Results 21 to 30 of about 80,920 (248)

Cerebrospinal fluid supports viability and proliferation of cortical cells in vitro, mirroring in vivo development. [PDF]

, 2006
Background The central nervous system develops around a fluid filled compartment. Recently, attention has turned to the potential role of the fluid (cerebrospinal fluid, CSF) in the developmental process.
Miyan Jaleel A, Miyan, Jaleel A.; id_orcid, P Jane Owen-Lynch, Zendah Mahjiub, Mashayekhi, F., Mahjiub Zendah, Zendah, Mahjiub, Jaleel A Miyan, Zendah, M., Mashayekhi Farhad, Farhad Mashayekhi, Owen-Lynch P Jane, Owen-Lynch, P. Jane, Miyan, J. A., Mashayekhi, Farhad   +14 more
core   +1 more source

Blood-cerebrospinal fluid barrier permeability of metals/metalloids and its determinants in pediatric patients

Ecotoxicology and Environmental Safety, 2023
Concerns regarding adverse effects of metal/metalloids exposure on brain development and neurological disorders among children are increasing. However, the transport patterns of metals/metalloids across the blood-cerebrospinal fluid barrier (BCSFB) need ...
Weixiang Wu, Xiaolin Ruan, Chunming Gu, Dan Luo, Jinfeng Ye, Fuqiang Diao, Lihong Wu, Mingyong Luo   +7 more
doaj   +1 more source

Prion protein in the cerebrospinal fluid of healthy and naturally scrapie-affected sheep [PDF]

, 2006
The aim of this study was to characterize the cerebrospinal fluid (CSF) prion protein (PrP) of healthy and naturally scrapie-affected sheep. The soluble form of CSF PrPC immunoblotted with an anti-octarepeat and an anti-C terminus mAb showed two isoforms
Vé Ronique Gayrard, Moudjou, Mohammed, Gayrard-Troy, Véronique, V., Pierre-Louis Toutain, Mohammed Moudjou, Chantal Imbs, Viguié, Catherine, Toutain, Pierre-Louis, Imbs, Chantal, Moudjou, Mohammed, M., Catherine Viguié, Nicole Picard-Hagen, Picard-Hagen, Nicole, Gayrard, Véronique   +13 more
core   +1 more source

Increased blood-cerebrospinal fluid transfer of albumin in advanced Parkinson’s disease

Journal of Neuroinflammation, 2012
Background Alterations in blood–brain barrier permeability have been proposed to represent a relevant factor contributing to Parkinson’s disease progression.
Pisani Valerio, Stefani Alessandro, Pierantozzi Mariangela, Natoli Silvia, Stanzione Paolo, Franciotta Diego, Pisani Antonio   +6 more
doaj   +1 more source

Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown [PDF]

, 2010
Background: An inducible release of soluble junctional adhesion molecule-A (sJAM-A) under pro-inflammatory conditions was described in cultured non-CNS endothelial cells (EC) and increased sJAM-A serum levels were found to indicate inflammation in non ...
Romero, Ignacio, Deiß Annika, Deiß, Annika, Buttmann, Mathias, Weksler Babette, Rieckmann, Peter, Ignacio Romero, Mathias Buttmann, Prochaska, Jürgen, Couraud, Pierre-Olivier, Jürgen Prochaska, Haarmann, Axel, Peter Rieckmann, Buttmann Mathias, Weksler, Babette, Axel Haarmann, Stoll, Guido, Najbauer, Joseph, Pierre-Olivier Couraud, Annika Deiss, Couraud Pierre-Olivier, Prochaska, Juergen, Stoll Guido, Guido Stoll, Förch, Christian, Romero Ignacio, Foerch, Christian, Prochaska Jürgen, Christian Foerch, Rieckmann Peter, Babette Weksler, Foerch Christian, Haarmann Axel   +32 more
core   +1 more source

Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier [PDF]

, 2015
To clarify the significance of immunoglobulin G autoantibody specific for the astrocyte water channel aquaporin-4 in cerebrospinal fluid, aquaporin-4-immunoglobulin G from a neuromyelitis optica patient was administered intrathecally to naïve mice, and ...
Khorooshi, Reza; id_orcid, Mørch, Marlene Thorsen, Owens, Trevor; id_orcid, Berg, Carsten Tue, Asgari, Nasrin   +4 more
core   +1 more source

Importance of CSF-based Aβ clearance with age in humans increases with declining efficacy of blood-brain barrier/proteolytic pathways

Communications Biology, 2022
To understand if brain interstitial fluid/cerebrospinal fluid (ISF/CSF) exchange, CSF turnover, blood-brain barrier function or proteolysis were affected by aging or the presence of β amyloid plaques, Elbert et al.
Donald L. Elbert, Bruce W. Patterson, Brendan P. Lucey, Tammie L. S. Benzinger, Randall J. Bateman   +4 more
doaj   +1 more source

Application of contrast-enhanced magnetic resonance imaging in the assessment of blood-cerebrospinal fluid barrier integrity

, 2021
VERHEGGEN, I.C.M., W. Freeze, J. de Jong, J. Jansen, A. Postma, M. van Boxtel, F. Verhey and W. Backes. The application of contrast-enhanced MRI in the assessment of blood-cerebrospinal fluid barrier integrity.
de Jong, Joost J A, Jansen, Jacobus F A, Verheggen, Inge C M, Backes, Walter H, Jansen, Jacobus F A; id_orcid, Postma, Alida A; id_orcid, van Boxtel, Martin P J, Verhey, Frans R J, Postma, Alida A, Freeze, Whitney M   +9 more
core   +2 more sources

Whole blood angiopoietin-1 and -2 levels discriminate cerebral and severe (non-cerebral) malaria from uncomplicated malaria [PDF]

, 2009
Background Severe and cerebral malaria are associated with endothelial activation. Angiopoietin-1 (ANG-1) and angiopoietin-2 (ANG-2) are major regulators of endothelial activation and integrity.
Liles W Conrad, Kain, Kevin C, Kevin C Kain, Kain Kevin C, Liles, W C, Conroy, Andrea L, Conroy Andrea L, Krudsood Srivicha, Erin I Lafferty, Srivicha Krudsood, Lafferty Erin I, Lovegrove, Fiona E, Lafferty, Erin I, Tangpukdee, Noppadon, Fiona E Lovegrove, W Conrad Liles, Tangpukdee Noppadon, Lovegrove Fiona E, Krudsood, Srivicha, Liles, W Conrad, Andrea L Conroy, Noppadon Tangpukdee   +21 more
core   +1 more source

Case Report: Reduced CSF Orexin Levels in a Patient With Sepsis

Frontiers in Neuroscience, 2021
Sepsis is a potentially lethal condition characterized by systemic inflammation and multiple organ failure, and sepsis-associated encephalopathy (SAE) is an independent risk factor for mortality in patients with sepsis. We previously reported that orexin
Yasuhiro Ogawa, Seioh Ezaki, Nobutake Shimojo, Satoru Kawano   +3 more
doaj   +1 more source