Immersed boundary simulations of cell-cell interactions in whole blood [PDF]
We present a new method for the geometric reconstruction of elastic surfaces simulated by the immersed boundary method with the goal of simulating the motion and interactions of cells in whole blood. Our method uses parameter-free radial basis functions for high-order meshless parametric reconstruction of point clouds and the elastic force computations
arxiv +1 more source
Although platelets and the coagulation factors are components of the blood system, they become part of and contribute to the tumor microenvironment (TME) not only within a solid tumor mass, but also within a hematogenous micrometastasis on its way ...
Wolfgang M. J. Obermann+2 more
doaj +1 more source
Presence and activity of Fibrinogen like protein 2 in platelets.
BackgroundFibrinogen-like protein 2 (FGL2) is a serine protease capable of converting prothrombin into thrombin (i.e., prothrombinase-like activity) while bypassing the classic coagulation cascade.
Izhack Cherny+5 more
doaj +1 more source
Microfluidic flow chambers using reconstituted blood to model hemostasis and platelet transfusion in vitro [PDF]
Blood platelets prepared for transfusion gradually lose hemostatic function during storage. Platelet function can be investigated using a variety of (indirect) in vitro experiments, but none of these is as comprehensive as microfluidic flow chambers.
Compernolle, Veerle+4 more
core +2 more sources
Platelet kinetics in the pulmonary microcirculation in vivo assessed by intravital microscopy [PDF]
Growing evidence supports the substantial pathophysiological impact of platelets on the development of acute lung injury. Methods for studying these cellular mechanisms in vivo are not present yet.
Eichhorn, M. E.+3 more
core +1 more source
BLOOD-PLATELETS AND TUBERCULOSIS [PDF]
So little is known concerning blood-platelets, and so little interest has been taken in them, that their description by Adami and Nichols 1 is almost fully quoted. If only because they play so important a part in the process of thrombosis it is necessary to have a clear understanding regarding the blood-platelets, or, more accurately, regarding what ...
Gerald B. Webb+2 more
openaire +2 more sources
Perbedaan Hitung Jumlah Trombosit Menggunakan Darah Vena dan Darah Kapiler
Background: Platelets play a role in hemostasis which is the body's mechanisms to prevent and stop the bleeding. Platelets participate in the effort to close the wound, so that the body does not experience a loss of blood and protected from foreign cells.
Hieronymus Rayi Prasetya+2 more
doaj +1 more source
Assessment of neonatal, cord, and adult platelet granule trafficking and secretion
Despite the transient hyporeactivity of neonatal platelets, full-term neonates do not display a bleeding tendency, suggesting potential compensatory mechanisms which allow for balanced and efficient neonatal hemostasis.
Anh T. P. Ngo+12 more
doaj +1 more source
A comparison of haematopoietic stem cells from umbilical cord blood and peripheral blood for platelet production in a microfluidic device [PDF]
Background and objectives: Several sources of haematopoietic stem cells have been used for static culture of megakaryocytes to produce platelets in vitro.
Baruch, Dominique+5 more
core +1 more source
Platelet-mediated metabolism of the common dietary flavonoid, quercetin. [PDF]
BACKGROUND: Flavonoid metabolites remain in blood for periods of time potentially long enough to allow interactions with cellular components of this tissue.
Bernice Wright+5 more
core +7 more sources