Embryonic Blood-Cerebrospinal Fluid Barrier Formation and Function [PDF]
Frontiers in Neuroscience, 2014 During embryonic development and adult life, brain cavities and ventricles are filled with cerebrospinal fluid (CSF). CSF has attracted interest as an active signaling medium that regulates brain development, homeostasis and disease.
David eBueno +3 more
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Blood–brain and blood–cerebrospinal fluid barrier permeability in spontaneously hypertensive rats
Fluids and Barriers of the CNS, 2018 Background Hypertension is an important risk factor for cerebrovascular disease, including stroke and dementia. Both in humans and animal models of hypertension, neuropathological features such as brain atrophy and oedema have been reported.
Daphne M. P. Naessens +3 more
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Review of "The Blood-Cerebrospinal Fluid Barrier" by Wei Zheng and Adam Chodobski (editors)
Cerebrospinal Fluid Research, 2006 This multi-author volume on the blood-cerebrospinal fluid barrier summarizes past and current research in the areas of choroid plexus and cerebrospinal fluid in health and disease.
Jones Hazel C
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The blood–brain and the blood–cerebrospinal fluid barriers: function and dysfunction [PDF]
Seminars in Immunopathology, 2009 The central nervous system (CNS) is tightly sealed from the changeable milieu of blood by the blood-brain barrier (BBB) and the blood-cerebrospinal fluid (CSF) barrier (BCSFB). While the BBB is considered to be localized at the level of the endothelial cells within CNS microvessels, the BCSFB is established by choroid plexus epithelial cells.
Engelhardt B, Sorokin L
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High Blood Pressure Effects on the Blood to Cerebrospinal Fluid Barrier and Cerebrospinal Fluid Protein Composition: A Two-Dimensional Electrophoresis Study in Spontaneously Hypertensive Rats [PDF]
International Journal of Hypertension, 2013 The aim of the present work is to analyze the cerebrospinal fluid proteomic profile, trying to find possible biomarkers of the effects of hypertension of the blood to CSF barrier disruption in the brain and their participation in the cholesterol and β ...
Ibrahim González-Marrero +8 more
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Drug transport in brain
Fluids and Barriers of the CNS, 2011 The human brain has no lymphatic system, but produces over a half-liter each day of cerebrospinal fluid. The cerebrospinal fluid is secreted at the choroid plexus and occupies the cavities of the four ventricles, as well as the cranial and spinal sub ...
Pardridge William M
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Effect of prolonged convulsions on the blood-cerebrospinal fluid barrier
American Journal of Physiology-Legacy Content, 1959 The effect of prolonged convulsions (induced by Metrazol or electroshock) on the blood-cerebrospinal fluid barrier of puppies was evaluated with the use of radioiodinated human serum albumin by measuring its rate of passage from the plasma into the cerebrospinal fluid. Albumin I131 was injected intravenously and convulsions were induced immediately by
M, LENDING, L B, SLOBODY, J, MESTERN
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Effect of Severe Hypoxia on Blood-Cerebrospinal Fluid Barrier
American Journal of Physiology-Legacy Content, 1957 The effect of severe hypoxia on the blood-cerebrospinal fluid barrier of dogs was evaluated from the rate of passage of radioiodinated human serum albumin from plasma to cisternal fluid. Hypoxia was induced by intratracheal administration of varying mixtures of O2 and N2 or by use of a Smith-Jones pressure chamber.
L B, SLOBODY +4 more
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Blood-Cerebrospinal Fluid Barrier Permeability in Alzheimer's Disease [PDF]
Journal of Alzheimer's Disease, 2011 The role of blood-cerebrospinal fluid barrier (BCB) dysfunction in Alzheimer's disease (AD) has been addressed but not yet established. We evaluated the BCB integrity in 179 samples of cerebrospinal fluid (CSF) retrospectively collected from AD patients and control cases using both CSF/serum albumin ratio (QAlb) and CSF secretory Ca2+-dependent ...
Sonia, Chalbot +6 more
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SARS-CoV-2 infects epithelial cells of the blood-cerebrospinal fluid barrier rather than endothelial cells or pericytes of the blood-brain barrier. [PDF]
Fluids Barriers CNS, 2023 BACKGROUND As a consequence of SARS-CoV-2 infection various neurocognitive and neuropsychiatric symptoms can appear, which may persist for several months post infection.
Stüdle C +12 more
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