Results 31 to 40 of about 957,746 (360)

The blood-brain barrier.

open access: yesCold Spring Harbor Perspectives in Biology, 2015
Blood vessels are critical to deliver oxygen and nutrients to all of the tissues and organs throughout the body. The blood vessels that vascularize the central nervous system (CNS) possess unique properties, termed the blood-brain barrier, which allow ...
R. Daneman, A. Prat
semanticscholar   +1 more source

Activation of Wnt/β-catenin pathway mitigates blood–brain barrier dysfunction in Alzheimer’s disease

open access: yesBrain : a journal of neurology, 2022
Alzheimer’s disease is a neurodegenerative disorder that causes age-dependent neurological and cognitive declines. The treatments for Alzheimer’s disease pose a significant challenge, because the mechanisms of disease are not being fully understood ...
Qi Wang   +13 more
semanticscholar   +1 more source

Quantum over-barrier reflection effects manifested in the photodetachment cross sections [PDF]

open access: yesJ. Phys. B: At. Mol. Opt. Phys. 45 175003 (2012), 2012
Photodetachment of H$^-$ near a potential barrier is studied. A new formula is presented for the cross sections induced by a barrier. The new formula describes two quantum effects near barrier tops. For energies near and above barrier tops, the quantum over-barrier reflection effects are included and the induced oscillations in the cross sections are ...
arxiv   +1 more source

Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers

open access: yesFluids and Barriers of the CNS, 2018
Extracellular vesicles (EVs) are heterogeneous, nano-sized vesicles that are shed into the blood and other body fluids, which disperse a variety of bioactive molecules (e.g., protein, mRNA, miRNA, DNA and lipids) to cellular targets over long and short ...
Servio H. Ramirez   +3 more
doaj   +1 more source

Multi-step Reflection Principle and Barrier Options [PDF]

open access: yesarXiv, 2021
This paper examines a class of barrier options-multi-step barrier options, which can have any finite number of barriers of any level. We obtain a general, explicit expression of option prices of this type under the Black-Scholes model. Multi-step barrier options are not only useful in that they can handle barriers of different levels and time steps ...
arxiv  

Transferrin Receptor Mediated Brain Uptake During Ischemia and Reperfusion

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2013
Purpose. Drug delivery by transferrin receptor-mediated transport at the blood-brain barrier has shown beneficial effects in animal models of stroke, but it is unclear whether receptor mediated uptake remains functional in the ischemic tissue.
Jiukuan Hao, Ulrich Bickel
doaj   +1 more source

Distributed Control Strategy for Layered Barrier Coverage of Multi-Agent Systems in Uncertain Environments [PDF]

open access: yesarXiv, 2023
This paper presents a distributed multi-layer ring barrier coverage algorithm. In order to achieve single-layer ring barrier coverage, a distributed single-layer ring barrier coverage algorithm that maximises the probability of monitoring is proposed.
arxiv  

Reflected backward stochastic differential equations with optional barriers: monotone approximation [PDF]

open access: yesarXiv, 2021
In this short note we consider RBSDE with Lipschitz drivers and barrier processes that are optional and right upper semicontinuous. We treat the case when the barrier can be represented as a decreasing limit of cadlag barriers. We combine well known existence results for cadlag barriers with comparison arguments for the control process to construct ...
arxiv  

Adiabatic Heavy Ion Fusion Potentials for Fusion at Deep Sub-barrier Energies [PDF]

open access: yesPramana64:47-54,2005, 2003
The fusion cross sections from well above barrier to extreme sub-barrier energies have been analysed using the energy (E) and angular momentum (L) dependent barrier penetration model ({\small{ELDBPM}}). From this analysis, the adiabatic limits of fusion barriers have been determined for a wide range of heavy ion systems.
arxiv   +1 more source

Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells.

open access: yesCancer Discovery, 2017
Lymphodepletion chemotherapy followed by infusion of CD19-targeted chimeric antigen receptor-modified T (CAR-T) cells can be complicated by neurologic adverse events (AE) in patients with refractory B-cell malignancies.
J. Gust   +23 more
semanticscholar   +1 more source

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