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Blood platelets: Circulating mirrors of neurons? [PDF]
Research and Practice in Thrombosis and Haemostasis, 2019 Blood platelets and resident neurons are fundamentally different cells, with peculiar features in embryological origin, function, and localization. However, they share common characteristics in subcellular organization and in protein composition.1 One of
Ilaria Canobbio
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The aggregation of blood platelets [PDF]
The Journal of Physiology, 1963 M. J. Cross, G. V. R. Born
semanticscholar +5 more sources
Blood Platelets as an Important but Underrated Circulating Source of TGFβ. [PDF]
Int J Mol Sci, 2021 When treating diseases related primarily to tissue remodeling and fibrosis, it is desirable to regulate TGFβ concentration and modulate its biological effects. The highest cellular concentrations of TGFβ are found in platelets, with about 40% of all TGFβ
Karolczak K, Watala C.
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Relationship between the Increased Haemostatic Properties of Blood Platelets and Oxidative Stress Level in Multiple Sclerosis Patients with the Secondary Progressive Stage [PDF]
Oxidative Medicine and Cellular Longevity, 2015 Multiple sclerosis (MS) is the autoimmune disease of the central nervous system with complex pathogenesis, different clinical courses and recurrent neurological relapses and/or progression. Despite various scientific papers that focused on early stage of
Bijak, Michal +5 more
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Pro-Thrombotic Activity of Blood Platelets in Multiple Sclerosis. [PDF]
Cells, 2019 The available data, including experimental studies, clearly indicate an excessive intravascular activation of circulating platelets in multiple sclerosis (MS) and their hyper-responsiveness to a variety of physiological activators. Platelet activation is
Saluk-Bijak J, Dziedzic A, Bijak M.
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THE HISTOGENESIS OF BLOOD PLATELETS [PDF]
Journal of Experimental Medicine, 1913 1. Under normal circumstances blood platelets are largely derived from the megakaryocyte of the blood-forming organs. 2. The transitional leucocyte, representing a persistent form of the embryonic premegakaryocyte, is a circulating homologue of the megakaryocyte and probably plays some part in normal platelet formation. 3.
W. Brown
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THE BLOOD PLATELETS IN HEMOPHILIA [PDF]
Archives of Internal Medicine, 1916 Hemophilia on account of its striking nature was early recognized as a clinical entity, and has been the subject of many observations. Many theories as to its causation have been advanced. With the development of methods for the study of the blood it has been possible to discard most of the theories concerning this interesting disease.
Roger I. Lee, George R. Minot
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Obstructive Sleep Apnea: From Intermittent Hypoxia to Cardiovascular Complications via Blood Platelets. [PDF]
Front Neurol, 2018 Obstructive sleep apnea is a chronic condition characterized by recurrent episodes of apneas or hypopneas during sleep leading to intermittent hypoxemia and arousals.
Gabryelska A +3 more
europepmc +2 more sources
Blood platelets and sepsis pathophysiology: A new therapeutic prospect in critically [corrected] ill patients? [PDF]
Ann Intensive Care, 2017 Beyond haemostasis, platelets have emerged as versatile effectors of the immune response. The contribution of platelets in inflammation, tissue integrity and defence against infections has considerably widened the spectrum of their role in health and ...
Dewitte A +6 more
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THE RATE OF REGENERATION OF BLOOD PLATELETS [PDF]
Journal of Experimental Medicine, 1911 By repeatedly withdrawing, defibrinating, and reinjecting blood, the platelet count in dogs can be reduced to an extremely low level. When the reduction in platelets and fibrinogen has been carried to an extreme degree the animals display a marked tendency to bleed.
I}pt Nat +2 more
openaire +7 more sources