Results 21 to 30 of about 479,353 (206)

Dose-dependent effect of canine lyophilized platelet on an in vitro hemodilution model

open access: yesBMC Veterinary Research, 2023
The transfusion of stored platelets has emerged as an efficient method for treating dogs with thrombocytopenia. However, the availability of fresh platelets is limited in veterinary medicine due to demanding storage conditions. Lyophilized platelets have
Mu-Young Kim, Hyun-Jung Han
doaj   +1 more source

Relationship between the Increased Haemostatic Properties of Blood Platelets and Oxidative Stress Level in Multiple Sclerosis Patients with the Secondary Progressive Stage [PDF]

open access: yes, 2015
Multiple sclerosis (MS) is the autoimmune disease of the central nervous system with complex pathogenesis, different clinical courses and recurrent neurological relapses and/or progression. Despite various scientific papers that focused on early stage of
Bijak, Michal   +5 more
core   +3 more sources

Blood platelet kinetics and platelet transfusion [PDF]

open access: yesJournal of Clinical Investigation, 2013
The discovery of citrate anticoagulant in the 1920s and the development of plastic packs for blood collection in the 1960s laid the groundwork for platelet transfusion therapy on a scale not previously possible. A major limitation, however, was the finding that platelet concentrates prepared from blood anticoagulated with citrate were unsuitable for ...
openaire   +2 more sources

EDTA stabilizes the concentration of platelet-derived extracellular vesicles during blood collection and handling

open access: yesPlatelets, 2022
Citrate is the recommended anticoagulant for studies on plasma extracellular vesicles (EVs). Because citrate incompletely blocks platelet activation and the release of platelet-derived EVs, we compared EDTA and citrate in that regard.
Naomi C. Buntsma   +5 more
doaj   +1 more source

Intraoperative blood transfusions in highly alloimmunized patients undergoing orthotopic liver transplantation. [PDF]

open access: yes, 1989
Intraoperative blood requirements were analyzed in patients undergoing primary orthotopic liver transplantation and divided into two groups on the basis of panel reactive antibody of pretransplant serum measured by lymphocytotoxicity testing.
Duquesnoy, RJ   +5 more
core   +1 more source

Original Effective, Safe Technique of Obtaining Platelet Rich Plasma by Centrifugation of the Blood Plasma in Modified Syringe Containers [PDF]

open access: yes, 2019
The aim: to develop, substantiate an effective and safe technology for producing PRP (platelet rich plasma). To quantify the substrate based on the recommended centrifugation protocols.Materials and methods: the effectiveness of the original harvesting ...
Atanasov, D. (Dmitro)   +1 more
core   +3 more sources

Role of Thrombocytic-Vascular Hemostasis in the Development of Pulmonary Complications in Severe Brain Injury

open access: yesОбщая реаниматология, 2006
The purpose of the study was to define a role of thrombocytic-vascular hemostasis in the development of pulmonary complications in severe brain injury. Forty-six patients with severe brain injury were studied over time.
Yu. A. Churlyaev, L. Yu. Redkokasha
doaj   +1 more source

Platelet-leukocyte interactions: immunoregulatory role and pathophysiological relevance

open access: yesМедицинская иммунология, 2022
Blood platelets are the central players in thrombosis and blood coagulation. Moreover, they also exhibit immunoregulatory properties and bridge hemostasis and immunity.
O. V. Pavlov   +3 more
doaj   +1 more source

Quantitative structural mechanobiology of platelet-driven blood clot contraction. [PDF]

open access: yes, 2017
Blood clot contraction plays an important role in prevention of bleeding and in thrombotic disorders. Here, we unveil and quantify the structural mechanisms of clot contraction at the level of single platelets.
Alber, Mark S   +3 more
core   +2 more sources

Platelet number in different anticoagulants as a diagnostic biomarker for increased intestinal permeability

open access: yesPlatelets, 2020
The main pathological process associated to increased intestinal permeability is the translocation of toxic products, predominantly endotoxins/lipopolysaccharide (LPS), from the intestinal tract into the microcirculation.
Mercedes Lopez, Goetz Nowak
doaj   +1 more source

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