte water channel aquaporin-4 in cerebrospinal fluid, aquaporin-4-immunoglobulin G from a neuromyelitis optica patient was administered intrathecally to naïve mice, and ...
Khorooshi, Reza; id_orcid   +4 more
core   +1 more source

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