Blood–brain and blood–cerebrospinal fluid barrier permeability in spontaneously hypertensive rats
Fluids and Barriers of the CNS, 2018 Background Hypertension is an important risk factor for cerebrovascular disease, including stroke and dementia. Both in humans and animal models of hypertension, neuropathological features such as brain atrophy and oedema have been reported.
Daphne M. P. Naessens +3 more
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Review of "The Blood-Cerebrospinal Fluid Barrier" by Wei Zheng and Adam Chodobski (editors)
Cerebrospinal Fluid Research, 2006 This multi-author volume on the blood-cerebrospinal fluid barrier summarizes past and current research in the areas of choroid plexus and cerebrospinal fluid in health and disease.
Jones Hazel C
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High Blood Pressure Effects on the Blood to Cerebrospinal Fluid Barrier and Cerebrospinal Fluid Protein Composition: A Two-Dimensional Electrophoresis Study in Spontaneously Hypertensive Rats [PDF]
International Journal of Hypertension, 2013 The aim of the present work is to analyze the cerebrospinal fluid proteomic profile, trying to find possible biomarkers of the effects of hypertension of the blood to CSF barrier disruption in the brain and their participation in the cholesterol and β ...
Ibrahim González-Marrero +8 more
doaj +2 more sources
Disruption of embryonic blood-CSF barrier in chick embryos reveals the actual importance of this barrier to control E-CSF composition and homeostasis in early brain development [PDF]
, 2013 In vertebrates, early brain development takes place at the expanded anterior end of the neural tube. After closure of the anterior neuropore, the brain wall forms a physiologically sealed cavity that encloses embryonic cerebrospinal fluid (E-CSF), a ...
Bueno i Torrens, David, 1965- +1 more
core +6 more sources
Cerebrospinal fluid supports viability and proliferation of cortical cells in vitro, mirroring in vivo development. [PDF]
, 2006 Background The central nervous system develops around a fluid filled compartment. Recently, attention has turned to the potential role of the fluid (cerebrospinal fluid, CSF) in the developmental process.
Mashayekhi, F. +3 more
core +5 more sources
SARS-CoV-2 infects epithelial cells of the blood-cerebrospinal fluid barrier rather than endothelial cells or pericytes of the blood-brain barrier. [PDF]
Fluids Barriers CNS, 2023 BACKGROUND As a consequence of SARS-CoV-2 infection various neurocognitive and neuropsychiatric symptoms can appear, which may persist for several months post infection.
Stüdle C +12 more
europepmc +3 more sources
Astroglia support, regulate and reinforce brain barriers
Neurobiology of Disease, 2023 Nervous system is segregated from the body by the complex system of barriers. The CNS is protected by (i) the blood–brain and blood-spinal cord barrier between the intracerebral and intraspinal blood vessels and the brain parenchyma; (ii) the arachnoid ...
Alexei Verkhratsky, Augustas Pivoriūnas
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Drug transport in brain
Fluids and Barriers of the CNS, 2011 The human brain has no lymphatic system, but produces over a half-liter each day of cerebrospinal fluid. The cerebrospinal fluid is secreted at the choroid plexus and occupies the cavities of the four ventricles, as well as the cranial and spinal sub ...
Pardridge William M
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Embryonic Blood-Cerebrospinal Fluid Barrier Formation and Function
Frontiers in Neuroscience, 2014 During embryonic development and adult life, brain cavities and ventricles are filled with cerebrospinal fluid (CSF). CSF has attracted interest as an active signaling medium that regulates brain development, homeostasis and disease.
David eBueno +3 more
doaj +1 more source
Ecotoxicology and Environmental Safety, 2023 Concerns regarding adverse effects of metal/metalloids exposure on brain development and neurological disorders among children are increasing. However, the transport patterns of metals/metalloids across the blood-cerebrospinal fluid barrier (BCSFB) need ...
Weixiang Wu +7 more
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