Results 61 to 70 of about 957,746 (360)

Dual microglia effects on blood brain barrier permeability induced by systemic inflammation

open access: yesNature Communications, 2019
Microglia survey brain parenchyma, responding to injury and infections. Microglia also respond to systemic disease, but the role of blood–brain barrier (BBB) integrity in this process remains unclear.
Koichiro Haruwaka   +12 more
semanticscholar   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Peripheral inflammation and blood–brain barrier disruption: effects and mechanisms

open access: yesCNS Neuroscience & Therapeutics, 2020
The blood–brain barrier (BBB) is an important physiological barrier that separates the central nervous system (CNS) from the peripheral circulation, which contains inflammatory mediators and immune cells. The BBB regulates cellular and molecular exchange
Xiaowen Huang   +2 more
semanticscholar   +1 more source

Age-related changes in blood-brain barrier integrity in C57BL/6J mice [PDF]

open access: yes, 2013
The blood-brain barrier (BBB) is formed by the endothelial cells of the brain microvasculature, which control the molecular traffic between the blood and brain to maintain the neural ...
Romero, I. A., Saffrey, M. J., Wang, C.
core  

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Composite fermions traversing a potential barrier [PDF]

open access: yes, 1995
Using a composite fermion picture, we study the lateral transport between two two-dimensional electron gases, at filling factor 1/2, separated by a potential barrier. In the mean field approximation, composite fermions far from the barrier do not feel a magnetic field while in the barrier region the effective magnetic field is different from zero. This
arxiv   +1 more source

Targeting and Crossing the Blood-Brain Barrier with Extracellular Vesicles

open access: yesCells, 2020
The blood–brain barrier (BBB) is one of the most complex and selective barriers in the human organism. Its role is to protect the brain and preserve the homeostasis of the central nervous system (CNS).
J. Saint-Pol   +4 more
semanticscholar   +1 more source

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

Tunneling effect of fermions in silicene through potential barrier [PDF]

open access: yesarXiv, 2022
The influence of a rectangular potential barrier on the quantum transport of fermions in silicene is explored. Specifically, analytical solutions are presented to derive transmission and reflection probabilities together with conductance. It is shown that the transmission is highly sensitive to both the barrier height and incident energy.
arxiv  

Blood-Brain Barrier Overview: Structural and Functional Correlation

open access: yesJournal of Neural Transplantation and Plasticity, 2021
The blood-brain barrier (BBB) is a semipermeable and extremely selective system in the central nervous system of most vertebrates, that separates blood from the brain's extracellular fluid.
Abeer Alahmari
semanticscholar   +1 more source

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