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Arquivos de Neuro-Psiquiatria, 1958 Whether electrolytes, colloids, vital dyes or other complex molecules, the rate of penetration of many plasma solutes into the extravascular fluids of the central nervous system is considerably slower than into the extra-vascular fluids of most other tissues.
Robert D. Tschirgi
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Dissecting gene expression at the blood-brain barrier [PDF]
Frontiers in Neuroscience, 2014 The availability of genome-wide expression data for the blood-brain barrier is an invaluable resource that has recently enabled the discovery of several genes and pathways involved in the development and maintenance of the blood-brain barrier ...
Melanie A Huntley +3 more
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Structure and function of the blood–brain barrier
Neurobiology of Disease, 2010 Neural signalling within the central nervous system (CNS) requires a highly controlled microenvironment. Cells at three key interfaces form barriers between the blood and the CNS: the blood–brain barrier (BBB), blood–CSF barrier and the arachnoid barrier.
N. Joan Abbott +4 more
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Metabolic syndrome and the immunologic affair with the blood-brain barrier [PDF]
Frontiers in Immunology, 2015 Epidemiological studies reveal an increased incidence of obesity worldwide, which is associated with increased prevalence and severity of cognitive disorders.
Claudio eMauro +3 more
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Vesicular Trafficking, a Mechanism Controlled by Cascade Activation of Rab Proteins: Focus on Rab27
Biology, 2023 Vesicular trafficking is essential for the cell to internalize useful proteins and soluble substances, for cell signaling or for the degradation of pathogenic elements such as bacteria or viruses.
Camille Menaceur +4 more
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Cells, 2023 Within the neurovascular unit, brain pericytes (BPs) are of major importance for the induction and maintenance of the properties of the blood-brain barrier (BBB) carried by the brain microvessel endothelial cells (ECs).
Camille Menaceur +9 more
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The blood–brain barrier: Structure, regulation and drug delivery
Signal Transduction and Targeted Therapy, 2023 Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous system (CNS) from toxins and pathogens in blood. However, the presence of BBB complicates the pharmacotherapy for CNS disorders as the most chemical drugs and ...
Di Wu +5 more
semanticscholar +1 more source
Appearance of claudin-5+ leukocyte subtypes in the blood and CNS during progression of EAE
Journal of Neuroinflammation, 2021 Background Tight junctions (TJs) are membrane specializations characteristic of barrier-forming membranes, which function to seal the aqueous pathway between endothelial cells or epithelial cells and, thereby, obstruct intercellular solute and cellular ...
Dylan Krajewski +4 more
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Real-time monitoring of human blood-brain barrier disruption [PDF]
, 2017 Chemotherapy aided by opening of the blood-brain barrier with intra-arterial infusion of hyperosmolar mannitol improves the outcome in primary central nervous system lymphoma.
Alahuhta, Seppo +15 more
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Stem Cell Research & Therapy, 2021 Background Cell-based therapeutic strategies have been proposed as an alternative for brain repair after stroke, but their clinical application has been hampered by potential adverse effects in the long term.
Rodrigo Azevedo Loiola +14 more
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