Blood platelets: Circulating mirrors of neurons? [PDF]
Research and Practice in Thrombosis and Haemostasis, 2019 Blood platelets and resident neurons are fundamentally different cells, with peculiar features in embryological origin, function, and localization. However, they share common characteristics in subcellular organization and in protein composition.1 One of
Ilaria Canobbio
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Blood Platelets as an Important but Underrated Circulating Source of TGFβ. [PDF]
Int J Mol Sci, 2021 When treating diseases related primarily to tissue remodeling and fibrosis, it is desirable to regulate TGFβ concentration and modulate its biological effects. The highest cellular concentrations of TGFβ are found in platelets, with about 40% of all TGFβ
Karolczak K, Watala C.
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Relationship between the Increased Haemostatic Properties of Blood Platelets and Oxidative Stress Level in Multiple Sclerosis Patients with the Secondary Progressive Stage [PDF]
Oxidative Medicine and Cellular Longevity, 2015 Multiple sclerosis (MS) is the autoimmune disease of the central nervous system with complex pathogenesis, different clinical courses and recurrent neurological relapses and/or progression. Despite various scientific papers that focused on early stage of
Bijak, Michal +5 more
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Pro-Thrombotic Activity of Blood Platelets in Multiple Sclerosis. [PDF]
Cells, 2019 The available data, including experimental studies, clearly indicate an excessive intravascular activation of circulating platelets in multiple sclerosis (MS) and their hyper-responsiveness to a variety of physiological activators. Platelet activation is
Saluk-Bijak J, Dziedzic A, Bijak M.
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Obstructive Sleep Apnea: From Intermittent Hypoxia to Cardiovascular Complications via Blood Platelets. [PDF]
Front Neurol, 2018 Obstructive sleep apnea is a chronic condition characterized by recurrent episodes of apneas or hypopneas during sleep leading to intermittent hypoxemia and arousals.
Gabryelska A +3 more
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Blood platelets in the progression of Alzheimer's disease. [PDF]
PLoS One, 2014 Alzheimer’s disease (AD) is characterized by neurotoxic amyloid-ß plaque formation in brain parenchyma and cerebral blood vessels known as cerebral amyloid angiopathy (CAA).
Gowert NS +16 more
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Folia Histochemica et Cytobiologica, 2011 Ulcerative colitis (colitis ulcerosa) is a non-specific inflammatory bowel disease of unknown etiology. Thesymptoms which are observed in the course of ulcerative colitis are: an increase in the number of leukocytes andblood platelets, an increase in the
Beata Polińska +2 more
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The role of platelets in the blood-brain barrier during brain pathology [PDF]
Frontiers in Cellular NeurosciencePlatelets play critical roles in maintaining hemostasis. The blood brain barrier (BBB), a significant physical and metabolic barrier, helps maintain physiological stability by limiting transportations between the blood and neural tissues.
Weifeng Lv, Xiaofan Jiang, Yanyu Zhang
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Flavonolignans inhibit the arachidonic acid pathway in blood platelets. [PDF]
BMC Complement Altern Med, 2017 Bijak M, Saluk-Bijak J.
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Therapeutic potential of adult platelets and cord blood platelets in future clinical directions
Journal of Medical and Scientific Research, 2023 Platelet rich plasma (PRP) is currently obtaining a natural concentration of autologous growth factors, and is used in different medical conditions. This review is aimed to establish several treatment options using adult PRP and scope of the therapeutic ...
Bezawada SR, Velluri V, Darapuneni RC
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