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Blood platelets: Circulating mirrors of neurons? [PDF]
Research and Practice in Thrombosis and Haemostasis, 2019 Blood platelets and resident neurons are fundamentally different cells, with peculiar features in embryological origin, function, and localization. However, they share common characteristics in subcellular organization and in protein composition.1 One of
Ilaria Canobbio
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The aggregation of blood platelets [PDF]
The Journal of Physiology, 1963 Inthe circulating bloodtheplatelets are normally carried along separately from each other and there is no evidence that they adhere to normal vascular endothelium.
M. J. Cross, G. V. R. Born
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Blood Platelets as an Important but Underrated Circulating Source of TGFβ. [PDF]
Int J Mol Sci, 2021 When treating diseases related primarily to tissue remodeling and fibrosis, it is desirable to regulate TGFβ concentration and modulate its biological effects. The highest cellular concentrations of TGFβ are found in platelets, with about 40% of all TGFβ
Karolczak K, Watala C.
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THE HISTOGENESIS OF BLOOD PLATELETS [PDF]
Journal of Experimental Medicine, 1913 1. Under normal circumstances blood platelets are largely derived from the megakaryocyte of the blood-forming organs. 2. The transitional leucocyte, representing a persistent form of the embryonic premegakaryocyte, is a circulating homologue of the megakaryocyte and probably plays some part in normal platelet formation. 3.
W. Brown
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Pro-Thrombotic Activity of Blood Platelets in Multiple Sclerosis. [PDF]
Cells, 2019 The available data, including experimental studies, clearly indicate an excessive intravascular activation of circulating platelets in multiple sclerosis (MS) and their hyper-responsiveness to a variety of physiological activators. Platelet activation is
Saluk-Bijak J, Dziedzic A, Bijak M.
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THE BLOOD PLATELETS IN HEMOPHILIA [PDF]
Archives of Internal Medicine, 1916 Hemophilia on account of its striking nature was early recognized as a clinical entity, and has been the subject of many observations. Many theories as to its causation have been advanced. With the development of methods for the study of the blood it has been possible to discard most of the theories concerning this interesting disease.
Roger I. Lee, George R. Minot
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THE RATE OF REGENERATION OF BLOOD PLATELETS [PDF]
Journal of Experimental Medicine, 1911 By repeatedly withdrawing, defibrinating, and reinjecting blood, the platelet count in dogs can be reduced to an extremely low level. When the reduction in platelets and fibrinogen has been carried to an extreme degree the animals display a marked tendency to bleed.
I}pt Nat +2 more
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Adenosine and blood platelets [PDF]
Purinergic Signalling, 2011 Adenosine is an important regulatory metabolite and an inhibitor of platelet activation. Adenosine released from different cells or generated through the activity of cell-surface ectoenzymes exerts its effects through the binding of four different G-protein-coupled adenosine receptors.
Katya Ravid, Hillary Johnston-Cox
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Regulating billions of blood platelets: glycans and beyond.
Blood, 2015 The human body produces and removes 10(11) platelets daily to maintain a normal steady state platelet count. Platelet production must be regulated to avoid spontaneous bleeding or arterial occlusion and organ damage.
Grozovsky R +3 more
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Folia Histochemica et Cytobiologica, 2011 Ulcerative colitis (colitis ulcerosa) is a non-specific inflammatory bowel disease of unknown etiology. Thesymptoms which are observed in the course of ulcerative colitis are: an increase in the number of leukocytes andblood platelets, an increase in the
Beata Polińska +2 more
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