Results 31 to 40 of about 957,746 (360)
Blood vessels are critical to deliver oxygen and nutrients to all of the tissues and organs throughout the body. The blood vessels that vascularize the central nervous system (CNS) possess unique properties, termed the blood-brain barrier, which allow ...
R. Daneman, A. Prat
semanticscholar +1 more source
Activation of Wnt/β-catenin pathway mitigates blood–brain barrier dysfunction in Alzheimer’s disease
Alzheimer’s disease is a neurodegenerative disorder that causes age-dependent neurological and cognitive declines. The treatments for Alzheimer’s disease pose a significant challenge, because the mechanisms of disease are not being fully understood ...
Qi Wang+13 more
semanticscholar +1 more source
Quantum over-barrier reflection effects manifested in the photodetachment cross sections [PDF]
Photodetachment of H$^-$ near a potential barrier is studied. A new formula is presented for the cross sections induced by a barrier. The new formula describes two quantum effects near barrier tops. For energies near and above barrier tops, the quantum over-barrier reflection effects are included and the induced oscillations in the cross sections are ...
arxiv +1 more source
Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers
Extracellular vesicles (EVs) are heterogeneous, nano-sized vesicles that are shed into the blood and other body fluids, which disperse a variety of bioactive molecules (e.g., protein, mRNA, miRNA, DNA and lipids) to cellular targets over long and short ...
Servio H. Ramirez+3 more
doaj +1 more source
Multi-step Reflection Principle and Barrier Options [PDF]
This paper examines a class of barrier options-multi-step barrier options, which can have any finite number of barriers of any level. We obtain a general, explicit expression of option prices of this type under the Black-Scholes model. Multi-step barrier options are not only useful in that they can handle barriers of different levels and time steps ...
arxiv
Transferrin Receptor Mediated Brain Uptake During Ischemia and Reperfusion
Purpose. Drug delivery by transferrin receptor-mediated transport at the blood-brain barrier has shown beneficial effects in animal models of stroke, but it is unclear whether receptor mediated uptake remains functional in the ischemic tissue.
Jiukuan Hao, Ulrich Bickel
doaj +1 more source
Distributed Control Strategy for Layered Barrier Coverage of Multi-Agent Systems in Uncertain Environments [PDF]
This paper presents a distributed multi-layer ring barrier coverage algorithm. In order to achieve single-layer ring barrier coverage, a distributed single-layer ring barrier coverage algorithm that maximises the probability of monitoring is proposed.
arxiv
Reflected backward stochastic differential equations with optional barriers: monotone approximation [PDF]
In this short note we consider RBSDE with Lipschitz drivers and barrier processes that are optional and right upper semicontinuous. We treat the case when the barrier can be represented as a decreasing limit of cadlag barriers. We combine well known existence results for cadlag barriers with comparison arguments for the control process to construct ...
arxiv
Adiabatic Heavy Ion Fusion Potentials for Fusion at Deep Sub-barrier Energies [PDF]
The fusion cross sections from well above barrier to extreme sub-barrier energies have been analysed using the energy (E) and angular momentum (L) dependent barrier penetration model ({\small{ELDBPM}}). From this analysis, the adiabatic limits of fusion barriers have been determined for a wide range of heavy ion systems.
arxiv +1 more source
Lymphodepletion chemotherapy followed by infusion of CD19-targeted chimeric antigen receptor-modified T (CAR-T) cells can be complicated by neurologic adverse events (AE) in patients with refractory B-cell malignancies.
J. Gust+23 more
semanticscholar +1 more source