Results 11 to 20 of about 963,269 (378)
The blood-brain barrier. [PDF]
Cold Spring Harbor Perspectives in Biology, 2015 Blood vessels are critical to deliver oxygen and nutrients to all of the tissues and organs throughout the body. The blood vessels that vascularize the central nervous system (CNS) possess unique properties, termed the blood-brain barrier, which allow ...
R. Daneman, A. Prat
semanticscholar +4 more sources
Blood brain barrier opening is not just blood-brain barrier opening
Journal of Translational MedicineDeepa Sharma, Gregory J. Czarnota
doaj +3 more sources
Continuing Education in Anaesthesia Critical Care & Pain, 2011 The blood –brain barrier (BBB) is a highly regulated interface that separates the peripheral circulation and central nervous system (CNS). It functions primarily as a selective diffusion barrier at the level of the cerebral microvascular endothelium. The BBB is often defined structurally as specialized endothelial cells lining the intraluminal portion ...
Hari Krovvidi +2 more
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Blood-brain barrier transport kinetics of NOTA-modified proteins : the somatropin case [PDF]
, 2020 BACKGROUND: Chemical modifications such as PEG, polyamine and radiolabeling on proteins can alter their pharmacokinetic behaviour and their blood-brain barrier (BBB) transport characteristics. NOTA, i.e. 1,4,7-triazacyclononane-1,4,7-triacetic acid, is a
Bracke, Nathalie +7 more
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Between two storms, vasoactive peptides or bradykinin underlie severity of COVID‐19?
Physiological Reports, 2021 Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), continues to be a world‐wide pandemic with overwhelming socioeconomic impact.
Vardan T. Karamyan
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A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrity
Fluids and Barriers of the CNS, 2020 The blood–brain barrier is playing a critical role in controlling the influx and efflux of biological substances essential for the brain’s metabolic activity as well as neuronal function.
Hossam Kadry, Behnam Noorani, L. Cucullo
semanticscholar +1 more source
Neuroinflammation, Stroke, Blood-Brain Barrier Dysfunction, and Imaging Modalities.
Stroke, 2022 Maintaining blood-brain barrier (BBB) integrity is crucial for the homeostasis of the central nervous system. Structurally comprising the BBB, brain endothelial cells interact with pericytes, astrocytes, neurons, microglia, and perivascular macrophages ...
E. Candelario-Jalil +2 more
semanticscholar +1 more source
Mucopolysaccharidoses and the blood–brain barrier
Fluids and Barriers of the CNS, 2022 AbstractMucopolysaccharidoses comprise a set of genetic diseases marked by an enzymatic dysfunction in the degradation of glycosaminoglycans in lysosomes. There are eight clinically distinct types of mucopolysaccharidosis, some with various subtypes, based on which lysosomal enzyme is deficient and symptom severity.
Sahin, Onur +4 more
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