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THE RATE OF REGENERATION OF BLOOD PLATELETS [PDF]
By repeatedly withdrawing, defibrinating, and reinjecting blood, the platelet count in dogs can be reduced to an extremely low level. When the reduction in platelets and fibrinogen has been carried to an extreme degree the animals display a marked tendency to bleed.
I}pt Nat+2 more
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In vitro-derived platelets: the challenges we will have to face to assess quality and safety [PDF]
Platelet transfusions are given to patients in hospital who have a low blood platelet count (thrombocytopenia) either because of major bleeding (following trauma or surgery) or because the bone marrow production of platelets is impaired often due to ...
S. Mookerjee+3 more
doaj +2 more sources
Blood platelets in the progression of Alzheimer's disease. [PDF]
Alzheimer’s disease (AD) is characterized by neurotoxic amyloid-ß plaque formation in brain parenchyma and cerebral blood vessels known as cerebral amyloid angiopathy (CAA).
Gowert NS+16 more
europepmc +2 more sources
Adenosine and blood platelets [PDF]
Adenosine is an important regulatory metabolite and an inhibitor of platelet activation. Adenosine released from different cells or generated through the activity of cell-surface ectoenzymes exerts its effects through the binding of four different G-protein-coupled adenosine receptors.
Katya Ravid, Hillary Johnston-Cox
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THE PHYSIOLOGY OF BLOOD PLATELETS [PDF]
Since the publication of the proceedings of the Henry Ford Hospital Symposium on Blood Platelets in 1960 much has been accomplished in research on various aspects of platelet structure and function. Marcus and Zucker have drawn from their extensive experience, culled the current literature, and summarized succinctly and expertly many facets of platelet
John O’Brien
+8 more sources
Regulating billions of blood platelets: glycans and beyond.
The human body produces and removes 10(11) platelets daily to maintain a normal steady state platelet count. Platelet production must be regulated to avoid spontaneous bleeding or arterial occlusion and organ damage.
Grozovsky R+3 more
europepmc +2 more sources
Shiga toxin and lipopolysaccharide induce platelet-leukocyte aggregates and tissue factor release, a thrombotic mechanism in hemolytic uremic syndrome. [PDF]
BACKGROUND:Aggregates formed between leukocytes and platelets in the circulation lead to release of tissue factor (TF)-bearing microparticles contributing to a prothrombotic state.
Anne-lie Ståhl+4 more
doaj +5 more sources
Leukocyte- and platelet-derived microvesicle interactions following in vitro and in vivo activation of toll-like receptor 4 by lipopolysaccharide. [PDF]
BACKGROUND: Pro-coagulant membrane microvesicles (MV) derived from platelets and leukocytes are shed into the circulation following receptor-mediated activation, cell-cell interaction, and apoptosis. Platelets are sentinel markers of toll-like receptor 4
Jing Xiong+4 more
doaj +5 more sources
The histogenesis of the blood platelets
From Publications of the Massachusetts General Hospital, Boston. Vol. III. No. 1 1910. ; From the Journal of Morphology. Vol. 21 no. 2 July, 1910. 21. 263-278. pl. 1, 2. ; Mode of access: Internet.
J. H. Wright
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