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PLATELET TURNOVER AND ATHEROTHROMBOSIS
Platelets play an important role in initiating atherothrombosis, i.e. the formation of blood clots inside a blood vessel at areas of atherosclerotic vascular injury.
A. V. MAZUROV
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Therapeutic use of red blood cells and platelets derived from human cord blood stem cells
Red blood cells (RBCs) and platelets derived from stem cells are possible solutions to the increasing demand for blood transfusion. Based on the availability of stem cells, their relatively defined differentiation mechanisms, and the massive exploration ...
Xiaoyan Xie +4 more
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Shiga toxin and lipopolysaccharide induce platelet-leukocyte aggregates and tissue factor release, a thrombotic mechanism in hemolytic uremic syndrome. [PDF]
BACKGROUND:Aggregates formed between leukocytes and platelets in the circulation lead to release of tissue factor (TF)-bearing microparticles contributing to a prothrombotic state.
Anne-lie Ståhl +4 more
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Platelet Function in Platelet Concentrates and in Whole Blood [PDF]
Platelet function was studied in CPD whole blood stored at 4°C for one and three days and in platelet concentrates stored at room temperature for the same periods of time. Comparisons were made of platelet shape, nucleotide content, β-thromboglobulin (βTG) liberated during storage, and platelet aggregation in response to ADP, collagen, sodium ...
S E, Rodgers, J V, Lloyd, W J, Russell
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In vitro-derived platelets: the challenges we will have to face to assess quality and safety
Platelet transfusions are given to patients in hospital who have a low blood platelet count (thrombocytopenia) either because of major bleeding (following trauma or surgery) or because the bone marrow production of platelets is impaired often due to ...
S. Mookerjee +3 more
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[Objective] To retrospectively compare the impact of different intraoperative transfusion strategies for platelets and cryoprecipitate on perioperative blood usage and clinical outcomes in patients undergoing orthotopic heart transplant (OHT), thereby ...
ZHANG Rui +5 more
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Erythrocytes morphology and hemorheology in severe bacterial infection [PDF]
BACKGROUND Severe bacterial infections initiate inadequate inflammation that leads to disseminated intravascular coagulation and death. OBJECTIVES To evaluate the influence of bacterial infection on blood viscosity and red blood cells (RBCs ...
Ayrles FB Silva +7 more
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Platelet Separation From Whole Blood in an Aqueous Two-Phase System With Water-Soluble Polymers
.: Platelet-rich plasma (PRP) stimulates tissue healing and centrifugation is the only method for PRP preparation. The purpose of the present study was to develop a method to separate platelets without centrifugation.
Sumida Emi +3 more
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An acoustofluidic device for the automated separation of platelet-reduced plasma from whole blood
Separating plasma from whole blood is an important sample processing technique required for fundamental biomedical research, medical diagnostics, and therapeutic applications.
Zhehan Ma +11 more
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Purity, limited platelet activation, and preservation of platelet function are important stakes of preparation of platelet concentrates (PC) for clinical use.
Pierre Bohec +6 more
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